SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oxn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWI_A_CAMA418_0
(CYTOCHROME P450-CAM)
3oxn PUTATIVE
TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY

(Vibrio
parahaemolyticus)
4 / 8 TYR A 291
THR A 123
VAL A 224
VAL A 190
None
0.94A 1iwiA-3oxnA:
undetectable
1iwiA-3oxnA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_G_SAMG199_0
(METHIONINE REPRESSOR)
3oxn PUTATIVE
TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY

(Vibrio
parahaemolyticus)
5 / 10 ARG A 156
GLU A 164
ALA A 166
LEU A 150
ALA A 121
None
1.16A 1mjqG-3oxnA:
undetectable
1mjqH-3oxnA:
undetectable
1mjqG-3oxnA:
18.93
1mjqH-3oxnA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)
3oxn PUTATIVE
TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY

(Vibrio
parahaemolyticus)
5 / 12 ILE A 170
THR A 123
ALA A 219
LEU A 319
TYR A 291
None
1.00A 1rjdA-3oxnA:
undetectable
1rjdA-3oxnA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)
3oxn PUTATIVE
TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY

(Vibrio
parahaemolyticus)
5 / 12 ILE A 170
THR A 123
ALA A 219
LEU A 319
TYR A 291
None
0.99A 1rjdB-3oxnA:
undetectable
1rjdB-3oxnA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)
3oxn PUTATIVE
TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY

(Vibrio
parahaemolyticus)
5 / 12 ILE A 170
THR A 123
ALA A 219
LEU A 319
TYR A 291
None
1.01A 1rjdC-3oxnA:
undetectable
1rjdC-3oxnA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z97_A_CAMA422_0
(CYTOCHROME P450-CAM)
3oxn PUTATIVE
TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY

(Vibrio
parahaemolyticus)
4 / 6 TYR A 291
THR A 123
VAL A 224
VAL A 190
None
0.83A 2z97A-3oxnA:
undetectable
2z97A-3oxnA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DAT_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)
3oxn PUTATIVE
TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY

(Vibrio
parahaemolyticus)
5 / 12 ALA A 126
LEU A 152
GLN A 153
ILE A 294
LEU A 161
None
1.17A 3datA-3oxnA:
undetectable
3datA-3oxnA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)
3oxn PUTATIVE
TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY

(Vibrio
parahaemolyticus)
4 / 7 VAL A 190
LEU A 282
TYR A 210
LEU A 194
None
1.01A 3qeoB-3oxnA:
undetectable
3qeoB-3oxnA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
3oxn PUTATIVE
TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY

(Vibrio
parahaemolyticus)
4 / 8 TYR A 291
THR A 123
VAL A 224
VAL A 190
None
0.88A 4l4bA-3oxnA:
undetectable
4l4bA-3oxnA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_A_BRLA501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3oxn PUTATIVE
TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY

(Vibrio
parahaemolyticus)
4 / 5 GLY A 165
LEU A 152
LEU A 180
LEU A 308
None
0.85A 4o8fA-3oxnA:
undetectable
4o8fA-3oxnA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_A_IPHA101_0
(INSULIN)
3oxn PUTATIVE
TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY

(Vibrio
parahaemolyticus)
5 / 10 LEU A 232
CYH A 192
LEU A 282
HIS A 215
LEU A 211
None
1.19A 4p65A-3oxnA:
undetectable
4p65B-3oxnA:
undetectable
4p65F-3oxnA:
undetectable
4p65H-3oxnA:
undetectable
4p65A-3oxnA:
6.87
4p65B-3oxnA:
11.52
4p65F-3oxnA:
11.52
4p65H-3oxnA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_A_D16A401_1
(ORF70)
3oxn PUTATIVE
TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY

(Vibrio
parahaemolyticus)
4 / 7 PHE A 286
ILE A 228
ASP A 234
PHE A 284
None
0.81A 5h3aA-3oxnA:
undetectable
5h3aA-3oxnA:
22.64