SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oy2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KVL_A_CLSA371_1
(BETA-LACTAMASE)		 3oy2 GLYCOSYLTRANSFERASE
B736L
(Paramecium
bursaria
Chlorella
virus
NY2A) 		5 / 10 GLY A   7
TYR A  97
ASN A  89
TYR A  16
GLY A  37
 None
 1.17A 1kvlA-3oy2A:
undetectable		 1kvlA-3oy2A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 3oy2 GLYCOSYLTRANSFERASE
B736L
(Paramecium
bursaria
Chlorella
virus
NY2A) 		5 / 10 ASP A 147
ILE A 334
GLY A 335
GLY A 336
ILE A 337
 None
 0.69A 1sdtA-3oy2A:
undetectable		 1sdtA-3oy2A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 3oy2 GLYCOSYLTRANSFERASE
B736L
(Paramecium
bursaria
Chlorella
virus
NY2A) 		5 / 11 ASP A 147
ILE A 334
GLY A 335
GLY A 336
ILE A 337
 None
 0.70A 1sduA-3oy2A:
undetectable		 1sduA-3oy2A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 3oy2 GLYCOSYLTRANSFERASE
B736L
(Paramecium
bursaria
Chlorella
virus
NY2A) 		5 / 10 ASP A 147
ILE A 334
GLY A 335
GLY A 336
ILE A 337
 None
 0.68A 1sdvA-3oy2A:
undetectable		 1sdvA-3oy2A:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_1
(POL POLYPROTEIN)		 3oy2 GLYCOSYLTRANSFERASE
B736L
(Paramecium
bursaria
Chlorella
virus
NY2A) 		5 / 12 ASP A 147
ILE A 334
GLY A 335
GLY A 336
ILE A 337
 None
 0.71A 2avvA-3oy2A:
undetectable		 2avvA-3oy2A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3oy2 GLYCOSYLTRANSFERASE
B736L
(Paramecium
bursaria
Chlorella
virus
NY2A) 		3 / 3 SER A 290
ASP A 309
CYH A 143
 None
 1.13A 2br4E-3oy2A:
undetectable		 2br4E-3oy2A:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_1
(PROTEASE)		 3oy2 GLYCOSYLTRANSFERASE
B736L
(Paramecium
bursaria
Chlorella
virus
NY2A) 		5 / 12 ASP A 147
ILE A 334
GLY A 335
GLY A 336
ILE A 337
 None
 0.73A 2r5pA-3oy2A:
undetectable		 2r5pA-3oy2A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_1
(PROTEASE)		 3oy2 GLYCOSYLTRANSFERASE
B736L
(Paramecium
bursaria
Chlorella
virus
NY2A) 		5 / 12 ASP A 147
ILE A 334
GLY A 335
GLY A 336
ILE A 337
 None
 0.73A 2r5pC-3oy2A:
undetectable		 2r5pC-3oy2A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3oy2 GLYCOSYLTRANSFERASE
B736L
(Paramecium
bursaria
Chlorella
virus
NY2A) 		5 / 12 SER A 282
PHE A 312
ILE A 302
ASN A 279
SER A 290
 None
 1.14A 2vdyB-3oy2A:
undetectable		 2vdyB-3oy2A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_B_SAMB501_0
(SPERMIDINE SYNTHASE)		 3oy2 GLYCOSYLTRANSFERASE
B736L
(Paramecium
bursaria
Chlorella
virus
NY2A) 		5 / 12 LEU A   3
HIS A  46
ILE A  38
GLY A   7
ILE A  87
 None
 1.03A 3bwcB-3oy2A:
2.8		 3bwcB-3oy2A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EQM_A_ASDA601_1
(CYTOCHROME P450 19A1)		 3oy2 GLYCOSYLTRANSFERASE
B736L
(Paramecium
bursaria
Chlorella
virus
NY2A) 		5 / 10 ILE A 128
PHE A 129
ILE A  92
ASP A  90
LEU A 116
 None
 1.17A 3eqmA-3oy2A:
undetectable		 3eqmA-3oy2A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_1
(GAG-POL POLYPROTEIN)		 3oy2 GLYCOSYLTRANSFERASE
B736L
(Paramecium
bursaria
Chlorella
virus
NY2A) 		6 / 12 ASP A 115
ASP A  90
VAL A  93
GLY A   7
ILE A   5
ILE A  94
 None
 1.38A 3jw2A-3oy2A:
undetectable		 3jw2A-3oy2A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_B_CGEB501_1
(CYTOCHROME P450 2B4)		 3oy2 GLYCOSYLTRANSFERASE
B736L
(Paramecium
bursaria
Chlorella
virus
NY2A) 		4 / 8 PHE A 209
ALA A 206
VAL A 278
VAL A 276
 None
 0.79A 3me6B-3oy2A:
undetectable		 3me6B-3oy2A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_B_DXCB92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3oy2 GLYCOSYLTRANSFERASE
B736L
(Paramecium
bursaria
Chlorella
virus
NY2A) 		4 / 5 VAL A 343
VAL A 347
ARG A 208
LYS A 254
 None
 1.45A 3rv5A-3oy2A:
0.0
3rv5B-3oy2A:
undetectable		 3rv5A-3oy2A:
13.91
3rv5B-3oy2A:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S79_A_ASDA601_1
(CYTOCHROME P450 19A1)		 3oy2 GLYCOSYLTRANSFERASE
B736L
(Paramecium
bursaria
Chlorella
virus
NY2A) 		5 / 12 ILE A 128
PHE A 129
ILE A  92
ASP A  90
LEU A 116
 None
 1.17A 3s79A-3oy2A:
undetectable		 3s79A-3oy2A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3oy2 GLYCOSYLTRANSFERASE
B736L
(Paramecium
bursaria
Chlorella
virus
NY2A) 		3 / 3 TYR A 362
LEU A 221
ARG A 359
 None
 0.56A 3sufB-3oy2A:
undetectable		 3sufB-3oy2A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3oy2 GLYCOSYLTRANSFERASE
B736L
(Paramecium
bursaria
Chlorella
virus
NY2A) 		4 / 4 ASN A  96
GLY A  95
ASP A 330
ASP A  90
 None
 1.22A 4n49A-3oy2A:
2.5		 4n49A-3oy2A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB203_1
(CALMODULIN)		 3oy2 GLYCOSYLTRANSFERASE
B736L
(Paramecium
bursaria
Chlorella
virus
NY2A) 		4 / 7 PHE A 387
LEU A   3
MET A  86
ALA A  30
 None
 1.01A 4rjdB-3oy2A:
undetectable		 4rjdB-3oy2A:
12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1728_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 3oy2 GLYCOSYLTRANSFERASE
B736L
(Paramecium
bursaria
Chlorella
virus
NY2A) 		3 / 3 ASN A 279
SER A 281
ARG A 196
 None
 0.82A 5b2qA-3oy2A:
undetectable		 5b2qA-3oy2A:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWK_D_EVPD102_1
(DNA TOPOISOMERASE
2-ALPHA)		 3oy2 GLYCOSYLTRANSFERASE
B736L
(Paramecium
bursaria
Chlorella
virus
NY2A) 		4 / 4 GLY A 335
ASP A 332
ARG A 196
MET A 138
 None
 1.48A 5gwkB-3oy2A:
3.1		 5gwkB-3oy2A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKV_A_ASDA602_1
(AROMATASE)		 3oy2 GLYCOSYLTRANSFERASE
B736L
(Paramecium
bursaria
Chlorella
virus
NY2A) 		5 / 12 ILE A 128
PHE A 129
ILE A  92
ASP A  90
LEU A 116
 None
 1.17A 5jkvA-3oy2A:
undetectable		 5jkvA-3oy2A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKW_A_TESA601_1
(AROMATASE)		 3oy2 GLYCOSYLTRANSFERASE
B736L
(Paramecium
bursaria
Chlorella
virus
NY2A) 		5 / 11 ILE A 128
PHE A 129
ILE A  92
ASP A  90
LEU A 116
 None
 1.18A 5jkwA-3oy2A:
undetectable		 5jkwA-3oy2A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JL7_A_ASDA601_1
(AROMATASE)		 3oy2 GLYCOSYLTRANSFERASE
B736L
(Paramecium
bursaria
Chlorella
virus
NY2A) 		5 / 10 ILE A 128
PHE A 129
ILE A  92
ASP A  90
LEU A 116
 None
 1.21A 5jl7A-3oy2A:
undetectable		 5jl7A-3oy2A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIG_A_EDTA501_0
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 3oy2 GLYCOSYLTRANSFERASE
B736L
(Paramecium
bursaria
Chlorella
virus
NY2A) 		4 / 6 ASN A 191
ASN A 279
ARG A 196
GLU A 292
 None
 1.31A 5uigA-3oy2A:
undetectable		 5uigA-3oy2A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 3oy2 GLYCOSYLTRANSFERASE
B736L
(Paramecium
bursaria
Chlorella
virus
NY2A) 		4 / 8 LEU A 300
VAL A 317
VAL A 366
PHE A 369
 None
 0.77A 5y9mA-3oy2A:
undetectable		 5y9mA-3oy2A:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWV_A_BEZA202_0
(ARA H 8 ALLERGEN)		 3oy2 GLYCOSYLTRANSFERASE
B736L
(Paramecium
bursaria
Chlorella
virus
NY2A) 		4 / 4 PHE A 312
ASP A 309
LEU A 300
LYS A 319
 None
 1.38A 6awvA-3oy2A:
undetectable		 6awvA-3oy2A:
17.20