SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oyo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3oyo HEMOPEXIN FOLD
PROTEIN CP4
(Vigna
unguiculata) 		4 / 8 ALA A 185
ASP A 121
ILE A 173
ILE A 157
 None
 0.88A 1p7lD-3oyoA:
undetectable		 1p7lD-3oyoA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3oyo HEMOPEXIN FOLD
PROTEIN CP4
(Vigna
unguiculata) 		4 / 8 ALA A 185
ASP A 121
ILE A 173
ILE A 157
 None
 0.90A 1p7lC-3oyoA:
undetectable		 1p7lC-3oyoA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3oyo HEMOPEXIN FOLD
PROTEIN CP4
(Vigna
unguiculata) 		4 / 8 ALA A 185
ASP A 121
ILE A 173
ILE A 157
 None
 0.85A 1rg9B-3oyoA:
undetectable		 1rg9B-3oyoA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3oyo HEMOPEXIN FOLD
PROTEIN CP4
(Vigna
unguiculata) 		4 / 8 ALA A 185
ASP A 121
ILE A 173
ILE A 157
 None
 0.86A 1rg9A-3oyoA:
undetectable		 1rg9A-3oyoA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3oyo HEMOPEXIN FOLD
PROTEIN CP4
(Vigna
unguiculata) 		4 / 8 ALA A 185
ASP A 121
ILE A 173
ILE A 157
 None
 0.86A 1rg9D-3oyoA:
undetectable		 1rg9D-3oyoA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3oyo HEMOPEXIN FOLD
PROTEIN CP4
(Vigna
unguiculata) 		4 / 8 ALA A 185
ASP A 121
ILE A 173
ILE A 157
 None
 0.88A 1rg9C-3oyoA:
undetectable		 1rg9C-3oyoA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_B_CHDB701_0
(FERROCHELATASE)		 3oyo HEMOPEXIN FOLD
PROTEIN CP4
(Vigna
unguiculata) 		3 / 3 LYS A 148
GLY A 100
PRO A 101
 None
 1.02A 2hreB-3oyoA:
undetectable		 2hreB-3oyoA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_2
(PROTEASE)		 3oyo HEMOPEXIN FOLD
PROTEIN CP4
(Vigna
unguiculata) 		5 / 9 LEU A 150
VAL A 132
ILE A 104
VAL A 141
ILE A 143
 None
 0.88A 2o4pB-3oyoA:
undetectable		 2o4pB-3oyoA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_1
(PROTEASE)		 3oyo HEMOPEXIN FOLD
PROTEIN CP4
(Vigna
unguiculata) 		5 / 12 LEU A 150
VAL A 132
ILE A 104
VAL A 141
ILE A 143
 None
 1.02A 2r5pA-3oyoA:
undetectable		 2r5pA-3oyoA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_1
(PROTEASE)		 3oyo HEMOPEXIN FOLD
PROTEIN CP4
(Vigna
unguiculata) 		5 / 12 LEU A 150
VAL A 132
ILE A 104
VAL A 141
ILE A 143
 None
 1.02A 2r5pC-3oyoA:
undetectable		 2r5pC-3oyoA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B2R_A_VDNA1_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3oyo HEMOPEXIN FOLD
PROTEIN CP4
(Vigna
unguiculata) 		5 / 12 LEU A  98
ILE A  97
VAL A  77
PHE A  10
ILE A  47
 None
 1.11A 3b2rA-3oyoA:
undetectable		 3b2rA-3oyoA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_B_PZIB802_0
(GLUTAMATE RECEPTOR 2)		 3oyo HEMOPEXIN FOLD
PROTEIN CP4
(Vigna
unguiculata) 		3 / 3 SER A 119
ASP A  65
ASN A   7
 None
None
CA  A 228 (-3.5A)
 0.99A 3lsfB-3oyoA:
undetectable
3lsfE-3oyoA:
undetectable		 3lsfB-3oyoA:
23.96
3lsfE-3oyoA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_E_PZIE802_0
(GLUTAMATE RECEPTOR 2)		 3oyo HEMOPEXIN FOLD
PROTEIN CP4
(Vigna
unguiculata) 		3 / 3 ASP A  65
ASN A   7
SER A 119
 None
CA  A 228 (-3.5A)
None
 1.01A 3lsfB-3oyoA:
undetectable
3lsfE-3oyoA:
undetectable		 3lsfB-3oyoA:
23.96
3lsfE-3oyoA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OCT_A_1N1A663_2
(TYROSINE-PROTEIN
KINASE BTK)		 3oyo HEMOPEXIN FOLD
PROTEIN CP4
(Vigna
unguiculata) 		4 / 5 PHE A  20
ILE A  64
ASN A 192
PHE A  10
 None
 1.15A 3octA-3oyoA:
undetectable		 3octA-3oyoA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_2
(PROTEASE)		 3oyo HEMOPEXIN FOLD
PROTEIN CP4
(Vigna
unguiculata) 		5 / 12 LEU A 150
VAL A 132
ILE A 104
VAL A 141
ILE A 143
 None
 0.94A 3pwmB-3oyoA:
undetectable		 3pwmB-3oyoA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1003_1
(HEMOLYTIC LECTIN
CEL-III)		 3oyo HEMOPEXIN FOLD
PROTEIN CP4
(Vigna
unguiculata) 		4 / 4 ASP A 146
GLU A 131
GLY A 129
TYR A 145
 None
 1.14A 3w9tA-3oyoA:
0.0		 3w9tA-3oyoA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		 3oyo HEMOPEXIN FOLD
PROTEIN CP4
(Vigna
unguiculata) 		4 / 5 ASP A 146
GLU A 131
GLY A 129
TYR A 145
 None
 1.27A 3w9tA-3oyoA:
undetectable		 3w9tA-3oyoA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB507_1
(HEMOLYTIC LECTIN
CEL-III)		 3oyo HEMOPEXIN FOLD
PROTEIN CP4
(Vigna
unguiculata) 		4 / 4 ASP A 146
GLU A 131
GLY A 129
TYR A 145
 None
 1.13A 3w9tB-3oyoA:
0.0		 3w9tB-3oyoA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		 3oyo HEMOPEXIN FOLD
PROTEIN CP4
(Vigna
unguiculata) 		4 / 5 ASP A 146
GLU A 131
GLY A 129
TYR A 145
 None
 1.27A 3w9tC-3oyoA:
undetectable		 3w9tC-3oyoA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		 3oyo HEMOPEXIN FOLD
PROTEIN CP4
(Vigna
unguiculata) 		4 / 5 ASP A 146
GLU A 131
GLY A 129
TYR A 145
 None
 1.13A 3w9tD-3oyoA:
undetectable		 3w9tD-3oyoA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		 3oyo HEMOPEXIN FOLD
PROTEIN CP4
(Vigna
unguiculata) 		4 / 5 ASP A 146
GLU A 131
GLY A 129
TYR A 145
 None
 1.26A 3w9tD-3oyoA:
undetectable		 3w9tD-3oyoA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE503_1
(HEMOLYTIC LECTIN
CEL-III)		 3oyo HEMOPEXIN FOLD
PROTEIN CP4
(Vigna
unguiculata) 		4 / 4 ASP A 146
GLU A 131
GLY A 129
TYR A 145
 None
 1.13A 3w9tE-3oyoA:
0.0		 3w9tE-3oyoA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF502_1
(HEMOLYTIC LECTIN
CEL-III)		 3oyo HEMOPEXIN FOLD
PROTEIN CP4
(Vigna
unguiculata) 		4 / 4 ASP A 146
GLU A 131
GLY A 129
TYR A 145
 None
 1.13A 3w9tF-3oyoA:
0.0		 3w9tF-3oyoA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		 3oyo HEMOPEXIN FOLD
PROTEIN CP4
(Vigna
unguiculata) 		4 / 5 ASP A 146
GLU A 131
GLY A 129
TYR A 145
 None
 1.27A 3w9tG-3oyoA:
undetectable		 3w9tG-3oyoA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGJ_A_1PQA304_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3oyo HEMOPEXIN FOLD
PROTEIN CP4
(Vigna
unguiculata) 		4 / 8 PHE A  10
ILE A  86
PHE A  21
GLY A  50
 None
 1.00A 4fgjA-3oyoA:
undetectable
4fgjB-3oyoA:
undetectable		 4fgjA-3oyoA:
22.05
4fgjB-3oyoA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3oyo HEMOPEXIN FOLD
PROTEIN CP4
(Vigna
unguiculata) 		4 / 8 ALA A 185
ASP A 121
ILE A 173
ILE A 157
 None
 0.89A 4kttB-3oyoA:
undetectable		 4kttB-3oyoA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3oyo HEMOPEXIN FOLD
PROTEIN CP4
(Vigna
unguiculata) 		4 / 8 ALA A 185
ASP A 121
ILE A 173
ILE A 157
 None
 0.86A 4kttD-3oyoA:
undetectable		 4kttD-3oyoA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3oyo HEMOPEXIN FOLD
PROTEIN CP4
(Vigna
unguiculata) 		6 / 12 ALA A 175
PRO A   4
GLY A 190
PHE A 188
ILE A 224
LEU A  44
 CL  A 229 ( 4.1A)
None
None
None
None
None
 1.37A 4n49A-3oyoA:
undetectable		 4n49A-3oyoA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3oyo HEMOPEXIN FOLD
PROTEIN CP4
(Vigna
unguiculata) 		4 / 8 ALA A 185
ASP A 121
ILE A 173
ILE A 157
 None
 0.85A 4ndnD-3oyoA:
undetectable		 4ndnD-3oyoA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3oyo HEMOPEXIN FOLD
PROTEIN CP4
(Vigna
unguiculata) 		4 / 8 ALA A 185
ASP A 121
ILE A 173
ILE A 157
 None
 0.89A 5t8sA-3oyoA:
undetectable		 5t8sA-3oyoA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_1
(HIV-1 PROTEASE)		 3oyo HEMOPEXIN FOLD
PROTEIN CP4
(Vigna
unguiculata) 		5 / 12 LEU A 150
VAL A 132
ILE A 104
VAL A 141
ILE A 143
 None
 0.94A 6difB-3oyoA:
undetectable		 6difB-3oyoA:
17.86