SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3oz7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4001_1
(SERUM ALBUMIN)		 3oz7 PHOSPHOGLYCERATE
KINASE
(Plasmodium
falciparum) 		5 / 9 ILE A 369
PHE A 165
LEU A 407
GLY A 394
LEU A 402
 None
 1.24A 1e7aB-3oz7A:
undetectable		 1e7aB-3oz7A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3oz7 PHOSPHOGLYCERATE
KINASE
(Plasmodium
falciparum) 		5 / 12 ILE A 367
ALA A 199
LEU A 200
LEU A 226
LEU A 208
 None
 1.19A 1g5yB-3oz7A:
undetectable		 1g5yB-3oz7A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEI_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 3oz7 PHOSPHOGLYCERATE
KINASE
(Plasmodium
falciparum) 		4 / 8 SER A 185
ASN A 162
ILE A 161
GLU A 192
 None
 1.00A 1meiA-3oz7A:
undetectable		 1meiA-3oz7A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3oz7 PHOSPHOGLYCERATE
KINASE
(Plasmodium
falciparum) 		3 / 3 ASN A 386
ASN A 383
GLU A 380
 None
 0.86A 3kpdB-3oz7A:
undetectable		 3kpdB-3oz7A:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_A_ADNA300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 3oz7 PHOSPHOGLYCERATE
KINASE
(Plasmodium
falciparum) 		5 / 11 ALA A 184
ILE A 161
GLY A 186
LEU A  11
THR A  46
 None
 1.10A 3kw2A-3oz7A:
2.4		 3kw2A-3oz7A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_B_ADNB300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 3oz7 PHOSPHOGLYCERATE
KINASE
(Plasmodium
falciparum) 		5 / 11 ALA A 184
ILE A 161
GLY A 186
LEU A  11
THR A  46
 None
 1.13A 3kw2B-3oz7A:
3.0		 3kw2B-3oz7A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_A_FLPA701_1
(CYCLOOXYGENASE-2)		 3oz7 PHOSPHOGLYCERATE
KINASE
(Plasmodium
falciparum) 		5 / 12 VAL A  21
LEU A  50
VAL A 182
ALA A 184
SER A   7
 None
 1.22A 3pghA-3oz7A:
undetectable		 3pghA-3oz7A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QJ7_A_SPMA264_1
(THYMIDYLATE SYNTHASE)		 3oz7 PHOSPHOGLYCERATE
KINASE
(Plasmodium
falciparum) 		4 / 8 ALA A 214
LEU A 256
ASP A 258
SER A 217
 SO4  A 501 (-3.6A)
None
None
None
 0.82A 3qj7A-3oz7A:
undetectable
3qj7D-3oz7A:
undetectable		 3qj7A-3oz7A:
20.44
3qj7D-3oz7A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_C_FLRC700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3oz7 PHOSPHOGLYCERATE
KINASE
(Plasmodium
falciparum) 		5 / 12 VAL A 410
LEU A 402
LEU A   2
GLY A 396
ALA A 397
 None
 1.00A 3rr3C-3oz7A:
undetectable		 3rr3C-3oz7A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_D_FLRD700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3oz7 PHOSPHOGLYCERATE
KINASE
(Plasmodium
falciparum) 		5 / 12 VAL A 410
LEU A 402
LEU A   2
GLY A 396
ALA A 397
 None
 1.00A 3rr3D-3oz7A:
undetectable		 3rr3D-3oz7A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CCQ_A_ACTA1317_0
(THIOREDOXIN
REDUCTASE)		 3oz7 PHOSPHOGLYCERATE
KINASE
(Plasmodium
falciparum) 		3 / 3 LEU A 355
GLU A 353
SER A 351
 None
 0.56A 4ccqA-3oz7A:
3.3		 4ccqA-3oz7A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_A_ADNA401_1
(APH(2'')-ID)		 3oz7 PHOSPHOGLYCERATE
KINASE
(Plasmodium
falciparum) 		5 / 11 GLY A 261
ILE A 268
ILE A 279
LEU A 281
ILE A 235
 None
 1.04A 4dt8A-3oz7A:
undetectable		 4dt8A-3oz7A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3oz7 PHOSPHOGLYCERATE
KINASE
(Plasmodium
falciparum) 		4 / 6 ASN A 356
GLU A 360
TYR A 323
GLU A 353
 None
 1.13A 4mi4A-3oz7A:
undetectable		 4mi4A-3oz7A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3oz7 PHOSPHOGLYCERATE
KINASE
(Plasmodium
falciparum) 		4 / 8 ASN A 356
GLU A 360
TYR A 323
GLU A 353
 None
 1.14A 4mj8A-3oz7A:
undetectable
4mj8C-3oz7A:
undetectable		 4mj8A-3oz7A:
17.75
4mj8C-3oz7A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3oz7 PHOSPHOGLYCERATE
KINASE
(Plasmodium
falciparum) 		4 / 7 ASN A 356
GLU A 360
TYR A 323
GLU A 353
 None
 1.01A 4mj8C-3oz7A:
undetectable		 4mj8C-3oz7A:
17.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 3oz7 PHOSPHOGLYCERATE
KINASE
(Plasmodium
falciparum) 		9 / 12 GLY A 213
ALA A 214
GLY A 237
GLY A 238
THR A 254
LEU A 256
MET A 311
LEU A 313
GLY A 340
 SO4  A 501 (-3.2A)
SO4  A 501 (-3.6A)
None
None
None
None
None
None
None
 0.64A 4o33A-3oz7A:
53.7		 4o33A-3oz7A:
60.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 3oz7 PHOSPHOGLYCERATE
KINASE
(Plasmodium
falciparum) 		9 / 12 GLY A 213
ALA A 214
GLY A 237
GLY A 238
THR A 254
MET A 311
LEU A 313
GLY A 340
VAL A 341
 SO4  A 501 (-3.2A)
SO4  A 501 (-3.6A)
None
None
None
None
None
None
None
 0.52A 4o33A-3oz7A:
53.7		 4o33A-3oz7A:
60.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 3oz7 PHOSPHOGLYCERATE
KINASE
(Plasmodium
falciparum) 		9 / 12 GLY A 213
ALA A 214
GLY A 238
THR A 254
PHE A 291
MET A 311
LEU A 313
GLY A 340
VAL A 341
 SO4  A 501 (-3.2A)
SO4  A 501 (-3.6A)
None
None
None
None
None
None
None
 0.60A 4o33A-3oz7A:
53.7		 4o33A-3oz7A:
60.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 3oz7 PHOSPHOGLYCERATE
KINASE
(Plasmodium
falciparum) 		7 / 12 GLY A 213
ALA A 214
GLY A 237
GLY A 238
THR A 254
LEU A 256
GLY A 340
 SO4  A 501 (-3.2A)
SO4  A 501 (-3.6A)
None
None
None
None
None
 0.76A 4o3fA-3oz7A:
52.1		 4o3fA-3oz7A:
59.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 3oz7 PHOSPHOGLYCERATE
KINASE
(Plasmodium
falciparum) 		9 / 12 GLY A 213
ALA A 214
GLY A 237
GLY A 238
THR A 254
MET A 311
LEU A 313
GLY A 340
VAL A 341
 SO4  A 501 (-3.2A)
SO4  A 501 (-3.6A)
None
None
None
None
None
None
None
 0.52A 4o3fA-3oz7A:
52.1		 4o3fA-3oz7A:
59.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 3oz7 PHOSPHOGLYCERATE
KINASE
(Plasmodium
falciparum) 		9 / 12 GLY A 213
ALA A 214
GLY A 238
THR A 254
PHE A 291
MET A 311
LEU A 313
GLY A 340
VAL A 341
 SO4  A 501 (-3.2A)
SO4  A 501 (-3.6A)
None
None
None
None
None
None
None
 0.57A 4o3fA-3oz7A:
52.1		 4o3fA-3oz7A:
59.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_H_SPMH202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3oz7 PHOSPHOGLYCERATE
KINASE
(Plasmodium
falciparum) 		4 / 6 ASN A 356
GLU A 360
TYR A 323
GLU A 353
 None
 1.22A 4r87H-3oz7A:
undetectable		 4r87H-3oz7A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3oz7 PHOSPHOGLYCERATE
KINASE
(Plasmodium
falciparum) 		5 / 12 GLY A 166
LEU A 402
ILE A 223
GLY A 212
THR A 393
 None
 1.14A 4ze2A-3oz7A:
undetectable		 4ze2A-3oz7A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E72_A_SAMA400_1
(N2,
N2-DIMETHYLGUANOSINE
TRNA
METHYLTRANSFERASE)		 3oz7 PHOSPHOGLYCERATE
KINASE
(Plasmodium
falciparum) 		4 / 4 ASP A  97
GLY A 100
ASP A 152
ASP A 145
 None
 1.09A 5e72A-3oz7A:
3.7		 5e72A-3oz7A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 3oz7 PHOSPHOGLYCERATE
KINASE
(Plasmodium
falciparum) 		3 / 3 LYS A  15
ASP A  13
ILE A  58
 None
 0.88A 5kc4E-3oz7A:
undetectable		 5kc4E-3oz7A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_A_SAMA401_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3oz7 PHOSPHOGLYCERATE
KINASE
(Plasmodium
falciparum) 		5 / 12 LEU A 211
GLY A 337
ILE A 223
GLY A 213
GLY A 212
 None
None
None
SO4  A 501 (-3.2A)
None
 1.11A 5wyqA-3oz7A:
undetectable		 5wyqA-3oz7A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1431_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3oz7 PHOSPHOGLYCERATE
KINASE
(Plasmodium
falciparum) 		4 / 7 ASN A  26
HIS A  63
GLY A  69
ASN A 120
 SO4  A 601 ( 4.5A)
SO4  A 601 (-4.4A)
None
None
 1.13A 5x7pA-3oz7A:
undetectable		 5x7pA-3oz7A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_A_SAMA601_0
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 3oz7 PHOSPHOGLYCERATE
KINASE
(Plasmodium
falciparum) 		5 / 12 GLY A  69
GLY A 131
PRO A  67
LEU A 153
PHE A 149
 None
 1.16A 5ybbA-3oz7A:
undetectable		 5ybbA-3oz7A:
21.66