SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ozb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_2
(ESTROGEN RECEPTOR)		 3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE
(Pseudomonas
aeruginosa) 		4 / 6 LEU A  62
LEU A  32
LEU A 213
LEU A 211
 None
 0.88A 1errA-3ozbA:
undetectable		 1errA-3ozbA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_1_T441128_1
(TRANSTHYRETIN)		 3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE
(Pseudomonas
aeruginosa) 		4 / 6 LEU A  51
GLU A  60
ALA A  19
LEU A  64
 None
SO4  A 262 (-3.1A)
None
None
 1.14A 1etb1-3ozbA:
undetectable		 1etb1-3ozbA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_A_T44A128_1
(TRANSTHYRETIN)		 3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE
(Pseudomonas
aeruginosa) 		5 / 10 ALA A  86
LEU A  84
GLU A  60
ALA A  19
LEU A  64
 None
None
SO4  A 262 (-3.1A)
None
None
 0.94A 1ie4A-3ozbA:
undetectable
1ie4C-3ozbA:
undetectable		 1ie4A-3ozbA:
22.17
1ie4C-3ozbA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_A_T44A128_1
(TRANSTHYRETIN)		 3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE
(Pseudomonas
aeruginosa) 		5 / 10 LEU A  51
GLU A  60
ALA A  19
LEU A  64
LEU A  84
 None
SO4  A 262 (-3.1A)
None
None
None
 1.11A 1ie4A-3ozbA:
undetectable
1ie4C-3ozbA:
undetectable		 1ie4A-3ozbA:
22.17
1ie4C-3ozbA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_A_T44A128_1
(TRANSTHYRETIN)		 3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE
(Pseudomonas
aeruginosa) 		5 / 10 LEU A 213
LEU A  84
GLU A  60
ALA A  19
LEU A  64
 None
None
SO4  A 262 (-3.1A)
None
None
 1.04A 1ie4A-3ozbA:
undetectable
1ie4C-3ozbA:
undetectable		 1ie4A-3ozbA:
22.17
1ie4C-3ozbA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_B_T44B328_1
(TRANSTHYRETIN)		 3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE
(Pseudomonas
aeruginosa) 		4 / 8 ALA A  86
LEU A  84
GLU A  60
ALA A  19
 None
None
SO4  A 262 (-3.1A)
None
 0.93A 1ie4B-3ozbA:
undetectable
1ie4D-3ozbA:
undetectable		 1ie4B-3ozbA:
22.17
1ie4D-3ozbA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PWY_E_AC2E290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE
(Pseudomonas
aeruginosa) 		6 / 10 GLY A 102
GLU A 181
VAL A 197
GLY A 198
MET A 199
ASN A 223
 HPA  A 260 (-3.7A)
HPA  A 260 (-2.9A)
HPA  A 260 (-4.3A)
HPA  A 260 (-3.3A)
HPA  A 260 (-4.3A)
HPA  A 260 (-3.0A)
 0.52A 1pwyE-3ozbA:
23.4		 1pwyE-3ozbA:
25.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN0_C_T44C601_1
(TRANSTHYRETIN)		 3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE
(Pseudomonas
aeruginosa) 		5 / 9 ALA A  86
LEU A  84
LEU A  51
GLU A  60
ALA A  19
 None
None
None
SO4  A 262 (-3.1A)
None
 1.24A 1sn0A-3ozbA:
undetectable
1sn0C-3ozbA:
undetectable		 1sn0A-3ozbA:
21.88
1sn0C-3ozbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_D_T3D602_1
(TRANSTHYRETIN)		 3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE
(Pseudomonas
aeruginosa) 		6 / 12 ALA A  86
LEU A  84
LEU A  51
GLU A  60
ALA A  19
LEU A  64
 None
None
None
SO4  A 262 (-3.1A)
None
None
 1.14A 1sn5B-3ozbA:
undetectable
1sn5D-3ozbA:
undetectable		 1sn5B-3ozbA:
21.88
1sn5D-3ozbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_D_T3D602_1
(TRANSTHYRETIN)		 3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE
(Pseudomonas
aeruginosa) 		5 / 12 GLU A  60
ALA A  19
LEU A  64
LEU A 213
LEU A  84
 SO4  A 262 (-3.1A)
None
None
None
None
 1.05A 1sn5B-3ozbA:
undetectable
1sn5D-3ozbA:
undetectable		 1sn5B-3ozbA:
21.88
1sn5D-3ozbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_D_T3D602_1
(TRANSTHYRETIN)		 3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE
(Pseudomonas
aeruginosa) 		6 / 12 LEU A  51
GLU A  60
ALA A  19
LEU A  64
ALA A  86
LEU A  84
 None
SO4  A 262 (-3.1A)
None
None
None
None
 1.14A 1sn5B-3ozbA:
undetectable
1sn5D-3ozbA:
undetectable		 1sn5B-3ozbA:
21.88
1sn5D-3ozbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_D_T3D602_1
(TRANSTHYRETIN)		 3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 213
LEU A  84
GLU A  60
ALA A  19
LEU A  64
 None
None
SO4  A 262 (-3.1A)
None
None
 1.03A 1sn5B-3ozbA:
undetectable
1sn5D-3ozbA:
undetectable		 1sn5B-3ozbA:
21.88
1sn5D-3ozbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V3Q_E_2DIE290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE
(Pseudomonas
aeruginosa) 		6 / 10 GLY A 102
GLU A 181
VAL A 197
GLY A 198
MET A 199
ASN A 223
 HPA  A 260 (-3.7A)
HPA  A 260 (-2.9A)
HPA  A 260 (-4.3A)
HPA  A 260 (-3.3A)
HPA  A 260 (-4.3A)
HPA  A 260 (-3.0A)
 0.32A 1v3qE-3ozbA:
24.2		 1v3qE-3ozbA:
25.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_A_SAMA301_0
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 201
ALA A  97
ILE A  21
GLU A 127
ALA A 206
 None
 1.44A 1vq1A-3ozbA:
undetectable		 1vq1A-3ozbA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2888_0
(AMINOMETHYLTRANSFERA
SE)		 3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE
(Pseudomonas
aeruginosa) 		5 / 10 LEU A  64
LEU A  87
ILE A  21
ILE A 141
LEU A 213
 None
 1.17A 1wopA-3ozbA:
undetectable		 1wopA-3ozbA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_A_RBFA300_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE
(Pseudomonas
aeruginosa) 		5 / 11 TYR A 172
GLY A 201
GLU A 204
ILE A  21
ALA A  97
 None
 1.33A 2a58A-3ozbA:
5.0
2a58E-3ozbA:
5.0		 2a58A-3ozbA:
22.43
2a58E-3ozbA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_D_RBFD303_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE
(Pseudomonas
aeruginosa) 		5 / 11 ILE A  21
ALA A  97
TYR A 172
GLY A 201
GLU A 204
 None
 1.33A 2a58C-3ozbA:
4.8
2a58D-3ozbA:
5.0		 2a58C-3ozbA:
22.43
2a58D-3ozbA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2001_1
(SERUM ALBUMIN)		 3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE
(Pseudomonas
aeruginosa) 		5 / 11 VAL A 197
GLY A 198
ALA A 173
LEU A 189
ARG A 188
 HPA  A 260 (-4.3A)
HPA  A 260 (-3.3A)
None
None
None
 1.19A 2bxgA-3ozbA:
undetectable		 2bxgA-3ozbA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_C_NCAC1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE
(Pseudomonas
aeruginosa) 		4 / 6 ARG A  59
SER A  16
ARG A 154
GLU A  93
 None
 1.43A 2c8aC-3ozbA:
undetectable		 2c8aC-3ozbA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_A_ACTA700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE
(Pseudomonas
aeruginosa) 		5 / 6 GLY A 102
GLU A 181
GLY A 198
MET A 199
ASN A 223
 HPA  A 260 (-3.7A)
HPA  A 260 (-2.9A)
HPA  A 260 (-3.3A)
HPA  A 260 (-4.3A)
HPA  A 260 (-3.0A)
 0.62A 3e9rA-3ozbA:
24.8		 3e9rA-3ozbA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_C_ACTC700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE
(Pseudomonas
aeruginosa) 		5 / 6 GLY A 102
GLU A 181
GLY A 198
MET A 199
ASN A 223
 HPA  A 260 (-3.7A)
HPA  A 260 (-2.9A)
HPA  A 260 (-3.3A)
HPA  A 260 (-4.3A)
HPA  A 260 (-3.0A)
 0.64A 3e9rC-3ozbA:
24.8		 3e9rC-3ozbA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_A_ADNA300_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE
(Pseudomonas
aeruginosa) 		6 / 12 ALA A 100
GLU A 181
GLY A 198
MET A 199
ASN A 223
VAL A 222
 HPA  A 260 (-4.6A)
HPA  A 260 (-2.9A)
HPA  A 260 (-3.3A)
HPA  A 260 (-4.3A)
HPA  A 260 (-3.0A)
None
 1.36A 3f8wA-3ozbA:
25.0		 3f8wA-3ozbA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_A_ADNA300_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE
(Pseudomonas
aeruginosa) 		7 / 12 ALA A 100
GLY A 102
GLU A 181
VAL A 197
GLY A 198
MET A 199
ASN A 223
 HPA  A 260 (-4.6A)
HPA  A 260 (-3.7A)
HPA  A 260 (-2.9A)
HPA  A 260 (-4.3A)
HPA  A 260 (-3.3A)
HPA  A 260 (-4.3A)
HPA  A 260 (-3.0A)
 0.44A 3f8wA-3ozbA:
25.0		 3f8wA-3ozbA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_B_ADNB301_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE
(Pseudomonas
aeruginosa) 		5 / 12 GLU A 181
GLY A 198
MET A 199
ASN A 223
VAL A 222
 HPA  A 260 (-2.9A)
HPA  A 260 (-3.3A)
HPA  A 260 (-4.3A)
HPA  A 260 (-3.0A)
None
 1.20A 3f8wB-3ozbA:
25.0		 3f8wB-3ozbA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_B_ADNB301_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE
(Pseudomonas
aeruginosa) 		6 / 12 GLY A 102
GLU A 181
VAL A 197
GLY A 198
MET A 199
ASN A 223
 HPA  A 260 (-3.7A)
HPA  A 260 (-2.9A)
HPA  A 260 (-4.3A)
HPA  A 260 (-3.3A)
HPA  A 260 (-4.3A)
HPA  A 260 (-3.0A)
 0.40A 3f8wB-3ozbA:
25.0		 3f8wB-3ozbA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_C_ADNC302_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE
(Pseudomonas
aeruginosa) 		6 / 12 ALA A 100
GLU A 181
GLY A 198
MET A 199
ASN A 223
VAL A 222
 HPA  A 260 (-4.6A)
HPA  A 260 (-2.9A)
HPA  A 260 (-3.3A)
HPA  A 260 (-4.3A)
HPA  A 260 (-3.0A)
None
 1.37A 3f8wC-3ozbA:
25.1		 3f8wC-3ozbA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_C_ADNC302_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE
(Pseudomonas
aeruginosa) 		7 / 12 ALA A 100
GLY A 102
GLU A 181
VAL A 197
GLY A 198
MET A 199
ASN A 223
 HPA  A 260 (-4.6A)
HPA  A 260 (-3.7A)
HPA  A 260 (-2.9A)
HPA  A 260 (-4.3A)
HPA  A 260 (-3.3A)
HPA  A 260 (-4.3A)
HPA  A 260 (-3.0A)
 0.44A 3f8wC-3ozbA:
25.1		 3f8wC-3ozbA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_1
(FIV PROTEASE)		 3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE
(Pseudomonas
aeruginosa) 		5 / 10 LEU A 257
ILE A 246
VAL A 249
ILE A  21
LEU A 253
 None
 0.92A 3ogqA-3ozbA:
undetectable		 3ogqA-3ozbA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V20_A_ACTA1444_0
(CELLOBIOHYDROLASE)		 3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE
(Pseudomonas
aeruginosa) 		4 / 5 GLY A  23
THR A  24
HIS A  67
GLY A  68
 None
 1.08A 4v20A-3ozbA:
undetectable		 4v20A-3ozbA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_E_ACTE403_0
(PROTON-GATED ION
CHANNEL)		 3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE
(Pseudomonas
aeruginosa) 		3 / 3 ARG A  66
TYR A 215
GLU A 204
 None
 0.44A 4zzbE-3ozbA:
undetectable		 4zzbE-3ozbA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE
(Pseudomonas
aeruginosa) 		3 / 3 GLU A  41
TRP A  85
ASN A  79
 None
 1.03A 5dv4A-3ozbA:
undetectable		 5dv4A-3ozbA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_1
(PAVINE
N-METHYLTRANSFERASE)		 3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE
(Pseudomonas
aeruginosa) 		4 / 5 PHE A 143
SER A 144
ASN A 194
ASP A 195
 None
None
None
SO4  A 261 ( 4.5A)
 1.50A 5kpcA-3ozbA:
undetectable		 5kpcA-3ozbA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQ4_B_ADNB401_1
(THERMOSPERMINE
SYNTHASE ACAULIS
PROTEIN)		 3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 198
ILE A 196
VAL A 222
ALA A 173
PRO A 116
 HPA  A 260 (-3.3A)
None
None
None
None
 1.08A 6bq4B-3ozbA:
undetectable		 6bq4B-3ozbA:
16.81