SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ozq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1872_0
(FPRA)		 3ozq SERPIN48
(Tenebrio
molitor) 		4 / 5 SER A 335
ALA A 341
ASP A 333
GLU A 340
 None
 1.47A 1lqtA-3ozqA:
undetectable
1lqtB-3ozqA:
undetectable		 1lqtA-3ozqA:
22.27
1lqtB-3ozqA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1429_0
(FPRA)		 3ozq SERPIN48
(Tenebrio
molitor) 		4 / 5 SER A 335
ALA A 341
ASP A 333
GLU A 340
 None
 1.48A 1lquA-3ozqA:
undetectable
1lquB-3ozqA:
undetectable		 1lquA-3ozqA:
22.27
1lquB-3ozqA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_2
(DNA TOPOISOMERASE II)		 3ozq SERPIN48
(Tenebrio
molitor) 		4 / 7 HIS A 229
ASN A 271
TYR A 225
LEU A 234
 None
 1.07A 1qzrB-3ozqA:
undetectable		 1qzrB-3ozqA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3ozq SERPIN48
(Tenebrio
molitor) 		4 / 5 PHE A  24
LEU A  94
PHE A  79
SER A  63
 None
 1.30A 1wrkB-3ozqA:
undetectable		 1wrkB-3ozqA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_C_TFPC208_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3ozq SERPIN48
(Tenebrio
molitor) 		4 / 5 PHE A  24
LEU A  94
PHE A  79
SER A  63
 None
 1.23A 1wrlC-3ozqA:
undetectable		 1wrlC-3ozqA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_B_ADNB1302_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3ozq SERPIN48
(Tenebrio
molitor) 		4 / 6 GLU A 168
ALA A 145
PRO A 167
ALA A 146
 None
 1.17A 2zgwB-3ozqA:
undetectable		 2zgwB-3ozqA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_1
(CYTOCHROME P450 2R1)		 3ozq SERPIN48
(Tenebrio
molitor) 		5 / 12 VAL A  28
ALA A  27
ALA A  89
VAL A  35
THR A  32
 None
 1.01A 3czhA-3ozqA:
undetectable		 3czhA-3ozqA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3ozq SERPIN48
(Tenebrio
molitor) 		4 / 7 ILE A  73
GLY A  64
VAL A  90
LEU A 178
 None
 0.91A 3elzA-3ozqA:
0.9		 3elzA-3ozqA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_B_DXCB92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3ozq SERPIN48
(Tenebrio
molitor) 		4 / 5 VAL A 322
VAL A 176
ARG A 175
LYS A 293
 None
 1.33A 3rv5A-3ozqA:
undetectable
3rv5B-3ozqA:
undetectable		 3rv5A-3ozqA:
14.24
3rv5B-3ozqA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_A_SASA806_1
(SEPIAPTERIN
REDUCTASE)		 3ozq SERPIN48
(Tenebrio
molitor) 		5 / 12 LEU A  94
PHE A  52
GLN A  22
MET A 378
GLY A 377
 None
 1.43A 4j7xA-3ozqA:
undetectable		 4j7xA-3ozqA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_F_SASF805_1
(SEPIAPTERIN
REDUCTASE)		 3ozq SERPIN48
(Tenebrio
molitor) 		5 / 12 LEU A  94
PHE A  52
GLN A  22
MET A 378
GLY A 377
 None
 1.41A 4j7xF-3ozqA:
undetectable		 4j7xF-3ozqA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ozq SERPIN48
(Tenebrio
molitor) 		3 / 3 LEU A 256
TYR A  36
SER A 266
 None
 0.86A 5iktA-3ozqA:
undetectable		 5iktA-3ozqA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3ozq SERPIN48
(Tenebrio
molitor) 		4 / 5 LEU A 170
LYS A 142
ALA A 145
LEU A 148
 None
 0.86A 5vkqB-3ozqA:
undetectable
5vkqC-3ozqA:
undetectable		 5vkqB-3ozqA:
12.15
5vkqC-3ozqA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_A_ECLA1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 3ozq SERPIN48
(Tenebrio
molitor) 		4 / 7 ILE A  73
PHE A  31
LEU A  77
ILE A 125
 None
 0.77A 6b5vA-3ozqA:
undetectable
6b5vC-3ozqA:
undetectable		 6b5vA-3ozqA:
13.91
6b5vC-3ozqA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_C_ECLC1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 3ozq SERPIN48
(Tenebrio
molitor) 		4 / 7 ILE A  73
PHE A  31
LEU A  77
ILE A 125
 None
 0.77A 6b5vC-3ozqA:
undetectable
6b5vD-3ozqA:
undetectable		 6b5vC-3ozqA:
13.91
6b5vD-3ozqA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_D_ECLD1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 3ozq SERPIN48
(Tenebrio
molitor) 		4 / 7 ILE A  73
PHE A  31
LEU A  77
ILE A 125
 None
 0.76A 6b5vB-3ozqA:
undetectable
6b5vD-3ozqA:
undetectable		 6b5vB-3ozqA:
13.91
6b5vD-3ozqA:
13.91