SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3p02'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_D_NIOD223_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3p02 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 5 PHE A 297
GLY A 219
SER A 302
THR A 301
 None
EDO  A   3 (-4.5A)
EDO  A   3 ( 4.3A)
None
 1.25A 1icuC-3p02A:
undetectable
1icuD-3p02A:
undetectable		 1icuC-3p02A:
19.25
1icuD-3p02A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_B_NIOB702_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3p02 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 5 PHE A 297
GLY A 219
SER A 302
THR A 301
 None
EDO  A   3 (-4.5A)
EDO  A   3 ( 4.3A)
None
 1.21A 1icvA-3p02A:
undetectable
1icvB-3p02A:
undetectable		 1icvA-3p02A:
19.25
1icvB-3p02A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J3J_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3p02 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 10 ASP A 227
SER A 201
ILE A 204
TYR A 310
THR A 301
 None
 1.29A 1j3jA-3p02A:
undetectable		 1j3jA-3p02A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J3J_B_CP6B709_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3p02 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 9 ASP A 227
SER A 201
ILE A 204
TYR A 310
THR A 301
 None
 1.28A 1j3jB-3p02A:
undetectable		 1j3jB-3p02A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_2
(POL POLYPROTEIN)		 3p02 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 10 ARG A 221
GLY A 184
ILE A 197
GLY A 314
ILE A 293
 EDO  A   3 (-4.1A)
None
None
None
None
 0.99A 1sh9B-3p02A:
undetectable		 1sh9B-3p02A:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1499_1
(CYTOCHROME P450 3A4)		 3p02 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 7 SER A 264
LEU A 187
ILE A 253
GLY A 189
 None
 0.96A 2v0mC-3p02A:
undetectable		 2v0mC-3p02A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1160_1
(ALLERGEN ARG R 1)		 3p02 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 6 SER A 302
TYR A 231
TYR A 225
ASP A 299
 EDO  A   3 ( 4.3A)
None
None
EDO  A   3 ( 4.9A)
 1.22A 2x45A-3p02A:
undetectable		 2x45A-3p02A:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1160_1
(ALLERGEN ARG R 1)		 3p02 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 7 SER A 302
TYR A 231
TYR A 225
ASP A 299
 EDO  A   3 ( 4.3A)
None
None
EDO  A   3 ( 4.9A)
 1.22A 2x45B-3p02A:
1.4		 2x45B-3p02A:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1160_1
(ALLERGEN ARG R 1)		 3p02 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 7 SER A 302
TYR A 231
TYR A 225
ASP A 299
 EDO  A   3 ( 4.3A)
None
None
EDO  A   3 ( 4.9A)
 1.23A 2x45C-3p02A:
undetectable		 2x45C-3p02A:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_G_SAMG226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3p02 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 12 GLY A 315
ASP A 292
GLY A 184
LEU A 206
ILE A 204
 None
 1.13A 3ku1G-3p02A:
undetectable		 3ku1G-3p02A:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QG2_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3p02 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 10 ASP A 227
SER A 201
ILE A 204
TYR A 310
THR A 301
 None
 1.30A 3qg2A-3p02A:
undetectable		 3qg2A-3p02A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UM5_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3p02 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 10 ASP A 227
SER A 201
ILE A 204
TYR A 310
THR A 301
 None
 1.24A 3um5A-3p02A:
undetectable		 3um5A-3p02A:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UM5_B_CP6B709_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3p02 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 10 ASP A 227
SER A 201
ILE A 204
TYR A 310
THR A 301
 None
 1.23A 3um5B-3p02A:
undetectable		 3um5B-3p02A:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA602_1
(SERUM ALBUMIN)		 3p02 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 6 ARG A 171
ALA A 144
ASP A  47
LEU A  87
 None
 1.13A 4ot2A-3p02A:
undetectable		 4ot2A-3p02A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_E_ACTE403_0
(PROTON-GATED ION
CHANNEL)		 3p02 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		3 / 3 ARG A  76
TYR A 157
GLU A 151
 None
 0.56A 4zzbE-3p02A:
undetectable		 4zzbE-3p02A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB306_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3p02 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 4 LEU A 316
GLY A 315
SER A 186
SER A 185
 None
 1.31A 5uunB-3p02A:
undetectable		 5uunB-3p02A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_2
(PROTEASE)		 3p02 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		3 / 3 LEU A 188
ASP A 292
ILE A 290
 None
 0.65A 6dh0B-3p02A:
undetectable		 6dh0B-3p02A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_A_LLLA301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3p02 UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 6 TYR A  58
GLU A 329
ASP A 328
GLU A 177
 None
 1.45A 6mn5A-3p02A:
undetectable		 6mn5A-3p02A:
15.30