SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3p09'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_1
(BETA-LACTAMASE)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		7 / 12 SER A  61
LYS A  64
SER A 122
GLU A 158
THR A 208
LYS A 226
GLY A 228
 SO4  A 288 (-3.1A)
None
SO4  A 288 (-2.7A)
None
SO4  A 288 ( 4.8A)
SO4  A 288 (-3.5A)
SO4  A 288 (-3.3A)
 0.38A 1i2wA-3p09A:
39.1		 1i2wA-3p09A:
29.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_B_CFXB2300_1
(BETA-LACTAMASE)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		6 / 12 SER A  61
LYS A  64
SER A 122
GLU A 158
GLY A 228
ARG A 212
 SO4  A 288 (-3.1A)
None
SO4  A 288 (-2.7A)
None
SO4  A 288 (-3.3A)
SO4  A 288 ( 4.4A)
 1.12A 1i2wB-3p09A:
39.5		 1i2wB-3p09A:
29.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_B_CFXB2300_1
(BETA-LACTAMASE)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		6 / 12 SER A  61
LYS A  64
SER A 122
GLU A 158
THR A 208
GLY A 228
 SO4  A 288 (-3.1A)
None
SO4  A 288 (-2.7A)
None
SO4  A 288 ( 4.8A)
SO4  A 288 (-3.3A)
 0.38A 1i2wB-3p09A:
39.5		 1i2wB-3p09A:
29.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQ5_D_PAUD6004_0
(PANTOTHENATE KINASE)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		5 / 10 VAL A  68
LEU A  67
TYR A 202
ILE A 112
ASN A 116
 None
 1.43A 1sq5D-3p09A:
undetectable		 1sq5D-3p09A:
23.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YMX_A_CFXA1001_1
(BETA-LACTAMASE
CTX-M-9)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		8 / 12 SER A  61
LYS A  64
SER A 122
GLU A 158
ASN A 162
THR A 208
LYS A 226
GLY A 228
 SO4  A 288 (-3.1A)
None
SO4  A 288 (-2.7A)
None
None
SO4  A 288 ( 4.8A)
SO4  A 288 (-3.5A)
SO4  A 288 (-3.3A)
 0.67A 1ymxA-3p09A:
39.5		 1ymxA-3p09A:
31.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YMX_B_CFXB1002_1
(BETA-LACTAMASE
CTX-M-9)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		7 / 12 SER A  61
LYS A  64
SER A 122
GLU A 158
ASN A 162
LYS A 226
GLY A 228
 SO4  A 288 (-3.1A)
None
SO4  A 288 (-2.7A)
None
None
SO4  A 288 (-3.5A)
SO4  A 288 (-3.3A)
 0.63A 1ymxB-3p09A:
39.7		 1ymxB-3p09A:
31.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YMX_B_CFXB1002_2
(BETA-LACTAMASE
CTX-M-9)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		4 / 5 TYR A  98
PRO A 159
THR A 208
THR A 227
 None
None
SO4  A 288 ( 4.8A)
SO4  A 288 (-3.6A)
 0.76A 1ymxB-3p09A:
39.7		 1ymxB-3p09A:
31.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H4J_A_NCAA1002_0
(NAD-DEPENDENT
DEACETYLASE)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		4 / 5 ALA A 126
ILE A  88
ILE A  93
ASP A  92
 None
 1.09A 2h4jA-3p09A:
undetectable		 2h4jA-3p09A:
22.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HLW_A_CE3A301_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		6 / 12 LYS A  64
SER A 122
ASN A 162
THR A 208
LYS A 226
GLY A 228
 None
SO4  A 288 (-2.7A)
None
SO4  A 288 ( 4.8A)
SO4  A 288 (-3.5A)
SO4  A 288 (-3.3A)
 0.60A 3hlwA-3p09A:
39.4		 3hlwA-3p09A:
30.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HLW_A_CE3A301_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		6 / 12 LYS A  64
TYR A  98
SER A 122
THR A 208
LYS A 226
GLY A 228
 None
None
SO4  A 288 (-2.7A)
SO4  A 288 ( 4.8A)
SO4  A 288 (-3.5A)
SO4  A 288 (-3.3A)
 0.62A 3hlwA-3p09A:
39.4		 3hlwA-3p09A:
30.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HLW_B_CE3B302_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		6 / 12 SER A 122
ASN A 162
THR A 208
LYS A 226
THR A 227
GLY A 228
 SO4  A 288 (-2.7A)
None
SO4  A 288 ( 4.8A)
SO4  A 288 (-3.5A)
SO4  A 288 (-3.6A)
SO4  A 288 (-3.3A)
 0.49A 3hlwB-3p09A:
39.6		 3hlwB-3p09A:
30.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HLW_B_CE3B302_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		6 / 12 TYR A  98
SER A 122
THR A 208
LYS A 226
THR A 227
GLY A 228
 None
SO4  A 288 (-2.7A)
SO4  A 288 ( 4.8A)
SO4  A 288 (-3.5A)
SO4  A 288 (-3.6A)
SO4  A 288 (-3.3A)
 0.57A 3hlwB-3p09A:
39.6		 3hlwB-3p09A:
30.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HUO_A_PNNA300_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		5 / 12 LYS A  64
ASN A 162
LYS A 226
THR A 227
GLY A 228
 None
None
SO4  A 288 (-3.5A)
SO4  A 288 (-3.6A)
SO4  A 288 (-3.3A)
 0.48A 3huoA-3p09A:
39.4		 3huoA-3p09A:
30.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		5 / 12 ASP A  92
VAL A  68
ALA A 126
ALA A 119
ASP A 123
 None
 1.08A 3keeC-3p09A:
undetectable		 3keeC-3p09A:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LPS_A_NOVA901_1
(TOPOISOMERASE IV
SUBUNIT B)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		5 / 12 ASP A 281
MET A 217
PRO A 218
ASP A 220
ILE A 242
 None
 1.40A 3lpsA-3p09A:
undetectable		 3lpsA-3p09A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		6 / 12 SER A  61
LYS A  64
GLY A  97
THR A 227
GLY A 228
ARG A 212
 SO4  A 288 (-3.1A)
None
None
SO4  A 288 (-3.6A)
SO4  A 288 (-3.3A)
SO4  A 288 ( 4.4A)
 1.14A 3mzeA-3p09A:
21.7		 3mzeA-3p09A:
18.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NY4_A_SMXA308_1
(BETA-LACTAMASE)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		9 / 12 SER A  61
SER A 122
ASN A 162
THR A 208
ARG A 212
LYS A 226
THR A 227
GLY A 228
THR A 229
 SO4  A 288 (-3.1A)
SO4  A 288 (-2.7A)
None
SO4  A 288 ( 4.8A)
SO4  A 288 ( 4.4A)
SO4  A 288 (-3.5A)
SO4  A 288 (-3.6A)
SO4  A 288 (-3.3A)
SO4  A 288 (-3.4A)
 0.45A 3ny4A-3p09A:
38.6		 3ny4A-3p09A:
32.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		5 / 12 LYS A  64
SER A 122
ASN A 162
LYS A 226
GLY A 228
 None
SO4  A 288 (-2.7A)
None
SO4  A 288 (-3.5A)
SO4  A 288 (-3.3A)
 0.44A 3q07A-3p09A:
39.5		 3q07A-3p09A:
30.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		5 / 12 LYS A  64
SER A 122
ASN A 162
LYS A 226
GLY A 228
 None
SO4  A 288 (-2.7A)
None
SO4  A 288 (-3.5A)
SO4  A 288 (-3.3A)
 0.56A 3q07B-3p09A:
39.8		 3q07B-3p09A:
30.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		6 / 12 SER A  61
TYR A  98
SER A 122
LYS A 226
THR A 227
GLY A 228
 SO4  A 288 (-3.1A)
None
SO4  A 288 (-2.7A)
SO4  A 288 (-3.5A)
SO4  A 288 (-3.6A)
SO4  A 288 (-3.3A)
 0.53A 3sh8A-3p09A:
37.7		 3sh8A-3p09A:
28.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		5 / 11 ILE A 250
ILE A 223
ILE A 278
ALA A 214
PRO A 244
 None
 1.04A 3tmzA-3p09A:
undetectable		 3tmzA-3p09A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_B_LOCB502_1
(TUBULIN BETA CHAIN)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		5 / 12 ALA A 118
ALA A 103
ILE A  88
LYS A 104
ILE A  93
 None
 1.03A 3ut5B-3p09A:
undetectable		 3ut5B-3p09A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		4 / 8 ASN A 162
GLU A 160
ILE A 161
ASN A 128
 None
 0.99A 4d33A-3p09A:
undetectable		 4d33A-3p09A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		4 / 7 ASN A 162
GLU A 160
ILE A 161
ASN A 128
 None
 1.03A 4d33B-3p09A:
undetectable		 4d33B-3p09A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		4 / 8 ASN A 162
GLU A 160
ILE A 161
ASN A 128
 None
 1.03A 4d39A-3p09A:
undetectable		 4d39A-3p09A:
20.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EUZ_A_MEMA401_1
(CARBAPENEM-HYDROLIZI
NG BETA-LACTAMASE
SFC-1)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		8 / 12 LYS A  64
SER A 122
ASN A 162
THR A 208
LYS A 226
THR A 227
GLY A 228
THR A 229
 None
SO4  A 288 (-2.7A)
None
SO4  A 288 ( 4.8A)
SO4  A 288 (-3.5A)
SO4  A 288 (-3.6A)
SO4  A 288 (-3.3A)
SO4  A 288 (-3.4A)
 0.34A 4euzA-3p09A:
39.6		 4euzA-3p09A:
32.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FH2_A_0RNA303_1
(BETA-LACTAMASE SHV-1)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		5 / 10 TYR A  98
SER A 122
LYS A 226
THR A 227
GLY A 228
 None
SO4  A 288 (-2.7A)
SO4  A 288 (-3.5A)
SO4  A 288 (-3.6A)
SO4  A 288 (-3.3A)
 0.76A 4fh2A-3p09A:
33.6		 4fh2A-3p09A:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_C_SVRC301_1
(NUCLEOCAPSID PROTEIN)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		4 / 8 GLY A 135
ASN A 139
PHE A  81
ILE A  71
 None
 0.94A 4j4vC-3p09A:
undetectable		 4j4vC-3p09A:
24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		7 / 12 SER A  61
TYR A  98
SER A 122
ASN A 162
LYS A 226
THR A 227
GLY A 228
 SO4  A 288 (-3.1A)
None
SO4  A 288 (-2.7A)
None
SO4  A 288 (-3.5A)
SO4  A 288 (-3.6A)
SO4  A 288 (-3.3A)
 0.53A 4n9kA-3p09A:
39.2		 4n9kA-3p09A:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		6 / 12 SER A  61
SER A 122
ASN A 162
LYS A 226
THR A 227
GLY A 228
 SO4  A 288 (-3.1A)
SO4  A 288 (-2.7A)
None
SO4  A 288 (-3.5A)
SO4  A 288 (-3.6A)
SO4  A 288 (-3.3A)
 0.27A 4n9kB-3p09A:
39.1		 4n9kB-3p09A:
28.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM5_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		7 / 12 TYR A  98
SER A 122
ASN A 162
THR A 208
LYS A 226
THR A 227
GLY A 228
 None
SO4  A 288 (-2.7A)
None
SO4  A 288 ( 4.8A)
SO4  A 288 (-3.5A)
SO4  A 288 (-3.6A)
SO4  A 288 (-3.3A)
 0.92A 4pm5A-3p09A:
39.4		 4pm5A-3p09A:
30.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM7_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		7 / 12 LYS A  64
TYR A  98
SER A 122
ASN A 162
THR A 208
LYS A 226
GLY A 228
 None
None
SO4  A 288 (-2.7A)
None
SO4  A 288 ( 4.8A)
SO4  A 288 (-3.5A)
SO4  A 288 (-3.3A)
 0.98A 4pm7A-3p09A:
39.4		 4pm7A-3p09A:
30.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM9_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		7 / 12 TYR A  98
SER A 122
ASN A 162
THR A 208
LYS A 226
THR A 227
GLY A 228
 None
SO4  A 288 (-2.7A)
None
SO4  A 288 ( 4.8A)
SO4  A 288 (-3.5A)
SO4  A 288 (-3.6A)
SO4  A 288 (-3.3A)
 0.89A 4pm9A-3p09A:
39.3		 4pm9A-3p09A:
30.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C8T_B_SAMB605_0
(GUANINE-N7
METHYLTRANSFERASE)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		5 / 11 GLY A  34
PRO A 259
ALA A 234
TYR A  32
ASN A  52
 None
 1.31A 5c8tB-3p09A:
undetectable		 5c8tB-3p09A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_B_0HKB1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		3 / 3 ASP A 225
ASN A 237
PHE A  63
 None
 0.66A 5dsgB-3p09A:
undetectable		 5dsgB-3p09A:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		5 / 12 SER A  61
SER A 122
ASN A 162
LYS A 226
GLY A 228
 SO4  A 288 (-3.1A)
SO4  A 288 (-2.7A)
None
SO4  A 288 (-3.5A)
SO4  A 288 (-3.3A)
 0.34A 5ghyA-3p09A:
39.0		 5ghyA-3p09A:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		5 / 12 SER A  61
SER A 122
ASN A 162
LYS A 226
GLY A 228
 SO4  A 288 (-3.1A)
SO4  A 288 (-2.7A)
None
SO4  A 288 (-3.5A)
SO4  A 288 (-3.3A)
 0.30A 5ghyB-3p09A:
39.0		 5ghyB-3p09A:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		7 / 11 SER A  61
TYR A  98
SER A 122
ASN A 162
LYS A 226
THR A 227
GLY A 228
 SO4  A 288 (-3.1A)
None
SO4  A 288 (-2.7A)
None
SO4  A 288 (-3.5A)
SO4  A 288 (-3.6A)
SO4  A 288 (-3.3A)
 0.59A 5ghzA-3p09A:
38.9		 5ghzA-3p09A:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		7 / 10 SER A  61
TYR A  98
SER A 122
ASN A 162
LYS A 226
THR A 227
GLY A 228
 SO4  A 288 (-3.1A)
None
SO4  A 288 (-2.7A)
None
SO4  A 288 (-3.5A)
SO4  A 288 (-3.6A)
SO4  A 288 (-3.3A)
 0.57A 5ghzB-3p09A:
38.9		 5ghzB-3p09A:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		3 / 3 ASP A 149
ASN A 141
PHE A  57
 None
 0.85A 5jglB-3p09A:
undetectable		 5jglB-3p09A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		5 / 12 ILE A 154
LEU A 137
GLY A  69
ALA A  70
LEU A 134
 None
SO4  A 294 (-4.5A)
None
None
None
 1.17A 5zwrA-3p09A:
15.3		 5zwrA-3p09A:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		9 / 12 SER A  61
SER A 122
ASN A 162
THR A 208
ARG A 212
LYS A 226
THR A 227
GLY A 228
THR A 229
 SO4  A 288 (-3.1A)
SO4  A 288 (-2.7A)
None
SO4  A 288 ( 4.8A)
SO4  A 288 ( 4.4A)
SO4  A 288 (-3.5A)
SO4  A 288 (-3.6A)
SO4  A 288 (-3.3A)
SO4  A 288 (-3.4A)
 0.40A 6b5yB-3p09A:
39.2		 6b5yB-3p09A:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		9 / 12 SER A  61
SER A 122
ASN A 162
THR A 208
LYS A 226
THR A 227
GLY A 228
THR A 229
GLU A 268
 SO4  A 288 (-3.1A)
SO4  A 288 (-2.7A)
None
SO4  A 288 ( 4.8A)
SO4  A 288 (-3.5A)
SO4  A 288 (-3.6A)
SO4  A 288 (-3.3A)
SO4  A 288 (-3.4A)
None
 0.45A 6b5yD-3p09A:
39.3		 6b5yD-3p09A:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		8 / 12 SER A  61
SER A 122
ASN A 162
THR A 208
LYS A 226
THR A 227
GLY A 228
THR A 229
 SO4  A 288 (-3.1A)
SO4  A 288 (-2.7A)
None
SO4  A 288 ( 4.8A)
SO4  A 288 (-3.5A)
SO4  A 288 (-3.6A)
SO4  A 288 (-3.3A)
SO4  A 288 (-3.4A)
 0.28A 6b68B-3p09A:
39.3		 6b68B-3p09A:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		9 / 12 SER A  61
SER A 122
ASN A 162
THR A 208
ARG A 212
LYS A 226
GLY A 228
THR A 229
GLU A 268
 SO4  A 288 (-3.1A)
SO4  A 288 (-2.7A)
None
SO4  A 288 ( 4.8A)
SO4  A 288 ( 4.4A)
SO4  A 288 (-3.5A)
SO4  A 288 (-3.3A)
SO4  A 288 (-3.4A)
None
 0.33A 6b68D-3p09A:
39.3		 6b68D-3p09A:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		9 / 12 SER A  61
SER A 122
PRO A 159
ASN A 162
THR A 208
LYS A 226
THR A 227
GLY A 228
THR A 229
 SO4  A 288 (-3.1A)
SO4  A 288 (-2.7A)
None
None
SO4  A 288 ( 4.8A)
SO4  A 288 (-3.5A)
SO4  A 288 (-3.6A)
SO4  A 288 (-3.3A)
SO4  A 288 (-3.4A)
 0.29A 6b69A-3p09A:
39.2
6b69B-3p09A:
39.3		 6b69A-3p09A:
25.37
6b69B-3p09A:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		10 / 12 SER A  61
SER A 122
ASN A 162
THR A 208
ARG A 212
LYS A 226
THR A 227
GLY A 228
THR A 229
GLU A 268
 SO4  A 288 (-3.1A)
SO4  A 288 (-2.7A)
None
SO4  A 288 ( 4.8A)
SO4  A 288 ( 4.4A)
SO4  A 288 (-3.5A)
SO4  A 288 (-3.6A)
SO4  A 288 (-3.3A)
SO4  A 288 (-3.4A)
None
 0.28A 6b69D-3p09A:
39.3		 6b69D-3p09A:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		9 / 12 SER A  61
SER A 122
ASN A 162
THR A 208
ARG A 212
LYS A 226
THR A 227
GLY A 228
THR A 229
 SO4  A 288 (-3.1A)
SO4  A 288 (-2.7A)
None
SO4  A 288 ( 4.8A)
SO4  A 288 ( 4.4A)
SO4  A 288 (-3.5A)
SO4  A 288 (-3.6A)
SO4  A 288 (-3.3A)
SO4  A 288 (-3.4A)
 0.30A 6b6aB-3p09A:
39.1		 6b6aB-3p09A:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		9 / 12 SER A  61
SER A 122
ASN A 162
ARG A 212
LYS A 226
THR A 227
GLY A 228
THR A 229
GLU A 268
 SO4  A 288 (-3.1A)
SO4  A 288 (-2.7A)
None
SO4  A 288 ( 4.4A)
SO4  A 288 (-3.5A)
SO4  A 288 (-3.6A)
SO4  A 288 (-3.3A)
SO4  A 288 (-3.4A)
None
 0.32A 6b6aD-3p09A:
39.1		 6b6aD-3p09A:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		9 / 12 SER A  61
SER A 122
PRO A 159
ASN A 162
ARG A 212
LYS A 226
THR A 227
GLY A 228
THR A 229
 SO4  A 288 (-3.1A)
SO4  A 288 (-2.7A)
None
None
SO4  A 288 ( 4.4A)
SO4  A 288 (-3.5A)
SO4  A 288 (-3.6A)
SO4  A 288 (-3.3A)
SO4  A 288 (-3.4A)
 0.40A 6b6cA-3p09A:
38.9		 6b6cA-3p09A:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		8 / 12 SER A  61
SER A 122
ASN A 162
THR A 208
LYS A 226
THR A 227
GLY A 228
THR A 229
 SO4  A 288 (-3.1A)
SO4  A 288 (-2.7A)
None
SO4  A 288 ( 4.8A)
SO4  A 288 (-3.5A)
SO4  A 288 (-3.6A)
SO4  A 288 (-3.3A)
SO4  A 288 (-3.4A)
 0.53A 6b6dA-3p09A:
38.9		 6b6dA-3p09A:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		9 / 12 SER A  61
SER A 122
ASN A 162
THR A 208
ARG A 212
LYS A 226
THR A 227
GLY A 228
THR A 229
 SO4  A 288 (-3.1A)
SO4  A 288 (-2.7A)
None
SO4  A 288 ( 4.8A)
SO4  A 288 ( 4.4A)
SO4  A 288 (-3.5A)
SO4  A 288 (-3.6A)
SO4  A 288 (-3.3A)
SO4  A 288 (-3.4A)
 0.31A 6b6eA-3p09A:
39.0		 6b6eA-3p09A:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		9 / 12 CSS A  60
SER A  61
SER A 122
PRO A 159
ASN A 162
LYS A 226
THR A 227
GLY A 228
THR A 229
 None
SO4  A 288 (-3.1A)
SO4  A 288 (-2.7A)
None
None
SO4  A 288 (-3.5A)
SO4  A 288 (-3.6A)
SO4  A 288 (-3.3A)
SO4  A 288 (-3.4A)
 0.51A 6b6fA-3p09A:
38.8		 6b6fA-3p09A:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		6 / 12 CSS A 230
PRO A 159
ASN A 162
THR A 227
GLY A 228
THR A 229
 None
None
None
SO4  A 288 (-3.6A)
SO4  A 288 (-3.3A)
SO4  A 288 (-3.4A)
 1.41A 6b6fA-3p09A:
38.8		 6b6fA-3p09A:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C79_A_CE3A301_1
(BETA-LACTAMASE
TOHO-1)		 3p09 BETA-LACTAMASE
(Francisella
tularensis) 		6 / 12 TYR A  98
SER A 122
ASN A 162
THR A 208
LYS A 226
GLY A 228
 None
SO4  A 288 (-2.7A)
None
SO4  A 288 ( 4.8A)
SO4  A 288 (-3.5A)
SO4  A 288 (-3.3A)
 0.77A 6c79A-3p09A:
39.8		 6c79A-3p09A:
13.84