SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3p0t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6K_A_ADNA699_1
(CHLORINASE)		 3p0t UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		4 / 7 ASP A 104
PHE A  97
PRO A  98
THR A  77
 None
 1.48A 2q6kA-3p0tA:
undetectable		 2q6kA-3p0tA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 3p0t UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		5 / 10 LEU A 130
ILE A  67
SER A  80
LYS A  69
GLY A  68
 None
 1.28A 3ik6B-3p0tA:
undetectable
3ik6E-3p0tA:
undetectable		 3ik6B-3p0tA:
21.97
3ik6E-3p0tA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_E_HFZE800_1
(GLUTAMATE RECEPTOR 2)		 3p0t UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		5 / 11 ILE A  67
SER A  80
LYS A  69
GLY A  68
LEU A 130
 None
 1.31A 3iluB-3p0tA:
undetectable
3iluE-3p0tA:
undetectable		 3iluB-3p0tA:
21.97
3iluE-3p0tA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_A_OBNA1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3p0t UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		5 / 11 PRO A  32
VAL A  71
ALA A  70
THR A  38
ILE A  67
 None
 1.29A 3n23A-3p0tA:
undetectable		 3n23A-3p0tA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O1X_A_ADNA1450_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 3p0t UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		5 / 10 PHE A   5
ILE A   8
LEU A  39
HIS A  93
HIS A  95
 None
EDO  A 201 ( 4.8A)
None
SO4  A 150 (-3.8A)
SO4  A 150 (-4.1A)
 1.30A 3o1xA-3p0tA:
11.3		 3o1xA-3p0tA:
26.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGZ_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 3p0t UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		5 / 10 PHE A   5
ILE A   8
LEU A  39
HIS A  93
HIS A  95
 None
EDO  A 201 ( 4.8A)
None
SO4  A 150 (-3.8A)
SO4  A 150 (-4.1A)
 1.30A 3qgzA-3p0tA:
11.4		 3qgzA-3p0tA:
26.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGZ_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 3p0t UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		5 / 10 PHE A   5
ILE A  30
LEU A  39
HIS A  93
HIS A  95
 None
EDO  A 200 (-3.9A)
None
SO4  A 150 (-3.8A)
SO4  A 150 (-4.1A)
 1.09A 3qgzA-3p0tA:
11.4		 3qgzA-3p0tA:
26.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KM9_B_ADNB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)		 3p0t UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		5 / 12 ILE A   4
ILE A   8
LEU A  39
HIS A  93
HIS A  95
 None
EDO  A 201 ( 4.8A)
None
SO4  A 150 (-3.8A)
SO4  A 150 (-4.1A)
 0.69A 5km9B-3p0tA:
12.2		 5km9B-3p0tA:
27.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KM9_B_ADNB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)		 3p0t UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		5 / 12 ILE A   8
LEU A  39
VAL A  89
HIS A  93
HIS A  95
 EDO  A 201 ( 4.8A)
None
SO4  A 150 (-4.2A)
SO4  A 150 (-3.8A)
SO4  A 150 (-4.1A)
 0.54A 5km9B-3p0tA:
12.2		 5km9B-3p0tA:
27.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UVM_B_ADNB207_1
(HISTIDINE TRIAD
(HIT) PROTEIN)		 3p0t UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		6 / 12 PHE A   5
ILE A   8
LEU A  39
VAL A  89
HIS A  93
HIS A  95
 None
EDO  A 201 ( 4.8A)
None
SO4  A 150 (-4.2A)
SO4  A 150 (-3.8A)
SO4  A 150 (-4.1A)
 1.13A 5uvmB-3p0tA:
11.6		 5uvmB-3p0tA:
30.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UVM_B_ADNB207_1
(HISTIDINE TRIAD
(HIT) PROTEIN)		 3p0t UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		6 / 12 PHE A   5
ILE A   9
LEU A  39
VAL A  89
HIS A  93
HIS A  95
 None
None
None
SO4  A 150 (-4.2A)
SO4  A 150 (-3.8A)
SO4  A 150 (-4.1A)
 1.40A 5uvmB-3p0tA:
11.6		 5uvmB-3p0tA:
30.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UVM_B_ADNB207_1
(HISTIDINE TRIAD
(HIT) PROTEIN)		 3p0t UNCHARACTERIZED
PROTEIN
(Mycobacterium
avium) 		6 / 12 PHE A   5
ILE A  30
LEU A  39
VAL A  89
HIS A  93
HIS A  95
 None
EDO  A 200 (-3.9A)
None
SO4  A 150 (-4.2A)
SO4  A 150 (-3.8A)
SO4  A 150 (-4.1A)
 0.98A 5uvmB-3p0tA:
11.6		 5uvmB-3p0tA:
30.46