SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3p0w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHI_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		5 / 12 ILE A 239
ALA A 237
LEU A 250
LYS A 221
ILE A 204
 None
None
None
GKR  A 472 (-3.0A)
None
 1.02A 1dhiA-3p0wA:
undetectable		 1dhiA-3p0wA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHI_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		5 / 11 ILE A 239
ALA A 237
LEU A 250
LYS A 221
ILE A 204
 None
None
None
GKR  A 472 (-3.0A)
None
 1.02A 1dhiB-3p0wA:
undetectable		 1dhiB-3p0wA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHJ_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		5 / 12 ILE A 239
ALA A 237
LEU A 250
LYS A 221
ILE A 204
 None
None
None
GKR  A 472 (-3.0A)
None
 1.03A 1dhjB-3p0wA:
undetectable		 1dhjB-3p0wA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRA_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		5 / 12 ILE A 239
ALA A 237
LEU A 250
LYS A 221
ILE A 204
 None
None
None
GKR  A 472 (-3.0A)
None
 1.02A 1draA-3p0wA:
undetectable		 1draA-3p0wA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRA_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		5 / 12 ILE A 239
ALA A 237
LEU A 250
LYS A 221
ILE A 204
 None
None
None
GKR  A 472 (-3.0A)
None
 1.01A 1draB-3p0wA:
undetectable		 1draB-3p0wA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		5 / 10 ILE A 239
ALA A 237
LEU A 250
LYS A 221
ILE A 204
 None
None
None
GKR  A 472 (-3.0A)
None
 0.95A 1rb3A-3p0wA:
undetectable		 1rb3A-3p0wA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RD7_B_FOLB361_0
(DIHYDROFOLATE
REDUCTASE)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		5 / 12 ILE A 239
ALA A 237
LEU A 250
LYS A 221
ILE A 204
 None
None
None
GKR  A 472 (-3.0A)
None
 1.03A 1rd7B-3p0wA:
undetectable		 1rd7B-3p0wA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRC_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		5 / 12 ILE A 239
ALA A 237
LEU A 250
LYS A 221
ILE A 204
 None
None
None
GKR  A 472 (-3.0A)
None
 0.99A 2drcA-3p0wA:
undetectable		 2drcA-3p0wA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRC_B_MTXB161_1
(DIHYDROFOLATE
REDUCTASE)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		5 / 12 ILE A 239
ALA A 237
LEU A 250
LYS A 221
ILE A 204
 None
None
None
GKR  A 472 (-3.0A)
None
 0.95A 2drcB-3p0wA:
undetectable		 2drcB-3p0wA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KUH_A_HLTA150_1
(CALMODULIN)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		4 / 6 LEU A 447
LEU A 460
MET A 444
MET A  24
 None
 1.29A 2kuhA-3p0wA:
undetectable		 2kuhA-3p0wA:
10.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DRC_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		5 / 12 ILE A 239
ALA A 237
LEU A 250
LYS A 221
ILE A 204
 None
None
None
GKR  A 472 (-3.0A)
None
 1.00A 3drcA-3p0wA:
undetectable		 3drcA-3p0wA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DRC_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		5 / 12 ILE A 239
ALA A 237
LEU A 250
LYS A 221
ILE A 204
 None
None
None
GKR  A 472 (-3.0A)
None
 0.97A 3drcB-3p0wA:
undetectable		 3drcB-3p0wA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_DXCC576_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		4 / 8 PRO A 201
ALA A 205
ALA A 208
GLU A 234
 None
 0.76A 3dtuC-3p0wA:
undetectable
3dtuD-3p0wA:
undetectable		 3dtuC-3p0wA:
23.96
3dtuD-3p0wA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_B_VORB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		6 / 11 VAL A 341
ILE A 325
ALA A 328
ALA A 308
ALA A 303
THR A 304
 None
 1.22A 3mdtB-3p0wA:
undetectable		 3mdtB-3p0wA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL3_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		5 / 12 ILE A 239
ALA A 237
LEU A 250
LYS A 221
ILE A 204
 None
None
None
GKR  A 472 (-3.0A)
None
 1.15A 3ql3A-3p0wA:
undetectable		 3ql3A-3p0wA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQ9_A_MTXA2001_1
(DIHYDROFOLATE
REDUCTASE)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		5 / 12 ILE A 239
ALA A 237
LEU A 250
LYS A 221
ILE A 204
 None
None
None
GKR  A 472 (-3.0A)
None
 1.04A 3tq9A-3p0wA:
undetectable		 3tq9A-3p0wA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I1R_A_LZUA801_1
(MUCOSA-ASSOCIATED
LYMPHOID TISSUE
LYMPHOMA
TRANSLOCATION
PROTEIN 1)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		5 / 12 VAL A 339
ALA A 134
LEU A 151
LEU A 152
LEU A  84
 None
 1.15A 4i1rA-3p0wA:
undetectable		 4i1rA-3p0wA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		4 / 8 HIS A 331
PRO A 330
ASP A 329
SER A 354
 None
 1.02A 4k0bB-3p0wA:
undetectable		 4k0bB-3p0wA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		4 / 8 HIS A 331
PRO A 330
ASP A 329
SER A 354
 None
 0.99A 4l7iB-3p0wA:
undetectable		 4l7iB-3p0wA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA604_1
(TRANSPORTER)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		4 / 7 ARG A 242
LEU A 193
ASP A 189
THR A 212
 None
 1.09A 4mmcA-3p0wA:
undetectable		 4mmcA-3p0wA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_H_9CRH501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		5 / 12 ALA A 373
ALA A 374
GLN A 157
LEU A 152
HIS A 355
 None
 1.13A 4nqaH-3p0wA:
undetectable		 4nqaH-3p0wA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_C_IPHC101_0
(INSULIN)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		5 / 11 LEU A 136
ALA A 135
LEU A  43
VAL A  68
LEU A  65
 None
 1.15A 4p65C-3p0wA:
undetectable
4p65D-3p0wA:
undetectable
4p65J-3p0wA:
undetectable
4p65L-3p0wA:
undetectable		 4p65C-3p0wA:
4.03
4p65D-3p0wA:
11.32
4p65J-3p0wA:
11.32
4p65L-3p0wA:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P66_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		5 / 11 ILE A 239
ALA A 237
LEU A 250
LYS A 221
ILE A 204
 None
None
None
GKR  A 472 (-3.0A)
None
 1.00A 4p66A-3p0wA:
undetectable		 4p66A-3p0wA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_A_HISA302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		5 / 10 VAL A  72
THR A  80
VAL A  10
LEU A  84
LEU A  43
 None
 1.26A 4yb6A-3p0wA:
undetectable
4yb6E-3p0wA:
undetectable		 4yb6A-3p0wA:
22.13
4yb6E-3p0wA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_B_HISB302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		5 / 10 VAL A  72
THR A  80
VAL A  10
LEU A  84
LEU A  43
 None
 1.27A 4yb6B-3p0wA:
undetectable
4yb6C-3p0wA:
undetectable		 4yb6B-3p0wA:
22.13
4yb6C-3p0wA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_F_HISF302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		5 / 10 LEU A  84
LEU A  43
VAL A  72
THR A  80
VAL A  10
 None
 1.25A 4yb6B-3p0wA:
undetectable
4yb6F-3p0wA:
undetectable		 4yb6B-3p0wA:
22.13
4yb6F-3p0wA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		4 / 7 ALA A  90
ARG A  62
GLY A  60
GLU A  59
 None
 0.80A 5bs8A-3p0wA:
undetectable
5bs8C-3p0wA:
undetectable
5bs8D-3p0wA:
undetectable		 5bs8A-3p0wA:
23.40
5bs8C-3p0wA:
23.40
5bs8D-3p0wA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_E_GFNE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		4 / 7 ALA A  90
ARG A  62
GLY A  60
GLU A  59
 None
 0.79A 5btdA-3p0wA:
undetectable
5btdB-3p0wA:
undetectable
5btdC-3p0wA:
undetectable		 5btdA-3p0wA:
23.40
5btdB-3p0wA:
21.96
5btdC-3p0wA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		4 / 7 ALA A  90
ARG A  62
GLY A  60
GLU A  59
 None
 0.80A 5btdA-3p0wA:
undetectable
5btdC-3p0wA:
undetectable
5btdD-3p0wA:
undetectable		 5btdA-3p0wA:
23.40
5btdC-3p0wA:
23.40
5btdD-3p0wA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		4 / 6 ALA A  90
ARG A  62
GLY A  60
GLU A  59
 None
 0.79A 5btgA-3p0wA:
undetectable
5btgB-3p0wA:
undetectable
5btgC-3p0wA:
undetectable		 5btgA-3p0wA:
23.40
5btgB-3p0wA:
21.96
5btgC-3p0wA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		4 / 7 ALA A  90
ARG A  62
GLY A  60
GLU A  59
 None
 0.77A 5btgA-3p0wA:
undetectable
5btgC-3p0wA:
undetectable
5btgD-3p0wA:
undetectable		 5btgA-3p0wA:
23.40
5btgC-3p0wA:
23.40
5btgD-3p0wA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_E_MFXE2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		4 / 5 SER A 363
ARG A  62
GLY A  58
GLU A  59
 None
 1.01A 5cdqA-3p0wA:
undetectable
5cdqB-3p0wA:
undetectable
5cdqC-3p0wA:
undetectable		 5cdqA-3p0wA:
23.96
5cdqB-3p0wA:
20.55
5cdqC-3p0wA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_V_MFXV2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		4 / 5 SER A 363
ARG A  62
GLY A  58
GLU A  59
 None
 1.01A 5cdqR-3p0wA:
undetectable
5cdqS-3p0wA:
undetectable
5cdqT-3p0wA:
undetectable		 5cdqR-3p0wA:
23.96
5cdqS-3p0wA:
20.55
5cdqT-3p0wA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		5 / 12 ILE A 239
ALA A 237
LEU A 250
LYS A 221
ILE A 204
 None
None
None
GKR  A 472 (-3.0A)
None
 1.01A 5e8qA-3p0wA:
undetectable		 5e8qA-3p0wA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_A_SALA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		4 / 8 VAL A 148
LEU A 152
LEU A  84
ALA A 134
 None
 0.77A 5f1aA-3p0wA:
undetectable		 5f1aA-3p0wA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FXT_A_0LAA1376_1
(DNA POLYMERASE III
SUBUNIT BETA)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		4 / 7 LEU A 399
THR A 368
PRO A 409
MET A 335
 None
 1.04A 5fxtA-3p0wA:
undetectable		 5fxtA-3p0wA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		3 / 3 TRP A 256
GLU A 232
ASP A 251
 None
None
MG  A 471 ( 2.6A)
 0.57A 5gqbA-3p0wA:
5.2		 5gqbA-3p0wA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_1
(CYTOCHROME P450 2C9)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		5 / 12 ASN A  39
LEU A  65
GLY A  53
ALA A 134
LEU A  84
 None
 1.24A 5x23A-3p0wA:
undetectable		 5x23A-3p0wA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1431_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		4 / 7 HIS A  32
ASP A 251
GLY A 224
ASN A  27
 GKR  A 472 (-3.9A)
MG  A 471 ( 2.6A)
None
GKR  A 472 (-3.5A)
 1.12A 5x7pA-3p0wA:
undetectable		 5x7pA-3p0wA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1431_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		4 / 5 HIS A  32
ASP A 251
GLY A 224
ASN A  27
 GKR  A 472 (-3.9A)
MG  A 471 ( 2.6A)
None
GKR  A 472 (-3.5A)
 1.11A 5x7pB-3p0wA:
undetectable		 5x7pB-3p0wA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_2
(TUBULIN BETA CHAIN)		 3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN
(Ralstonia
pickettii) 		4 / 5 LEU A 394
THR A  37
PRO A 179
ARG A 173
 None
 1.11A 6ew0F-3p0wA:
2.3		 6ew0F-3p0wA:
11.72