SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3p11'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 3p11 RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3
(Homo
sapiens) 		5 / 12 VAL A 392
ILE A 380
ILE A 346
ASN A 350
LEU A 365
 None
 1.28A 1fm4A-3p11A:
undetectable		 1fm4A-3p11A:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BLA_A_CP6A302_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3p11 RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3
(Homo
sapiens) 		5 / 11 ILE A 374
ASP A 343
ILE A 435
ILE A 399
THR A 315
 None
 1.18A 2blaA-3p11A:
undetectable		 2blaA-3p11A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7F_A_NIOA601_1
(NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE)		 3p11 RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3
(Homo
sapiens) 		4 / 6 SER A 410
GLY A 376
THR A 375
ARG A 402
 None
 1.02A 2f7fA-3p11A:
undetectable		 2f7fA-3p11A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA801_1
(TRANSPORTER)		 3p11 RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3
(Homo
sapiens) 		5 / 11 LEU A  30
VAL A  40
ILE A  46
PHE A  57
LEU A  78
 None
 1.06A 2q6hA-3p11A:
undetectable		 2q6hA-3p11A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 3p11 RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3
(Homo
sapiens) 		5 / 12 LEU A  30
VAL A  40
ILE A  46
PHE A  57
LEU A  78
 None
 1.05A 2qb4A-3p11A:
undetectable		 2qb4A-3p11A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAT_A_CLMA301_0
(XENOBIOTIC
ACETYLTRANSFERASE)		 3p11 RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3
(Homo
sapiens) 		3 / 3 GLY A 376
TYR A 377
SER A 403
 None
 0.58A 2xatA-3p11A:
undetectable		 2xatA-3p11A:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3p11 RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3
(Homo
sapiens) 		5 / 12 ILE A 399
PHE A 424
ILE A 435
ILE A 437
LEU A 443
 None
 0.99A 3w67B-3p11A:
undetectable		 3w67B-3p11A:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3p11 RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3
(Homo
sapiens) 		5 / 12 LEU A 117
ILE A  46
VAL A  68
LEU A  44
VAL A  40
 None
 0.96A 3w68A-3p11A:
undetectable		 3w68A-3p11A:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3p11 RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3
(Homo
sapiens) 		5 / 12 VAL A 392
ILE A 380
ILE A 346
ASN A 350
LEU A 365
 None
 1.25A 4a84A-3p11A:
undetectable		 4a84A-3p11A:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_A_CAMA424_0
(CYTOCHROME P450)		 3p11 RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3
(Homo
sapiens) 		5 / 9 THR A  13
THR A  49
LEU A  33
LEU A  30
VAL A  19
 None
 1.41A 4c9kA-3p11A:
undetectable		 4c9kA-3p11A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_A_CAMA1419_0
(CYTOCHROME P450)		 3p11 RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3
(Homo
sapiens) 		5 / 8 TRP A 383
LEU A 360
LEU A 349
GLY A 348
THR A 323
 None
 1.35A 4c9nA-3p11A:
undetectable		 4c9nA-3p11A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JQ1_B_NPSB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3p11 RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3
(Homo
sapiens) 		4 / 8 VAL A 128
TRP A 144
ILE A 147
LEU A 117
 None
 0.93A 4jq1B-3p11A:
undetectable		 4jq1B-3p11A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3p11 RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3
(Homo
sapiens) 		4 / 6 ARG A 162
ASP A 159
VAL A  70
ALA A  71
 None
 0.91A 4nkxA-3p11A:
undetectable		 4nkxA-3p11A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 2)		 3p11 RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3
(Homo
sapiens) 		3 / 3 PHE A  75
THR A  13
LEU A  58
 None
 0.70A 4qztA-3p11A:
undetectable		 4qztA-3p11A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3p11 RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3
(Homo
sapiens) 		5 / 12 LEU A 463
LEU A 449
LYS A 453
LEU A 455
THR A 398
 None
 1.24A 4x1kA-3p11A:
undetectable
4x1kB-3p11A:
undetectable		 4x1kA-3p11A:
20.22
4x1kB-3p11A:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_B_ASDB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3p11 RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3
(Homo
sapiens) 		4 / 7 VAL A 128
TRP A 144
ILE A 147
LEU A  78
 None
 1.05A 4xo7B-3p11A:
undetectable		 4xo7B-3p11A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_B_ASDB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3p11 RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3
(Homo
sapiens) 		4 / 7 VAL A 128
TRP A 144
ILE A 147
LEU A  80
 None
 1.12A 4xo7B-3p11A:
undetectable		 4xo7B-3p11A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0S_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3p11 RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3
(Homo
sapiens) 		5 / 12 LEU A  58
LEU A  80
ILE A  61
VAL A  68
VAL A  70
 None
 0.95A 4y0sA-3p11A:
undetectable		 4y0sA-3p11A:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 3p11 RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3
(Homo
sapiens) 		4 / 8 GLU A  63
GLY A 265
GLY A 264
VAL A  39
 None
 0.75A 5f8yA-3p11A:
undetectable		 5f8yA-3p11A:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 3p11 RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3
(Homo
sapiens) 		4 / 8 GLU A  63
GLY A 265
GLY A 264
VAL A  39
 None
 0.78A 5f8yB-3p11A:
undetectable		 5f8yB-3p11A:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA810_0
(GEPHYRIN)		 3p11 RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3
(Homo
sapiens) 		3 / 3 LEU A 396
SER A 394
PHE A 393
 None
 0.61A 6fgcA-3p11A:
undetectable		 6fgcA-3p11A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA810_0
(GEPHYRIN)		 3p11 RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3
(Homo
sapiens) 		3 / 3 LEU A 412
SER A 410
PHE A 409
 None
 0.51A 6fgcA-3p11A:
undetectable		 6fgcA-3p11A:
21.16