SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3p19'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UAY_A_ADNA1001_1
(TYPE II
3-HYDROXYACYL-COA
DEHYDROGENASE)		 3p19 PUTATIVE BLUE
FLUORESCENT PROTEIN
(Vibrio
vulnificus) 		6 / 11 GLY A   9
SER A  12
ASP A  53
VAL A  54
ALA A  81
VAL A 103
 NDP  A2001 ( 3.3A)
NDP  A2001 ( 2.7A)
NDP  A2001 ( 3.5A)
NDP  A2001 ( 3.6A)
NDP  A2001 ( 3.6A)
NDP  A2001 ( 4.3A)
 0.43A 1uayA-3p19A:
28.8		 1uayA-3p19A:
29.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UAY_B_ADNB1002_1
(TYPE II
3-HYDROXYACYL-COA
DEHYDROGENASE)		 3p19 PUTATIVE BLUE
FLUORESCENT PROTEIN
(Vibrio
vulnificus) 		6 / 10 GLY A   9
SER A  12
ASP A  53
VAL A  54
ALA A  81
VAL A 103
 NDP  A2001 ( 3.3A)
NDP  A2001 ( 2.7A)
NDP  A2001 ( 3.5A)
NDP  A2001 ( 3.6A)
NDP  A2001 ( 3.6A)
NDP  A2001 ( 4.3A)
 0.45A 1uayB-3p19A:
29.2		 1uayB-3p19A:
29.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_E_SAME301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3p19 PUTATIVE BLUE
FLUORESCENT PROTEIN
(Vibrio
vulnificus) 		5 / 12 GLY A   9
ARG A  34
ASP A  53
ASN A  80
ALA A  81
 NDP  A2001 ( 3.3A)
NDP  A2001 ( 3.6A)
NDP  A2001 ( 3.5A)
NDP  A2001 ( 3.3A)
NDP  A2001 ( 3.6A)
 1.01A 2bm9E-3p19A:
5.7		 2bm9E-3p19A:
22.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JAP_A_J01A1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 3p19 PUTATIVE BLUE
FLUORESCENT PROTEIN
(Vibrio
vulnificus) 		7 / 12 MET A  84
LEU A  86
SER A 132
ALA A 134
TYR A 145
LEU A 182
TYR A 195
 None
None
NDP  A2001 ( 3.5A)
None
NDP  A2001 ( 4.7A)
NDP  A2001 ( 3.5A)
None
 0.46A 2japA-3p19A:
37.2		 2japA-3p19A:
39.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JAP_A_J01A1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 3p19 PUTATIVE BLUE
FLUORESCENT PROTEIN
(Vibrio
vulnificus) 		6 / 12 SER A 132
ILE A 133
ALA A 134
TYR A 145
LEU A 182
TYR A 195
 NDP  A2001 ( 3.5A)
None
None
NDP  A2001 ( 4.7A)
NDP  A2001 ( 3.5A)
None
 0.74A 2japA-3p19A:
37.2		 2japA-3p19A:
39.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JAP_B_J01B1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 3p19 PUTATIVE BLUE
FLUORESCENT PROTEIN
(Vibrio
vulnificus) 		7 / 12 MET A  84
LEU A  86
SER A 132
ALA A 134
TYR A 145
LEU A 182
TYR A 195
 None
None
NDP  A2001 ( 3.5A)
None
NDP  A2001 ( 4.7A)
NDP  A2001 ( 3.5A)
None
 0.46A 2japB-3p19A:
37.2		 2japB-3p19A:
39.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JAP_B_J01B1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 3p19 PUTATIVE BLUE
FLUORESCENT PROTEIN
(Vibrio
vulnificus) 		6 / 12 SER A 132
ILE A 133
ALA A 134
TYR A 145
LEU A 182
TYR A 195
 NDP  A2001 ( 3.5A)
None
None
NDP  A2001 ( 4.7A)
NDP  A2001 ( 3.5A)
None
 0.74A 2japB-3p19A:
37.2		 2japB-3p19A:
39.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JAP_C_J01C1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 3p19 PUTATIVE BLUE
FLUORESCENT PROTEIN
(Vibrio
vulnificus) 		7 / 12 MET A  84
LEU A  86
SER A 132
ALA A 134
TYR A 145
LEU A 182
TYR A 195
 None
None
NDP  A2001 ( 3.5A)
None
NDP  A2001 ( 4.7A)
NDP  A2001 ( 3.5A)
None
 0.48A 2japC-3p19A:
22.2		 2japC-3p19A:
39.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JAP_C_J01C1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 3p19 PUTATIVE BLUE
FLUORESCENT PROTEIN
(Vibrio
vulnificus) 		6 / 12 SER A 132
ILE A 133
ALA A 134
TYR A 145
LEU A 182
TYR A 195
 NDP  A2001 ( 3.5A)
None
None
NDP  A2001 ( 4.7A)
NDP  A2001 ( 3.5A)
None
 0.75A 2japC-3p19A:
22.2		 2japC-3p19A:
39.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JAP_D_J01D1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 3p19 PUTATIVE BLUE
FLUORESCENT PROTEIN
(Vibrio
vulnificus) 		7 / 12 MET A  84
LEU A  86
SER A 132
ALA A 134
TYR A 145
LEU A 182
TYR A 195
 None
None
NDP  A2001 ( 3.5A)
None
NDP  A2001 ( 4.7A)
NDP  A2001 ( 3.5A)
None
 0.47A 2japD-3p19A:
37.1		 2japD-3p19A:
39.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JAP_D_J01D1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 3p19 PUTATIVE BLUE
FLUORESCENT PROTEIN
(Vibrio
vulnificus) 		6 / 12 SER A 132
ILE A 133
ALA A 134
TYR A 145
LEU A 182
TYR A 195
 NDP  A2001 ( 3.5A)
None
None
NDP  A2001 ( 4.7A)
NDP  A2001 ( 3.5A)
None
 0.76A 2japD-3p19A:
37.1		 2japD-3p19A:
39.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_B_THHB643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3p19 PUTATIVE BLUE
FLUORESCENT PROTEIN
(Vibrio
vulnificus) 		5 / 12 VAL A 215
GLY A  15
SER A  12
ARG A  38
ILE A  14
 None
None
NDP  A2001 ( 2.7A)
None
NDP  A2001 ( 4.0A)
 1.21A 3k13B-3p19A:
undetectable		 3k13B-3p19A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3p19 PUTATIVE BLUE
FLUORESCENT PROTEIN
(Vibrio
vulnificus) 		5 / 12 VAL A 215
GLY A  15
SER A  12
ARG A  38
ILE A  14
 None
None
NDP  A2001 ( 2.7A)
None
NDP  A2001 ( 4.0A)
 1.20A 3k13C-3p19A:
2.4		 3k13C-3p19A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP5_B_KANB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3p19 PUTATIVE BLUE
FLUORESCENT PROTEIN
(Vibrio
vulnificus) 		3 / 3 ALA A  50
ARG A  66
LYS A  69
 None
 1.04A 3kp5B-3p19A:
undetectable		 3kp5B-3p19A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_B_RBFB190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 3p19 PUTATIVE BLUE
FLUORESCENT PROTEIN
(Vibrio
vulnificus) 		5 / 12 LEU A  32
THR A   8
ASN A 129
GLY A 111
ALA A  74
 None
 1.08A 3p5nB-3p19A:
undetectable		 3p5nB-3p19A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UZZ_A_TESA501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 3p19 PUTATIVE BLUE
FLUORESCENT PROTEIN
(Vibrio
vulnificus) 		4 / 7 TYR A 145
TYR A 195
MET A 202
TRP A 198
 NDP  A2001 ( 4.7A)
None
None
None
 1.37A 3uzzA-3p19A:
1.9		 3uzzA-3p19A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UZZ_B_ASDB501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 3p19 PUTATIVE BLUE
FLUORESCENT PROTEIN
(Vibrio
vulnificus) 		4 / 8 TYR A 145
TYR A 195
MET A 202
TRP A 198
 NDP  A2001 ( 4.7A)
None
None
None
 1.34A 3uzzB-3p19A:
undetectable		 3uzzB-3p19A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_B_SAMB1548_0
(CYSTATHIONINE
BETA-SYNTHASE)		 3p19 PUTATIVE BLUE
FLUORESCENT PROTEIN
(Vibrio
vulnificus) 		5 / 11 SER A  11
LEU A  32
GLN A  51
ALA A  50
VAL A  36
 NDP  A2001 ( 2.7A)
None
None
None
None
 1.29A 4uuuB-3p19A:
undetectable		 4uuuB-3p19A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UY8_7_TRP71002_0
(TRYPTOPHANASE)		 3p19 PUTATIVE BLUE
FLUORESCENT PROTEIN
(Vibrio
vulnificus) 		4 / 4 ILE A   7
ASN A  80
ILE A 173
VAL A 215
 None
NDP  A2001 ( 3.3A)
None
None
 1.03A 4uy87-3p19A:
undetectable		 4uy87-3p19A:
4.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HJI_A_ADNA401_1
(TRNA
(GUANINE(37)-N1)-MET
HYLTRANSFERASE TRM5A)		 3p19 PUTATIVE BLUE
FLUORESCENT PROTEIN
(Vibrio
vulnificus) 		5 / 11 GLY A  72
GLU A  68
ILE A  64
ASP A  61
PRO A 118
 None
 1.26A 5hjiA-3p19A:
5.8		 5hjiA-3p19A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_2
(CDL2.3A)		 3p19 PUTATIVE BLUE
FLUORESCENT PROTEIN
(Vibrio
vulnificus) 		4 / 8 ILE A 130
PRO A 175
ILE A 227
LEU A 108
 NDP  A2001 ( 4.6A)
NDP  A2001 ( 4.0A)
None
None
 0.94A 5ieoA-3p19A:
undetectable		 5ieoA-3p19A:
25.50