SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3p1i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3p1i EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		5 / 11 THR A  45
PHE A  96
LEU A 132
PHE A 181
VAL A 107
 None
 1.20A 1q23J-3p1iA:
undetectable		 1q23J-3p1iA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_2
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 3p1i EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		3 / 3 SER A 146
SER A 145
HIS A  57
 None
 0.60A 3mzeA-3p1iA:
undetectable		 3mzeA-3p1iA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_B_CLMB221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3p1i EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		5 / 12 THR A  45
LEU A 132
VAL A 157
PHE A 181
VAL A 107
 None
 1.38A 3u9fB-3p1iA:
undetectable
3u9fC-3p1iA:
undetectable		 3u9fB-3p1iA:
17.94
3u9fC-3p1iA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_H_CLMH221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3p1i EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		5 / 12 THR A  45
LEU A 132
VAL A 157
PHE A 181
VAL A 107
 None
 1.43A 3u9fH-3p1iA:
undetectable
3u9fI-3p1iA:
undetectable		 3u9fH-3p1iA:
17.94
3u9fI-3p1iA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3p1i EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		5 / 10 THR A  45
LEU A 132
VAL A 157
PHE A 181
VAL A 107
 None
 1.49A 3u9fI-3p1iA:
undetectable		 3u9fI-3p1iA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_J_CLMJ221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3p1i EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		5 / 12 THR A  45
LEU A 132
VAL A 157
PHE A 181
VAL A 107
 None
 1.42A 3u9fJ-3p1iA:
undetectable
3u9fK-3p1iA:
undetectable		 3u9fJ-3p1iA:
17.94
3u9fK-3p1iA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3p1i EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		5 / 10 THR A  45
LEU A 132
VAL A 157
PHE A 181
VAL A 107
 None
 1.46A 3u9fK-3p1iA:
undetectable		 3u9fK-3p1iA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_N_CLMN221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3p1i EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		5 / 11 THR A  45
LEU A 132
VAL A 157
PHE A 181
VAL A 107
 None
 1.45A 3u9fN-3p1iA:
undetectable
3u9fO-3p1iA:
undetectable		 3u9fN-3p1iA:
17.94
3u9fO-3p1iA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_P_CLMP221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3p1i EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		5 / 9 THR A  45
LEU A 132
VAL A 157
PHE A 181
VAL A 107
 None
 1.41A 3u9fP-3p1iA:
undetectable		 3u9fP-3p1iA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_S_CLMS221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3p1i EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		5 / 12 THR A  45
LEU A 132
VAL A 157
PHE A 181
VAL A 107
 None
 1.44A 3u9fP-3p1iA:
undetectable
3u9fS-3p1iA:
undetectable		 3u9fP-3p1iA:
17.94
3u9fS-3p1iA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_G_FK5G201_1
(FK506-BINDING
PROTEIN 1)		 3p1i EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		3 / 3 ILE A 119
PRO A 120
ILE A 122
 None
 0.42A 5hw8F-3p1iA:
undetectable		 5hw8F-3p1iA:
18.18