SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3p1u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ISM_B_NCAB305_0
(BONE MARROW STROMAL
CELL ANTIGEN 1)		 3p1u SUSD HOMOLOG
(Parabacteroides
distasonis) 		4 / 7 TRP A 541
LEU A 164
SER A 163
ASP A 166
 None
 1.26A 1ismB-3p1uA:
undetectable		 1ismB-3p1uA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRG_A_ADNA300_1
(ALPHA-MOMORCHARIN)		 3p1u SUSD HOMOLOG
(Parabacteroides
distasonis) 		5 / 9 ILE A 230
GLY A 393
TYR A 390
ILE A 395
ALA A 233
 None
 1.01A 1mrgA-3p1uA:
undetectable		 1mrgA-3p1uA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3p1u SUSD HOMOLOG
(Parabacteroides
distasonis) 		4 / 5 GLY A  51
ILE A  55
TRP A 132
VAL A 136
 None
 1.20A 1rs7A-3p1uA:
undetectable		 1rs7A-3p1uA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDT_A_VIAA1000_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3p1u SUSD HOMOLOG
(Parabacteroides
distasonis) 		5 / 12 ALA A 233
ILE A 230
ALA A 387
LEU A 449
PHE A 394
 None
 1.29A 1udtA-3p1uA:
undetectable		 1udtA-3p1uA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_B_URFB999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 3p1u SUSD HOMOLOG
(Parabacteroides
distasonis) 		4 / 7 ALA A 241
ILE A 179
ILE A 131
PHE A 209
 None
 0.79A 1upfB-3p1uA:
undetectable		 1upfB-3p1uA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VIF_A_FOLA1_0
(DIHYDROFOLATE
REDUCTASE)		 3p1u SUSD HOMOLOG
(Parabacteroides
distasonis) 		3 / 3 GLN A  67
ILE A  68
TYR A  71
 None
 0.74A 1vifA-3p1uA:
undetectable		 1vifA-3p1uA:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_D_CHDD702_0
(FERROCHELATASE)		 3p1u SUSD HOMOLOG
(Parabacteroides
distasonis) 		3 / 3 ARG A 473
GLY A 145
PRO A 146
 None
 0.42A 2hreD-3p1uA:
undetectable		 2hreD-3p1uA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_2
(PHOSPHOLIPASE A2)		 3p1u SUSD HOMOLOG
(Parabacteroides
distasonis) 		4 / 8 ASN A 290
LYS A 316
PRO A 319
PHE A 411
 None
 1.33A 3bjwD-3p1uA:
undetectable		 3bjwD-3p1uA:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_A_DVAA6_0
(GRAMICIDIN D)		 3p1u SUSD HOMOLOG
(Parabacteroides
distasonis) 		3 / 3 ALA A 308
VAL A 300
TRP A 296
 None
 0.84A 3l8lA-3p1uA:
undetectable
3l8lB-3p1uA:
undetectable		 3l8lA-3p1uA:
3.35
3l8lB-3p1uA:
3.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_0
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 3p1u SUSD HOMOLOG
(Parabacteroides
distasonis) 		5 / 12 ALA A 233
ILE A 237
LEU A 389
LEU A 221
LYS A 228
 None
 1.37A 3lcvB-3p1uA:
undetectable		 3lcvB-3p1uA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_F_SAMF228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 3p1u SUSD HOMOLOG
(Parabacteroides
distasonis) 		5 / 12 GLY A 406
ALA A 405
PHE A 411
ALA A 459
GLN A 455
 None
 1.23A 3nmuA-3p1uA:
undetectable
3nmuF-3p1uA:
undetectable		 3nmuA-3p1uA:
21.01
3nmuF-3p1uA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_F_SAMF228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 3p1u SUSD HOMOLOG
(Parabacteroides
distasonis) 		5 / 12 TYR A 423
ALA A 405
PHE A 411
ALA A 459
GLN A 455
 None
 1.25A 3nmuA-3p1uA:
undetectable
3nmuF-3p1uA:
undetectable		 3nmuA-3p1uA:
21.01
3nmuF-3p1uA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVK_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 3p1u SUSD HOMOLOG
(Parabacteroides
distasonis) 		5 / 12 GLU A 404
GLY A 406
PHE A 411
ALA A 459
GLN A 455
 None
 0.97A 3nvkF-3p1uA:
1.6
3nvkJ-3p1uA:
undetectable		 3nvkF-3p1uA:
20.40
3nvkJ-3p1uA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVK_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 3p1u SUSD HOMOLOG
(Parabacteroides
distasonis) 		5 / 12 GLU A 404
TYR A 423
PHE A 411
ALA A 459
GLN A 455
 None
 1.08A 3nvkF-3p1uA:
1.6
3nvkJ-3p1uA:
undetectable		 3nvkF-3p1uA:
20.40
3nvkJ-3p1uA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_1
(HIV-1 PROTEASE)		 3p1u SUSD HOMOLOG
(Parabacteroides
distasonis) 		4 / 7 GLY A 460
ALA A 459
VAL A 407
ILE A 453
 None
 0.68A 3t3cA-3p1uA:
undetectable		 3t3cA-3p1uA:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3p1u SUSD HOMOLOG
(Parabacteroides
distasonis) 		3 / 3 HIS A 383
GLU A 380
ASN A 250
 None
 0.98A 4bupB-3p1uA:
undetectable		 4bupB-3p1uA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_ACTA860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3p1u SUSD HOMOLOG
(Parabacteroides
distasonis) 		4 / 5 GLY A  51
ILE A  55
TRP A 132
VAL A 136
 None
 1.22A 4d33A-3p1uA:
undetectable		 4d33A-3p1uA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3p1u SUSD HOMOLOG
(Parabacteroides
distasonis) 		4 / 5 GLY A  51
ILE A  55
TRP A 132
VAL A 136
 None
 1.21A 4d33B-3p1uA:
undetectable		 4d33B-3p1uA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_F_ASWF101_1
(DNA TOPOISOMERASE
2-BETA)		 3p1u SUSD HOMOLOG
(Parabacteroides
distasonis) 		4 / 6 PRO A 314
GLY A 336
ALA A 321
GLN A 355
 None
 1.06A 4g0uA-3p1uA:
undetectable		 4g0uA-3p1uA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LA0_A_198A601_1
(SERUM ALBUMIN)		 3p1u SUSD HOMOLOG
(Parabacteroides
distasonis) 		5 / 10 ARG A 408
ALA A 459
PHE A 384
GLU A 402
LEU A 424
 None
 1.30A 4la0A-3p1uA:
undetectable		 4la0A-3p1uA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3p1u SUSD HOMOLOG
(Parabacteroides
distasonis) 		4 / 7 ASN A 518
GLU A 521
GLU A 523
GLU A 514
 None
 1.34A 4mj8C-3p1uA:
undetectable		 4mj8C-3p1uA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 3p1u SUSD HOMOLOG
(Parabacteroides
distasonis) 		5 / 9 ILE A 230
GLY A 393
TYR A 390
ILE A 395
ALA A 233
 None
 0.98A 4yp2B-3p1uA:
undetectable		 4yp2B-3p1uA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C6P_A_4YHA601_1
(PROTEIN C)		 3p1u SUSD HOMOLOG
(Parabacteroides
distasonis) 		4 / 6 ALA A 436
SER A 410
ASP A 318
PRO A 319
 None
 1.07A 5c6pA-3p1uA:
undetectable		 5c6pA-3p1uA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 3p1u SUSD HOMOLOG
(Parabacteroides
distasonis) 		5 / 9 ILE A 230
GLY A 393
TYR A 390
ILE A 395
ALA A 233
 None
 0.96A 5cf9B-3p1uA:
undetectable		 5cf9B-3p1uA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_A_SAMA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 3p1u SUSD HOMOLOG
(Parabacteroides
distasonis) 		3 / 3 HIS A 383
GLU A 380
ASN A 250
 None
 0.99A 5wbvA-3p1uA:
undetectable		 5wbvA-3p1uA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 3p1u SUSD HOMOLOG
(Parabacteroides
distasonis) 		3 / 3 HIS A 383
GLU A 380
ASN A 250
 None
 0.99A 5wbvB-3p1uA:
undetectable		 5wbvB-3p1uA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A4I_A_TRPA403_0
(TRYPTOPHAN
2,3-DIOXYGENASE)		 3p1u SUSD HOMOLOG
(Parabacteroides
distasonis) 		4 / 8 GLU A  60
ARG A 372
ILE A 278
PRO A  65
 None
 1.14A 6a4iA-3p1uA:
2.2		 6a4iA-3p1uA:
21.23