SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3p24'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 3p24 BFT-3
(Bacteroides
fragilis) 		4 / 6 ASN A 357
HIS A 348
ALA A 356
GLY A 355
 None
ZN  A 999 (-3.2A)
None
None
 1.00A 1c8lA-3p24A:
undetectable		 1c8lA-3p24A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_B_IPBB600_0
(ODORANT-BINDING
PROTEIN)		 3p24 BFT-3
(Bacteroides
fragilis) 		4 / 4 ILE A 353
MET A 346
VAL A 263
GLY A 334
 None
 1.36A 1e06B-3p24A:
3.1		 1e06B-3p24A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQG_A_IBPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3p24 BFT-3
(Bacteroides
fragilis) 		5 / 9 VAL A 248
VAL A 220
LEU A 260
ILE A 353
LEU A 389
 None
 1.01A 1eqgA-3p24A:
undetectable		 1eqgA-3p24A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQG_B_IBPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3p24 BFT-3
(Bacteroides
fragilis) 		5 / 11 VAL A 248
VAL A 220
LEU A 260
ILE A 353
LEU A 389
 None
 1.03A 1eqgB-3p24A:
undetectable		 1eqgB-3p24A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_A_FLPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3p24 BFT-3
(Bacteroides
fragilis) 		5 / 12 VAL A 248
VAL A 220
LEU A 260
ILE A 353
LEU A 389
 None
 1.00A 1eqhA-3p24A:
undetectable		 1eqhA-3p24A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_B_FLPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3p24 BFT-3
(Bacteroides
fragilis) 		5 / 12 VAL A 248
VAL A 220
LEU A 260
ILE A 353
LEU A 389
 None
 1.04A 1eqhB-3p24A:
undetectable		 1eqhB-3p24A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 3p24 BFT-3
(Bacteroides
fragilis) 		4 / 6 ASN A 357
HIS A 348
ALA A 356
GLY A 355
 None
ZN  A 999 (-3.2A)
None
None
 0.99A 1gfzA-3p24A:
undetectable		 1gfzA-3p24A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3p24 BFT-3
(Bacteroides
fragilis) 		4 / 8 GLY A 351
HIS A 348
ILE A 353
SER A 336
 None
ZN  A 999 (-3.2A)
None
None
 0.82A 1gtnP-3p24A:
undetectable
1gtnQ-3p24A:
undetectable		 1gtnP-3p24A:
15.07
1gtnQ-3p24A:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3003_1
(SERUM ALBUMIN)		 3p24 BFT-3
(Bacteroides
fragilis) 		3 / 4 LYS A 181
ALA A 180
MET A 341
 None
 0.92A 1hk3A-3p24A:
undetectable		 1hk3A-3p24A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3p24 BFT-3
(Bacteroides
fragilis) 		4 / 6 ASN A 357
HIS A 348
ALA A 356
GLY A 355
 None
ZN  A 999 (-3.2A)
None
None
 0.97A 1l5qA-3p24A:
undetectable		 1l5qA-3p24A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3p24 BFT-3
(Bacteroides
fragilis) 		4 / 6 ASN A 357
HIS A 348
ALA A 356
GLY A 355
 None
ZN  A 999 (-3.2A)
None
None
 0.98A 1l5qB-3p24A:
undetectable		 1l5qB-3p24A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5R_A_RBFA859_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3p24 BFT-3
(Bacteroides
fragilis) 		5 / 11 ASN A 357
HIS A 348
TYR A 191
ALA A 356
GLY A 355
 None
ZN  A 999 (-3.2A)
ZN  A 999 ( 4.6A)
None
None
 1.34A 1l5rA-3p24A:
undetectable		 1l5rA-3p24A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3p24 BFT-3
(Bacteroides
fragilis) 		4 / 6 ASN A 357
HIS A 348
ALA A 356
GLY A 355
 None
ZN  A 999 (-3.2A)
None
None
 1.01A 1l7xA-3p24A:
undetectable		 1l7xA-3p24A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3p24 BFT-3
(Bacteroides
fragilis) 		4 / 6 ASN A 357
HIS A 348
ALA A 356
GLY A 355
 None
ZN  A 999 (-3.2A)
None
None
 0.97A 1l7xB-3p24A:
undetectable		 1l7xB-3p24A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)		 3p24 BFT-3
(Bacteroides
fragilis) 		4 / 5 HIS A 348
GLU A 349
HIS A 352
HIS A 358
 ZN  A 999 (-3.2A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.2A)
ZN  A 999 ( 3.2A)
 0.23A 1os2A-3p24A:
8.7		 1os2A-3p24A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)		 3p24 BFT-3
(Bacteroides
fragilis) 		4 / 4 HIS A 348
GLU A 349
HIS A 352
HIS A 358
 ZN  A 999 (-3.2A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.2A)
ZN  A 999 ( 3.2A)
 0.20A 1os2D-3p24A:
8.7		 1os2D-3p24A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)		 3p24 BFT-3
(Bacteroides
fragilis) 		4 / 4 HIS A 348
GLU A 349
HIS A 352
HIS A 358
 ZN  A 999 (-3.2A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.2A)
ZN  A 999 ( 3.2A)
 0.10A 1uttA-3p24A:
8.9		 1uttA-3p24A:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)		 3p24 BFT-3
(Bacteroides
fragilis) 		4 / 4 HIS A 348
GLU A 349
HIS A 352
HIS A 358
 ZN  A 999 (-3.2A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.2A)
ZN  A 999 ( 3.2A)
 0.16A 1utzA-3p24A:
8.9		 1utzA-3p24A:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)		 3p24 BFT-3
(Bacteroides
fragilis) 		4 / 4 HIS A 348
GLU A 349
HIS A 352
HIS A 358
 ZN  A 999 (-3.2A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.2A)
ZN  A 999 ( 3.2A)
 0.14A 1utzB-3p24A:
8.9		 1utzB-3p24A:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y93_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 3p24 BFT-3
(Bacteroides
fragilis) 		5 / 6 ILE A 313
HIS A 348
GLU A 349
HIS A 352
HIS A 358
 None
ZN  A 999 (-3.2A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.2A)
ZN  A 999 ( 3.2A)
 0.55A 1y93A-3p24A:
8.9		 1y93A-3p24A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3p24 BFT-3
(Bacteroides
fragilis) 		3 / 3 HIS A 358
HIS A 352
HIS A 348
 ZN  A 999 ( 3.2A)
ZN  A 999 (-3.2A)
ZN  A 999 (-3.2A)
 0.73A 2einN-3p24A:
undetectable		 2einN-3p24A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 3p24 BFT-3
(Bacteroides
fragilis) 		4 / 4 HIS A 348
GLU A 349
HIS A 352
HIS A 358
 ZN  A 999 (-3.2A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.2A)
ZN  A 999 ( 3.2A)
 0.14A 2hu6A-3p24A:
8.8		 2hu6A-3p24A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_A_097A1001_1
(ADAMTS-1)		 3p24 BFT-3
(Bacteroides
fragilis) 		5 / 9 LEU A 314
HIS A 348
GLU A 349
HIS A 352
HIS A 358
 None
ZN  A 999 (-3.2A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.2A)
ZN  A 999 ( 3.2A)
 0.43A 2jihA-3p24A:
15.0		 2jihA-3p24A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_B_097B1001_1
(ADAMTS-1)		 3p24 BFT-3
(Bacteroides
fragilis) 		5 / 8 LEU A 314
HIS A 348
GLU A 349
HIS A 352
HIS A 358
 None
ZN  A 999 (-3.2A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.2A)
ZN  A 999 ( 3.2A)
 0.28A 2jihB-3p24A:
15.5		 2jihB-3p24A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		 3p24 BFT-3
(Bacteroides
fragilis) 		5 / 12 ILE A 353
VAL A 220
LEU A 260
PHE A 262
PHE A 302
 None
 1.42A 2jj8C-3p24A:
undetectable		 2jj8C-3p24A:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUB_A_2TNA134_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3p24 BFT-3
(Bacteroides
fragilis) 		4 / 4 LEU A 319
ILE A 384
HIS A 358
LYS A 197
 None
None
ZN  A 999 ( 3.2A)
None
 1.33A 2oubA-3p24A:
0.0		 2oubA-3p24A:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 3p24 BFT-3
(Bacteroides
fragilis) 		4 / 6 HIS A 348
GLU A 349
HIS A 352
HIS A 358
 ZN  A 999 (-3.2A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.2A)
ZN  A 999 ( 3.2A)
 0.23A 2ow9A-3p24A:
8.6		 2ow9A-3p24A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_B_HAEB502_1
(COLLAGENASE 3)		 3p24 BFT-3
(Bacteroides
fragilis) 		4 / 4 HIS A 348
GLU A 349
HIS A 352
HIS A 358
 ZN  A 999 (-3.2A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.2A)
ZN  A 999 ( 3.2A)
 0.18A 2ow9B-3p24A:
8.5		 2ow9B-3p24A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)		 3p24 BFT-3
(Bacteroides
fragilis) 		4 / 4 HIS A 348
GLU A 349
HIS A 352
HIS A 358
 ZN  A 999 (-3.2A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.2A)
ZN  A 999 ( 3.2A)
 0.22A 2ozrC-3p24A:
8.5		 2ozrC-3p24A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_D_HAED3002_1
(COLLAGENASE 3)		 3p24 BFT-3
(Bacteroides
fragilis) 		4 / 4 HIS A 348
GLU A 349
HIS A 352
HIS A 358
 ZN  A 999 (-3.2A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.2A)
ZN  A 999 ( 3.2A)
 0.27A 2ozrD-3p24A:
8.5		 2ozrD-3p24A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)		 3p24 BFT-3
(Bacteroides
fragilis) 		4 / 4 HIS A 348
GLU A 349
HIS A 352
HIS A 358
 ZN  A 999 (-3.2A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.2A)
ZN  A 999 ( 3.2A)
 0.27A 2ozrE-3p24A:
8.7		 2ozrE-3p24A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_F_HAEF3004_1
(COLLAGENASE 3)		 3p24 BFT-3
(Bacteroides
fragilis) 		3 / 3 HIS A 348
HIS A 352
HIS A 358
 ZN  A 999 (-3.2A)
ZN  A 999 (-3.2A)
ZN  A 999 ( 3.2A)
 0.26A 2ozrF-3p24A:
8.6		 2ozrF-3p24A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEO_A_LNRA200_1
(D7R4 PROTEIN)		 3p24 BFT-3
(Bacteroides
fragilis) 		5 / 12 GLU A  88
ILE A  83
VAL A  90
PHE A 109
MET A 131
 None
 1.36A 2qeoA-3p24A:
undetectable		 2qeoA-3p24A:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVD_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3p24 BFT-3
(Bacteroides
fragilis) 		3 / 3 HIS A 358
HIS A 352
HIS A 348
 ZN  A 999 ( 3.2A)
ZN  A 999 (-3.2A)
ZN  A 999 (-3.2A)
 0.76A 3bvdA-3p24A:
undetectable		 3bvdA-3p24A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKZ_A_ZMRA469_2
(NEURAMINIDASE)		 3p24 BFT-3
(Bacteroides
fragilis) 		4 / 6 ASP A  66
ARG A 116
ILE A 158
SER A 161
 None
 1.45A 3ckzA-3p24A:
undetectable		 3ckzA-3p24A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3p24 BFT-3
(Bacteroides
fragilis) 		4 / 6 ASN A 357
HIS A 348
ALA A 356
GLY A 355
 None
ZN  A 999 (-3.2A)
None
None
 0.97A 3dd1A-3p24A:
undetectable		 3dd1A-3p24A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3p24 BFT-3
(Bacteroides
fragilis) 		4 / 6 ASN A 357
HIS A 348
ALA A 356
GLY A 355
 None
ZN  A 999 (-3.2A)
None
None
 0.97A 3dd1B-3p24A:
undetectable		 3dd1B-3p24A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3p24 BFT-3
(Bacteroides
fragilis) 		4 / 6 ASN A 357
HIS A 348
ALA A 356
GLY A 355
 None
ZN  A 999 (-3.2A)
None
None
 0.98A 3ddsA-3p24A:
undetectable		 3ddsA-3p24A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3p24 BFT-3
(Bacteroides
fragilis) 		4 / 6 ASN A 357
HIS A 348
ALA A 356
GLY A 355
 None
ZN  A 999 (-3.2A)
None
None
 0.98A 3ddsB-3p24A:
undetectable		 3ddsB-3p24A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3p24 BFT-3
(Bacteroides
fragilis) 		4 / 6 ASN A 357
HIS A 348
ALA A 356
GLY A 355
 None
ZN  A 999 (-3.2A)
None
None
 0.98A 3ddwA-3p24A:
undetectable		 3ddwA-3p24A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3p24 BFT-3
(Bacteroides
fragilis) 		4 / 6 ASN A 357
HIS A 348
ALA A 356
GLY A 355
 None
ZN  A 999 (-3.2A)
None
None
 0.97A 3ddwB-3p24A:
undetectable		 3ddwB-3p24A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_B_097B801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 3p24 BFT-3
(Bacteroides
fragilis) 		5 / 9 LEU A 314
HIS A 348
GLU A 349
HIS A 352
HIS A 358
 None
ZN  A 999 (-3.2A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.2A)
ZN  A 999 ( 3.2A)
 0.41A 3hy7B-3p24A:
15.1		 3hy7B-3p24A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 3p24 BFT-3
(Bacteroides
fragilis) 		4 / 5 HIS A 348
GLU A 349
HIS A 352
HIS A 358
 ZN  A 999 (-3.2A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.2A)
ZN  A 999 ( 3.2A)
 0.16A 3kecA-3p24A:
8.6		 3kecA-3p24A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_B_HAEB271_1
(COLLAGENASE 3)		 3p24 BFT-3
(Bacteroides
fragilis) 		3 / 3 HIS A 348
GLU A 349
HIS A 352
 ZN  A 999 (-3.2A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.2A)
 0.14A 3kecB-3p24A:
8.5		 3kecB-3p24A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 3p24 BFT-3
(Bacteroides
fragilis) 		4 / 5 HIS A 348
GLU A 349
HIS A 352
HIS A 358
 ZN  A 999 (-3.2A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.2A)
ZN  A 999 ( 3.2A)
 0.17A 3likA-3p24A:
8.8		 3likA-3p24A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 3p24 BFT-3
(Bacteroides
fragilis) 		4 / 4 HIS A 348
GLU A 349
HIS A 352
HIS A 358
 ZN  A 999 (-3.2A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.2A)
ZN  A 999 ( 3.2A)
 0.14A 3lilA-3p24A:
8.8		 3lilA-3p24A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LJG_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 3p24 BFT-3
(Bacteroides
fragilis) 		5 / 5 ILE A 313
HIS A 348
GLU A 349
HIS A 352
HIS A 358
 None
ZN  A 999 (-3.2A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.2A)
ZN  A 999 ( 3.2A)
 0.38A 3ljgA-3p24A:
8.9		 3ljgA-3p24A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 3p24 BFT-3
(Bacteroides
fragilis) 		4 / 5 HIS A 348
GLU A 349
HIS A 352
HIS A 358
 ZN  A 999 (-3.2A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.2A)
ZN  A 999 ( 3.2A)
 0.18A 3lkaA-3p24A:
8.8		 3lkaA-3p24A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_2
(HIV-1 PROTEASE)		 3p24 BFT-3
(Bacteroides
fragilis) 		6 / 11 ALA A 332
VAL A 222
GLY A 351
ILE A 385
VAL A 220
ILE A 300
 None
 1.48A 3lzvB-3p24A:
undetectable		 3lzvB-3p24A:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_1
(PROTEASE)		 3p24 BFT-3
(Bacteroides
fragilis) 		6 / 10 ALA A 332
VAL A 222
GLY A 351
ILE A 385
VAL A 220
ILE A 300
 None
 1.48A 3nujA-3p24A:
undetectable		 3nujA-3p24A:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_1
(HIV-1 PROTEASE)		 3p24 BFT-3
(Bacteroides
fragilis) 		6 / 11 ALA A 332
VAL A 222
GLY A 351
ILE A 385
VAL A 220
ILE A 300
 None
 1.46A 3oy4A-3p24A:
undetectable		 3oy4A-3p24A:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S38_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3p24 BFT-3
(Bacteroides
fragilis) 		3 / 3 HIS A 358
HIS A 352
HIS A 348
 ZN  A 999 ( 3.2A)
ZN  A 999 (-3.2A)
ZN  A 999 (-3.2A)
 0.78A 3s38A-3p24A:
undetectable		 3s38A-3p24A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 3p24 BFT-3
(Bacteroides
fragilis) 		4 / 6 HIS A 348
GLU A 349
HIS A 352
HIS A 358
 ZN  A 999 (-3.2A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.2A)
ZN  A 999 ( 3.2A)
 0.28A 4a7bA-3p24A:
8.5		 4a7bA-3p24A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_2
(CYTOCHROME P450
21-HYDROXYLASE)		 3p24 BFT-3
(Bacteroides
fragilis) 		3 / 3 LEU A 186
VAL A 177
ASP A 178
 None
None
GOL  A 505 ( 3.6A)
 0.62A 4y8wC-3p24A:
undetectable		 4y8wC-3p24A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_0
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 3p24 BFT-3
(Bacteroides
fragilis) 		5 / 12 GLY A 351
SER A 247
TYR A 195
ALA A 356
ASN A 357
 None
 1.18A 4ymgB-3p24A:
undetectable		 4ymgB-3p24A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 3p24 BFT-3
(Bacteroides
fragilis) 		4 / 4 HIS A 348
GLU A 349
HIS A 352
HIS A 358
 ZN  A 999 (-3.2A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.2A)
ZN  A 999 ( 3.2A)
 0.15A 5n5jA-3p24A:
8.8		 5n5jA-3p24A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 3p24 BFT-3
(Bacteroides
fragilis) 		5 / 5 ILE A 313
HIS A 348
GLU A 349
HIS A 352
HIS A 358
 None
ZN  A 999 (-3.2A)
ZN  A 999 ( 4.9A)
ZN  A 999 (-3.2A)
ZN  A 999 ( 3.2A)
 0.54A 5n5kA-3p24A:
8.7		 5n5kA-3p24A:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_B_C2FB702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3p24 BFT-3
(Bacteroides
fragilis) 		5 / 12 ASN A 275
GLY A 274
ASP A 277
GLY A 315
ILE A 316
 None
 1.11A 5vooB-3p24A:
undetectable		 5vooB-3p24A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_D_C2FD3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3p24 BFT-3
(Bacteroides
fragilis) 		5 / 12 ASN A 275
GLY A 274
ASP A 277
GLY A 315
ILE A 316
 None
 1.06A 5vooD-3p24A:
undetectable		 5vooD-3p24A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_F_C2FF3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3p24 BFT-3
(Bacteroides
fragilis) 		5 / 12 ASN A 275
GLY A 274
ASP A 277
GLY A 315
ILE A 316
 None
 1.05A 5vooF-3p24A:
undetectable		 5vooF-3p24A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3p24 BFT-3
(Bacteroides
fragilis) 		5 / 12 ASN A 275
GLY A 274
ASP A 277
GLY A 315
ILE A 316
 None
 1.07A 5vopB-3p24A:
undetectable		 5vopB-3p24A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3p24 BFT-3
(Bacteroides
fragilis) 		3 / 3 HIS A 358
HIS A 352
HIS A 348
 ZN  A 999 ( 3.2A)
ZN  A 999 (-3.2A)
ZN  A 999 (-3.2A)
 0.69A 5x1fN-3p24A:
undetectable		 5x1fN-3p24A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_1
(CYTOCHROME P450 1A1)		 3p24 BFT-3
(Bacteroides
fragilis) 		4 / 5 ILE A 304
SER A 336
ALA A 239
LEU A  85
 None
 0.97A 6dwnA-3p24A:
undetectable		 6dwnA-3p24A:
9.05