SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3p28'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6F_C_010C6_0
(INFECTIOUS
BRONCHITIS VIRUS
(IBV) MAIN PROTEASE
N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE)		 3p28 GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		3 / 3 ASN A 122
LEU A  93
HIS A 121
 None
 0.80A 2q6fB-3p28A:
undetectable		 2q6fB-3p28A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_F_CSCF1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 3p28 GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		5 / 12 THR A  11
LYS A  83
PHE A 219
ASP A  55
PHE A  52
 None
 1.29A 2vavF-3p28A:
0.0		 2vavF-3p28A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EIG_A_MTXA200_2
(DIHYDROFOLATE
REDUCTASE)		 3p28 GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		4 / 5 ASP A 132
ARG A 120
ILE A 119
VAL A 102
 None
 1.07A 3eigA-3p28A:
undetectable		 3eigA-3p28A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3p28 GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		4 / 5 VAL A 102
THR A 138
GLY A 112
LYS A 110
 None
 1.14A 3elzB-3p28A:
0.9		 3elzB-3p28A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGY_A_GLYA510_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3p28 GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		4 / 6 ILE A 140
PHE A  35
ALA A  39
ASN A 137
 None
 1.14A 3pgyA-3p28A:
undetectable
3pgyB-3p28A:
undetectable		 3pgyA-3p28A:
19.71
3pgyB-3p28A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 3p28 GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		5 / 9 PHE A  23
VAL A  64
ASN A  73
ILE A 206
PHE A 200
 None
GYS  A  18 ( 4.7A)
GYS  A  18 ( 3.6A)
None
None
 1.21A 3t3rB-3p28A:
undetectable		 3t3rB-3p28A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_C_9PLC501_1
(CYTOCHROME P450 2A6)		 3p28 GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		5 / 9 PHE A  23
VAL A  64
ASN A  73
ILE A 206
PHE A 200
 None
GYS  A  18 ( 4.7A)
GYS  A  18 ( 3.6A)
None
None
 1.25A 3t3rC-3p28A:
undetectable		 3t3rC-3p28A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 3p28 GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		5 / 10 PHE A  23
VAL A  64
ASN A  73
ILE A 206
PHE A 200
 None
GYS  A  18 ( 4.7A)
GYS  A  18 ( 3.6A)
None
None
 1.20A 3t3rD-3p28A:
undetectable		 3t3rD-3p28A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE504_0
(RNA POLYMERASE
3D-POL)		 3p28 GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		3 / 3 VAL A 214
GLY A 216
LYS A 218
 None
 0.76A 4k50E-3p28A:
undetectable		 4k50E-3p28A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3p28 GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		5 / 10 SER A  38
LEU A 153
SER A  24
ILE A 104
PRO A 148
 None
 1.47A 6dlzB-3p28A:
undetectable
6dlzC-3p28A:
undetectable		 6dlzB-3p28A:
15.64
6dlzC-3p28A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3p28 GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		5 / 10 SER A  38
LEU A 153
SER A  24
ILE A 104
PRO A 148
 None
 1.47A 6dm1B-3p28A:
undetectable
6dm1C-3p28A:
undetectable		 6dm1B-3p28A:
15.64
6dm1C-3p28A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3p28 GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		5 / 10 SER A  38
LEU A 153
SER A  24
ILE A 104
PRO A 148
 None
 1.46A 6dm2B-3p28A:
undetectable
6dm2C-3p28A:
undetectable		 6dm2B-3p28A:
15.64
6dm2C-3p28A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3p28 GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		5 / 10 ILE A 104
PRO A 148
SER A  38
LEU A 153
SER A  24
 None
 1.47A 6dm2A-3p28A:
undetectable
6dm2D-3p28A:
undetectable		 6dm2A-3p28A:
15.64
6dm2D-3p28A:
15.64