SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3p2a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MZ9_A_VDYA1002_4 (CARTILAGE OLIGOMERIC MATRIX PROTEIN)	3p2a	PUTATIVE THIOREDOXIN-LIKE PROTEIN (Yersinia pestis)	4 / 5	LEU A 14 CYH A 5 ALA A 7 CYH A 8	None ZN A 151 (-2.3A) ZN A 151 ( 4.9A) ZN A 151 (-2.3A)	1.16A	1mz9D-3p2aA: undetectable	1mz9D-3p2aA: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZZB_A_ACTA404_0 (PROTON-GATED ION CHANNEL)	3p2a	PUTATIVE THIOREDOXIN-LIKE PROTEIN (Yersinia pestis)	4 / 4	LEU A 49 ILE A 57 ARG A 101 TYR A 113	None	1.43A	4zzbA-3p2aA: 0.0	4zzbA-3p2aA: 19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZZC_A_ACTA406_0 (PROTON-GATED ION CHANNEL)	3p2a	PUTATIVE THIOREDOXIN-LIKE PROTEIN (Yersinia pestis)	4 / 4	LEU A 49 ILE A 57 ARG A 101 TYR A 113	None	1.37A	4zzcA-3p2aA: undetectable	4zzcA-3p2aA: 19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZZC_B_ACTB406_0 (PROTON-GATED ION CHANNEL)	3p2a	PUTATIVE THIOREDOXIN-LIKE PROTEIN (Yersinia pestis)	4 / 4	LEU A 49 ILE A 57 ARG A 101 TYR A 113	None	1.39A	4zzcB-3p2aA: undetectable	4zzcB-3p2aA: 19.30

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1MZ9_A_VDYA1002_4","CARTILAGE OLIGOMERIC MATRIX PROTEIN;CARTILAGE OLIGOMERIC MATRIX PROTEIN","3p2a","PUTATIVE THIOREDOXIN-LIKE PROTEIN","Yersinia pestis",4,"LEU A  14;CYH A   5;ALA A   7;CYH A   8","None; ZN A 151 (-2.3A); ZN A 151 ( 4.9A); ZN A 151 (-2.3A)","1.16A","1mz9D-3p2aA:undetectable","1mz9D-3p2aA:16.67"],["4ZZB_A_ACTA404_0","PROTON-GATED ION CHANNEL","3p2a","PUTATIVE THIOREDOXIN-LIKE PROTEIN","Yersinia pestis",4,"LEU A  49;ILE A  57;ARG A 101;TYR A 113","None","1.43A","4zzbA-3p2aA:0.0","4zzbA-3p2aA:19.30"],["4ZZC_A_ACTA406_0","PROTON-GATED ION CHANNEL","3p2a","PUTATIVE THIOREDOXIN-LIKE PROTEIN","Yersinia pestis",4,"LEU A  49;ILE A  57;ARG A 101;TYR A 113","None","1.37A","4zzcA-3p2aA:undetectable","4zzcA-3p2aA:19.30"],["4ZZC_B_ACTB406_0","PROTON-GATED ION CHANNEL","3p2a","PUTATIVE THIOREDOXIN-LIKE PROTEIN","Yersinia pestis",4,"LEU A  49;ILE A  57;ARG A 101;TYR A 113","None","1.39A","4zzcB-3p2aA:undetectable","4zzcB-3p2aA:19.30"]]