SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3p2c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMC_B_SAMB105_0
(MET REPRESSOR)		 3p2c PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
ovatus) 		5 / 10 GLU A 340
ARG A 269
LEU A 277
LEU A 349
ALA A 338
 None
 1.32A 1cmcA-3p2cA:
undetectable
1cmcB-3p2cA:
undetectable		 1cmcA-3p2cA:
15.22
1cmcB-3p2cA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 3p2c PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
ovatus) 		4 / 8 TYR A 374
THR A 419
VAL A 381
VAL A 355
 None
 1.16A 1dz9A-3p2cA:
undetectable		 1dz9A-3p2cA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_1
(HYPOTHETICAL PROTEIN
RV2118C)		 3p2c PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
ovatus) 		3 / 3 GLU A 340
HIS A 348
ASP A 273
 None
 0.74A 1i9gA-3p2cA:
undetectable		 1i9gA-3p2cA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M4I_A_KANA500_1
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 3p2c PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
ovatus) 		4 / 8 ASP A 352
GLY A 397
SER A 446
THR A 456
 None
 0.90A 1m4iA-3p2cA:
undetectable		 1m4iA-3p2cA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_B_SAMB1293_1
(GLYCINE
N-METHYLTRANSFERASE)		 3p2c PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
ovatus) 		4 / 5 ARG A 194
MET A 411
ASN A 386
TYR A 191
 None
 1.48A 1nbiB-3p2cA:
0.0		 1nbiB-3p2cA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_A_CAMA1416_0
(CYTOCHROME P450-CAM)		 3p2c PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
ovatus) 		4 / 8 TYR A 374
THR A 419
VAL A 381
VAL A 355
 None
 1.10A 1uyuA-3p2cA:
undetectable		 1uyuA-3p2cA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 3p2c PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
ovatus) 		4 / 8 TYR A 374
THR A 419
VAL A 381
VAL A 355
 None
 1.16A 1uyuB-3p2cA:
undetectable		 1uyuB-3p2cA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 3p2c PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
ovatus) 		3 / 3 HIS A  91
ASP A 116
ASN A 156
 None
 0.78A 1wg8B-3p2cA:
undetectable		 1wg8B-3p2cA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3p2c PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
ovatus) 		4 / 5 LEU A 263
ALA A 287
ILE A 186
SER A 283
 None
 1.01A 2othA-3p2cA:
undetectable		 2othA-3p2cA:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_1
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 3p2c PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
ovatus) 		3 / 3 GLN A 145
THR A 106
TRP A 462
 None
 1.11A 2rctA-3p2cA:
undetectable		 2rctA-3p2cA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSC_B_PQNB1773_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3p2c PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
ovatus) 		5 / 10 SER A 308
ARG A 292
ALA A 315
LEU A 291
ALA A 294
 None
 1.42A 2wscB-3p2cA:
0.3		 2wscB-3p2cA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSE_B_PQNB1774_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3p2c PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
ovatus) 		5 / 10 SER A 308
ARG A 292
ALA A 315
LEU A 291
ALA A 294
 None
 1.41A 2wseB-3p2cA:
0.5		 2wseB-3p2cA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSF_B_PQNB1773_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3p2c PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
ovatus) 		5 / 9 SER A 308
ARG A 292
ALA A 315
LEU A 291
ALA A 294
 None
 1.43A 2wsfB-3p2cA:
0.3		 2wsfB-3p2cA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_A_X2NA1480_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3p2c PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
ovatus) 		5 / 12 MET A 414
PHE A 418
TYR A 363
PRO A 410
MET A 443
 None
 1.14A 2x2nA-3p2cA:
undetectable		 2x2nA-3p2cA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_A_X2NA1480_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3p2c PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
ovatus) 		5 / 12 MET A 414
PHE A 418
TYR A 363
PRO A 410
THR A  85
 None
 1.32A 2x2nA-3p2cA:
undetectable		 2x2nA-3p2cA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_B_X2NB1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3p2c PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
ovatus) 		5 / 12 MET A 414
PHE A 418
TYR A 363
PRO A 410
MET A 443
 None
 1.21A 2x2nB-3p2cA:
undetectable		 2x2nB-3p2cA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_4
(HIV-1 PROTEASE)		 3p2c PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
ovatus) 		4 / 4 LEU A 349
ASP A 352
VAL A 381
THR A 377
 None
 1.19A 3cyxB-3p2cA:
undetectable		 3cyxB-3p2cA:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3p2c PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
ovatus) 		5 / 10 SER A 308
ARG A 292
ALA A 315
LEU A 291
ALA A 294
 None
 1.42A 3lw5B-3p2cA:
undetectable		 3lw5B-3p2cA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3p2c PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
ovatus) 		4 / 8 PHE A 238
SER A 267
ARG A 240
VAL A 249
 None
 1.29A 3rqlA-3p2cA:
undetectable
3rqlB-3p2cA:
undetectable		 3rqlA-3p2cA:
22.03
3rqlB-3p2cA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_F_ACTF402_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 3p2c PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
ovatus) 		3 / 3 PHE A 158
ASP A 160
ARG A 144
 None
 0.87A 4eahF-3p2cA:
undetectable		 4eahF-3p2cA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_G_ACTG401_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 3p2c PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
ovatus) 		3 / 3 PHE A 158
ASP A 160
ARG A 144
 None
 0.87A 4eahG-3p2cA:
undetectable		 4eahG-3p2cA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IOM_A_FOLA608_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 3p2c PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
ovatus) 		4 / 7 ALA A 417
GLU A 477
LEU A 474
LEU A 470
 None
 1.03A 4iomA-3p2cA:
undetectable		 4iomA-3p2cA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3p2c PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
ovatus) 		4 / 8 TYR A 374
THR A 419
VAL A 381
VAL A 355
 None
 1.13A 4l4fA-3p2cA:
undetectable		 4l4fA-3p2cA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3p2c PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
ovatus) 		5 / 12 LEU A 127
VAL A  58
PHE A  78
LEU A 470
VAL A  65
 None
 1.20A 4nc3A-3p2cA:
undetectable		 4nc3A-3p2cA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RFQ_A_SAMA401_1
(HISTIDINE PROTEIN
METHYLTRANSFERASE 1
HOMOLOG)		 3p2c PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
ovatus) 		4 / 4 THR A 456
GLY A 399
ASP A 352
SER A 446
 None
 1.37A 4rfqA-3p2cA:
undetectable		 4rfqA-3p2cA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_B_ADNB301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 3p2c PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
ovatus) 		5 / 9 LEU A 195
GLY A 118
ILE A 208
LEU A 143
VAL A 141
 None
 1.16A 4x3mB-3p2cA:
undetectable		 4x3mB-3p2cA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3p2c PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
ovatus) 		4 / 7 PRO A 401
SER A 283
PHE A 339
ASP A 273
 None
 1.32A 5a1iA-3p2cA:
undetectable		 5a1iA-3p2cA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 3p2c PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
ovatus) 		3 / 3 GLU A 340
HIS A 348
ASP A 273
 None
 0.76A 5c0oG-3p2cA:
undetectable		 5c0oG-3p2cA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA617_0
(SERUM ALBUMIN)		 3p2c PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
ovatus) 		3 / 3 TRP A 462
ARG A 115
LEU A 364
 None
 0.98A 5dbyA-3p2cA:
undetectable		 5dbyA-3p2cA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		 3p2c PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
ovatus) 		4 / 7 SER A 271
PRO A 401
PHE A 339
SER A 266
 None
 1.24A 5l1fC-3p2cA:
undetectable		 5l1fC-3p2cA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8D_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 3p2c PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
ovatus) 		3 / 3 THR A  79
PRO A  83
ASP A  87
 None
 0.76A 5l8dB-3p2cA:
undetectable		 5l8dB-3p2cA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWU_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 3p2c PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
ovatus) 		3 / 3 THR A  79
PRO A  83
ASP A  87
 None
 0.76A 5mwuB-3p2cA:
undetectable		 5mwuB-3p2cA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCY_A_DB8A401_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 3p2c PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
ovatus) 		4 / 4 VAL A  90
LEU A 138
ASN A  84
ASP A  87
 None
 0.98A 5vcyA-3p2cA:
undetectable		 5vcyA-3p2cA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G6R_A_SAMA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3p2c PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
ovatus) 		4 / 7 PRO A 401
SER A 283
PHE A 339
ASP A 273
 None
 1.31A 6g6rA-3p2cA:
undetectable		 6g6rA-3p2cA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 3p2c PUTATIVE GLYCOSYL
HYDROLASE
(Bacteroides
ovatus) 		3 / 3 THR A  89
GLU A  59
ASN A  84
 None
 0.72A 6nj9K-3p2cA:
undetectable		 6nj9K-3p2cA:
20.97