SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3p2n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_A_RBFA98_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 3p2n 3,6-ANHYDRO-ALPHA-L-
GALACTOSIDASE
(Zobellia
galactanivorans) 		5 / 10 LEU A 373
LEU A 359
ILE A 311
THR A 333
ILE A 324
 None
 1.25A 1i18A-3p2nA:
undetectable
1i18B-3p2nA:
undetectable		 1i18A-3p2nA:
11.30
1i18B-3p2nA:
11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1U_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 3p2n 3,6-ANHYDRO-ALPHA-L-
GALACTOSIDASE
(Zobellia
galactanivorans) 		5 / 10 ILE A 255
VAL A 201
TYR A 186
LEU A 203
TYR A 296
 None
 1.41A 1s1uA-3p2nA:
undetectable		 1s1uA-3p2nA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN0_B_T44B602_1
(TRANSTHYRETIN)		 3p2n 3,6-ANHYDRO-ALPHA-L-
GALACTOSIDASE
(Zobellia
galactanivorans) 		4 / 7 GLU A 153
ALA A 156
LEU A 184
ALA A 206
 None
 1.10A 1sn0B-3p2nA:
undetectable
1sn0D-3p2nA:
undetectable		 1sn0B-3p2nA:
14.96
1sn0D-3p2nA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_B_SCKB951_1
(ACETYLCHOLINESTERASE)		 3p2n 3,6-ANHYDRO-ALPHA-L-
GALACTOSIDASE
(Zobellia
galactanivorans) 		4 / 8 TYR A 258
ASP A 339
TYR A 263
TYR A 301
 None
 1.39A 2ha2B-3p2nA:
undetectable		 2ha2B-3p2nA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YS6_A_GLYA431_0
(PHOSPHORIBOSYLGLYCIN
AMIDE SYNTHETASE)		 3p2n 3,6-ANHYDRO-ALPHA-L-
GALACTOSIDASE
(Zobellia
galactanivorans) 		4 / 8 ASP A 339
TYR A 258
GLY A 319
PRO A 338
 None
 0.91A 2ys6A-3p2nA:
undetectable		 2ys6A-3p2nA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM9_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3p2n 3,6-ANHYDRO-ALPHA-L-
GALACTOSIDASE
(Zobellia
galactanivorans) 		5 / 9 ALA A 337
ILE A 341
GLY A 340
ILE A 320
TYR A 263
 None
 1.48A 2zm9A-3p2nA:
undetectable		 2zm9A-3p2nA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGX_A_SALA102_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 3p2n 3,6-ANHYDRO-ALPHA-L-
GALACTOSIDASE
(Zobellia
galactanivorans) 		4 / 7 VAL A 286
ILE A 256
TYR A 263
ILE A 255
 None
 0.98A 3hgxA-3p2nA:
undetectable		 3hgxA-3p2nA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_B_XRAB233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3p2n 3,6-ANHYDRO-ALPHA-L-
GALACTOSIDASE
(Zobellia
galactanivorans) 		5 / 11 VAL A 352
GLY A 308
ASN A 306
GLU A 310
ILE A 311
 None
 1.38A 3owxA-3p2nA:
undetectable
3owxB-3p2nA:
undetectable		 3owxA-3p2nA:
20.05
3owxB-3p2nA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3p2n 3,6-ANHYDRO-ALPHA-L-
GALACTOSIDASE
(Zobellia
galactanivorans) 		4 / 5 ALA A 337
GLY A 319
ASP A 290
ASP A 339
 None
 1.00A 4n48A-3p2nA:
undetectable		 4n48A-3p2nA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11802_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
UL4
RIBOSOMAL PROTEIN
UL15
RIBOSOMAL PROTEIN
EL15)		 3p2n 3,6-ANHYDRO-ALPHA-L-
GALACTOSIDASE
(Zobellia
galactanivorans) 		3 / 3 ARG A 159
LYS A 215
ARG A 136
 None
 1.39A 6az3C-3p2nA:
undetectable
6az3L-3p2nA:
undetectable
6az3M-3p2nA:
undetectable		 6az3C-3p2nA:
10.80
6az3L-3p2nA:
10.88
6az3M-3p2nA:
11.39