SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3p2p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OXR_A_AINA141_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 3p2p PHOSPHOLIPASE A2
(Sus
scrofa) 		4 / 4 LEU A   2
GLY A  30
ASP A  49
TYR A  69
 None
CA  A 125 (-4.3A)
CA  A 125 (-2.1A)
None
 0.58A 1oxrA-3p2pA:
21.9		 1oxrA-3p2pA:
57.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TD7_A_NFLA2001_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 3p2p PHOSPHOLIPASE A2
(Sus
scrofa) 		5 / 9 LEU A   2
ILE A   9
PHE A  22
GLY A  30
PHE A 106
 None
None
None
CA  A 125 (-4.3A)
None
 0.44A 1td7A-3p2pA:
21.6		 1td7A-3p2pA:
57.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TD7_A_NFLA2001_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 3p2p PHOSPHOLIPASE A2
(Sus
scrofa) 		5 / 9 LEU A   2
ILE A   9
PHE A  22
TYR A  69
PHE A 106
 None
 0.79A 1td7A-3p2pA:
21.6		 1td7A-3p2pA:
57.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 3p2p PHOSPHOLIPASE A2
(Sus
scrofa) 		5 / 7 GLY A  30
HIS A  48
ASP A  49
TYR A  52
PRO A  68
 CA  A 125 (-4.3A)
None
CA  A 125 (-2.1A)
None
None
 0.54A 1th6A-3p2pA:
18.1		 1th6A-3p2pA:
41.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3p2p PHOSPHOLIPASE A2
(Sus
scrofa) 		5 / 7 GLY A  30
HIS A  48
ASP A  49
TYR A  52
PRO A  68
 CA  A 125 (-4.3A)
None
CA  A 125 (-2.1A)
None
None
 0.54A 2armA-3p2pA:
18.1		 2armA-3p2pA:
41.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AZY_A_CHDA237_0
(PHOSPHOLIPASE A2,
MAJOR ISOENZYME)		 3p2p PHOSPHOLIPASE A2
(Sus
scrofa) 		6 / 11 ILE A   9
ILE A  13
HIS A  17
GLY A  30
LEU A  41
PHE A 106
 None
None
None
CA  A 125 (-4.3A)
None
None
 0.83A 2azyA-3p2pA:
19.9		 2azyA-3p2pA:
93.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AZY_A_CHDA237_0
(PHOSPHOLIPASE A2,
MAJOR ISOENZYME)		 3p2p PHOSPHOLIPASE A2
(Sus
scrofa) 		7 / 11 ILE A   9
ILE A  13
TYR A  25
GLY A  30
LEU A  41
PHE A 106
TYR A 111
 None
None
None
CA  A 125 (-4.3A)
None
None
None
 0.38A 2azyA-3p2pA:
19.9		 2azyA-3p2pA:
93.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3p2p PHOSPHOLIPASE A2
(Sus
scrofa) 		4 / 6 LEU A   2
HIS A  48
ASP A  49
TYR A  52
 None
None
CA  A 125 (-2.1A)
None
 0.75A 2dpzA-3p2pA:
18.3		 2dpzA-3p2pA:
41.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FO7_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3p2p PHOSPHOLIPASE A2
(Sus
scrofa) 		4 / 5 HIS A  48
ASP A  49
TYR A  52
PRO A  68
 None
CA  A 125 (-2.1A)
None
None
 0.42A 3fo7A-3p2pA:
18.0		 3fo7A-3p2pA:
41.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H1X_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3p2p PHOSPHOLIPASE A2
(Sus
scrofa) 		4 / 5 HIS A  48
ASP A  49
TYR A  52
PRO A  68
 None
CA  A 125 (-2.1A)
None
None
 0.44A 3h1xA-3p2pA:
18.1		 3h1xA-3p2pA:
41.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OSH_A_OINA5811_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 3p2p PHOSPHOLIPASE A2
(Sus
scrofa) 		7 / 9 LEU A   2
PHE A   5
ILE A   9
PHE A  22
GLY A  30
HIS A  48
TYR A  69
 None
None
None
None
CA  A 125 (-4.3A)
None
None
 0.65A 3oshA-3p2pA:
21.7		 3oshA-3p2pA:
58.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 3p2p PHOSPHOLIPASE A2
(Sus
scrofa) 		4 / 5 TYR A  75
ILE A  82
LEU A   2
PHE A   5
 None
 0.93A 5kmdC-3p2pA:
undetectable
5kmdD-3p2pA:
undetectable		 5kmdC-3p2pA:
13.99
5kmdD-3p2pA:
13.99