SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3p2y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_A_CCSA47_0
(GLUTATHIONE
S-TRANSFERASE)		 3p2y ALANINE
DEHYDROGENASE/PYRIDI
NE NUCLEOTIDE
TRANSHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		4 / 7 LEU A 334
THR A   2
GLY A  31
LEU A  27
 None
 0.93A 1gtiA-3p2yA:
undetectable		 1gtiA-3p2yA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBN_A_CAMA442_0
(CYTOCHROME P450-CAM)		 3p2y ALANINE
DEHYDROGENASE/PYRIDI
NE NUCLEOTIDE
TRANSHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		4 / 7 THR A 327
VAL A  20
VAL A   6
VAL A  36
 None
 1.00A 2qbnA-3p2yA:
undetectable		 2qbnA-3p2yA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZG_B_NCAB302_0
(ADP-RIBOSYL CYCLASE
1)		 3p2y ALANINE
DEHYDROGENASE/PYRIDI
NE NUCLEOTIDE
TRANSHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		4 / 7 LEU A 308
GLU A 283
SER A 306
THR A 291
 None
 1.27A 3dzgB-3p2yA:
3.8		 3dzgB-3p2yA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3p2y ALANINE
DEHYDROGENASE/PYRIDI
NE NUCLEOTIDE
TRANSHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		4 / 7 GLU A  14
PHE A  90
HIS A 317
VAL A  23
 None
 0.99A 4a97D-3p2yA:
undetectable		 4a97D-3p2yA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_B_SAMB301_0
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 3p2y ALANINE
DEHYDROGENASE/PYRIDI
NE NUCLEOTIDE
TRANSHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLN A 131
GLY A  89
ASN A  71
ALA A 110
ALA A 112
 None
 1.39A 4pclB-3p2yA:
4.9		 4pclB-3p2yA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_F_SAMF501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3p2y ALANINE
DEHYDROGENASE/PYRIDI
NE NUCLEOTIDE
TRANSHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 LEU A  19
PRO A   7
GLY A  41
VAL A  70
ALA A 323
 None
 1.17A 5o96E-3p2yA:
3.6
5o96F-3p2yA:
2.7		 5o96E-3p2yA:
23.98
5o96F-3p2yA:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_A_SAMA501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 3p2y ALANINE
DEHYDROGENASE/PYRIDI
NE NUCLEOTIDE
TRANSHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLY A  84
ASP A 331
ASP A  65
LEU A  27
LEU A  32
 None
None
CA  A 361 ( 4.1A)
None
None
 1.14A 5wwsA-3p2yA:
4.8		 5wwsA-3p2yA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E5Z_A_CCSA106_0
(PROTEIN/NUCLEIC ACID
DEGLYCASE DJ-1)		 3p2y ALANINE
DEHYDROGENASE/PYRIDI
NE NUCLEOTIDE
TRANSHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 GLY A 285
GLY A 286
ASN A 287
ALA A 259
PRO A 258
 None
 1.04A 6e5zA-3p2yA:
4.1		 6e5zA-3p2yA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA820_0
(GEPHYRIN)		 3p2y ALANINE
DEHYDROGENASE/PYRIDI
NE NUCLEOTIDE
TRANSHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		4 / 5 GLU A 114
PRO A  93
THR A  95
GLN A  96
 None
 1.29A 6fgdA-3p2yA:
3.4		 6fgdA-3p2yA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NQA_K_SAMK500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 3p2y ALANINE
DEHYDROGENASE/PYRIDI
NE NUCLEOTIDE
TRANSHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 ASP A 193
GLY A 170
GLY A 172
GLN A 201
VAL A 198
 None
 1.33A 6nqaK-3p2yA:
4.4		 6nqaK-3p2yA:
20.18