SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3p39'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_A_HSMA401_1
(NITROPHORIN 1)		 3p39 NONSTRUCTURAL
PROTEIN 1
(Influenza
A
virus) 		4 / 4 ASP A 168
LEU A 158
LEU A 161
LEU A 110
 None
 1.35A 1u18A-3p39A:
undetectable		 1u18A-3p39A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2002_1
(SERUM ALBUMIN)		 3p39 NONSTRUCTURAL
PROTEIN 1
(Influenza
A
virus) 		5 / 10 ALA A 172
LEU A 125
LEU A 142
ALA A 144
LEU A 110
 None
 1.19A 2bxeA-3p39A:
undetectable		 2bxeA-3p39A:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_2
(PROTEASE)		 3p39 NONSTRUCTURAL
PROTEIN 1
(Influenza
A
virus) 		5 / 12 VAL A 189
GLY A 174
GLY A 153
GLY A 178
ILE A 177
 None
 0.88A 4q5mA-3p39A:
undetectable		 4q5mA-3p39A:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA602_1
(SERUM ALBUMIN)		 3p39 NONSTRUCTURAL
PROTEIN 1
(Influenza
A
virus) 		4 / 8 ASP A 168
ASN A 171
ALA A 172
VAL A 175
 None
 0.55A 4zbqA-3p39A:
undetectable		 4zbqA-3p39A:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_F_SAMF301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 3p39 NONSTRUCTURAL
PROTEIN 1
(Influenza
A
virus) 		5 / 12 GLY A 174
GLY A 178
GLY A 179
LEU A 180
LEU A 142
 None
 0.91A 5c0oF-3p39A:
undetectable		 5c0oF-3p39A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3p39 NONSTRUCTURAL
PROTEIN 1
(Influenza
A
virus) 		3 / 3 ARG A 135
ILE A 132
PHE A 133
 None
 0.58A 5kirA-3p39A:
undetectable		 5kirA-3p39A:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA307_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 3p39 NONSTRUCTURAL
PROTEIN 1
(Influenza
A
virus) 		4 / 5 ASP A  87
GLU A  91
ARG A 143
THR A  89
 None
 1.42A 5uxcA-3p39A:
undetectable		 5uxcA-3p39A:
20.40