SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3p3a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 3p3a THIOSULFATE
SULFURTRANSFERASE
(Mycolicibacteriu
m
thermoresistibil
e) 		3 / 3 TYR A  73
GLU A 250
THR A 276
 None
 0.92A 2y7hB-3p3aA:
undetectable		 2y7hB-3p3aA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_D_MIXD101_1
(DNA TOPOISOMERASE
2-BETA)		 3p3a THIOSULFATE
SULFURTRANSFERASE
(Mycolicibacteriu
m
thermoresistibil
e) 		4 / 6 ARG A 251
GLY A 249
ASN A  66
GLU A 250
 None
 1.09A 4g0vB-3p3aA:
undetectable		 4g0vB-3p3aA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_A_TKTA508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3p3a THIOSULFATE
SULFURTRANSFERASE
(Mycolicibacteriu
m
thermoresistibil
e) 		5 / 8 ASP A 156
ILE A 159
TRP A 256
ARG A 160
TYR A 107
 None
 1.36A 6hisA-3p3aA:
undetectable
6hisB-3p3aA:
undetectable		 6hisA-3p3aA:
14.75
6hisB-3p3aA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_B_TKTB508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3p3a THIOSULFATE
SULFURTRANSFERASE
(Mycolicibacteriu
m
thermoresistibil
e) 		5 / 8 ASP A 156
ILE A 159
TRP A 256
ARG A 160
TYR A 107
 None
 1.35A 6hisB-3p3aA:
undetectable
6hisC-3p3aA:
undetectable		 6hisB-3p3aA:
14.75
6hisC-3p3aA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_C_TKTC508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3p3a THIOSULFATE
SULFURTRANSFERASE
(Mycolicibacteriu
m
thermoresistibil
e) 		5 / 8 ASP A 156
ILE A 159
TRP A 256
ARG A 160
TYR A 107
 None
 1.35A 6hisC-3p3aA:
undetectable
6hisD-3p3aA:
undetectable		 6hisC-3p3aA:
14.75
6hisD-3p3aA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_D_TKTD501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3p3a THIOSULFATE
SULFURTRANSFERASE
(Mycolicibacteriu
m
thermoresistibil
e) 		5 / 8 ASP A 156
ILE A 159
TRP A 256
ARG A 160
TYR A 107
 None
 1.36A 6hisD-3p3aA:
undetectable
6hisE-3p3aA:
undetectable		 6hisD-3p3aA:
14.75
6hisE-3p3aA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_E_TKTE501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3p3a THIOSULFATE
SULFURTRANSFERASE
(Mycolicibacteriu
m
thermoresistibil
e) 		5 / 8 TYR A 107
ASP A 156
ILE A 159
TRP A 256
ARG A 160
 None
 1.35A 6hisA-3p3aA:
undetectable
6hisE-3p3aA:
undetectable		 6hisA-3p3aA:
14.75
6hisE-3p3aA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 3p3a THIOSULFATE
SULFURTRANSFERASE
(Mycolicibacteriu
m
thermoresistibil
e) 		5 / 9 ALA A 199
GLY A 198
GLY A 273
ASN A 280
ARG A 201
 None
 1.10A 6nm4B-3p3aA:
undetectable		 6nm4B-3p3aA:
20.81