SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3p3d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZE_A_RBFA98_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 3p3d NUCLEOPORIN 53
(Meyerozyma
guilliermondii) 		5 / 9 LEU A 292
ASP A 328
ILE A 268
LYS A 300
ILE A 282
 None
 1.27A 1hzeA-3p3dA:
undetectable
1hzeB-3p3dA:
undetectable		 1hzeA-3p3dA:
24.24
1hzeB-3p3dA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZE_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 3p3d NUCLEOPORIN 53
(Meyerozyma
guilliermondii) 		5 / 9 ILE A 282
LEU A 292
ASP A 328
ILE A 268
LYS A 300
 None
 1.27A 1hzeA-3p3dA:
undetectable
1hzeB-3p3dA:
undetectable		 1hzeA-3p3dA:
24.24
1hzeB-3p3dA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_0
(16S RRNA METHYLASE)		 3p3d NUCLEOPORIN 53
(Meyerozyma
guilliermondii) 		5 / 12 GLY A 350
GLY A 272
VAL A 347
ALA A 342
LEU A 269
 None
 1.04A 3p2kC-3p3dA:
undetectable		 3p2kC-3p3dA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 3p3d NUCLEOPORIN 53
(Meyerozyma
guilliermondii) 		4 / 8 VAL A 314
TYR A 327
THR A 326
ILE A 325
 None
 0.93A 5mzrE-3p3dA:
undetectable		 5mzrE-3p3dA:
20.45