SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3p3k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YGP_A_PCFA1213_0 (WNT INHIBITORY FACTOR 1)	3p3k	TRANSLATIONALLY-CONT ROLLED TUMOR PROTEIN HOMOLOG (Plasmodium falciparum)	5 / 12	ILE A 149 PHE A 124 PHE A 28 VAL A 40 PRO A 161	None	1.05A	2ygpA-3p3kA: undetectable	2ygpA-3p3kA: 19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HRD_B_NIOB5661_1 (NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT)	3p3k	TRANSLATIONALLY-CONT ROLLED TUMOR PROTEIN HOMOLOG (Plasmodium falciparum)	4 / 8	ILE A 125 ALA A 121 PHE A 117 ALA A 103	None	0.85A	3hrdA-3p3kA: undetectable 3hrdB-3p3kA: undetectable	3hrdA-3p3kA: 16.90 3hrdB-3p3kA: 18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IV0_B_SAMB302_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE, PUTATIVE)	3p3k	TRANSLATIONALLY-CONT ROLLED TUMOR PROTEIN HOMOLOG (Plasmodium falciparum)	5 / 12	ILE A 149 ILE A 75 ASP A 74 ILE A 73 SER A 152	None	1.10A	4iv0B-3p3kA: undetectable	4iv0B-3p3kA: 22.34

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2YGP_A_PCFA1213_0","WNT INHIBITORY FACTOR 1","3p3k","TRANSLATIONALLY-CONTROLLED TUMOR PROTEIN HOMOLOG","Plasmodium falciparum",5,"ILE A 149;PHE A 124;PHE A  28;VAL A  40;PRO A 161","None","1.05A","2ygpA-3p3kA:undetectable","2ygpA-3p3kA:19.50"],["3HRD_B_NIOB5661_1","NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT;NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT","3p3k","TRANSLATIONALLY-CONTROLLED TUMOR PROTEIN HOMOLOG","Plasmodium falciparum",4,"ILE A 125;ALA A 121;PHE A 117;ALA A 103","None","0.85A","3hrdA-3p3kA:undetectable;3hrdB-3p3kA:undetectable","3hrdA-3p3kA:16.90;3hrdB-3p3kA:18.52"],["4IV0_B_SAMB302_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE, PUTATIVE","3p3k","TRANSLATIONALLY-CONTROLLED TUMOR PROTEIN HOMOLOG","Plasmodium falciparum",5,"ILE A 149;ILE A  75;ASP A  74;ILE A  73;SER A 152","None","1.10A","4iv0B-3p3kA:undetectable","4iv0B-3p3kA:22.34"]]