SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3p3q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CD2_A_FOLA307_1
(DIHYDROFOLATE
REDUCTASE)		 3p3q MMOQ
(Methylococcus
capsulatus) 		3 / 3 GLU A 191
ILE A 188
ARG A 204
 None
 0.78A 1cd2A-3p3qA:
undetectable		 1cd2A-3p3qA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 3p3q MMOQ
(Methylococcus
capsulatus) 		4 / 7 THR A  68
LEU A  72
VAL A  86
ILE A  90
 None
 0.86A 1t87B-3p3qA:
undetectable		 1t87B-3p3qA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_D_ASDD1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3p3q MMOQ
(Methylococcus
capsulatus) 		5 / 9 LEU A 207
PRO A 213
ALA A  87
ALA A 153
PHE A 237
 None
 1.10A 2vcvD-3p3qA:
undetectable		 2vcvD-3p3qA:
25.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_E_ASDE1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3p3q MMOQ
(Methylococcus
capsulatus) 		5 / 9 LEU A 207
PRO A 213
ALA A  87
ALA A 153
PHE A 237
 None
 1.10A 2vcvE-3p3qA:
undetectable		 2vcvE-3p3qA:
25.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_G_ASDG1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3p3q MMOQ
(Methylococcus
capsulatus) 		4 / 7 LEU A 207
PRO A 213
ALA A  87
PHE A 237
 None
 0.91A 2vcvG-3p3qA:
undetectable		 2vcvG-3p3qA:
25.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_H_ASDH1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3p3q MMOQ
(Methylococcus
capsulatus) 		5 / 9 LEU A 207
PRO A 213
ALA A  87
ALA A 153
PHE A 237
 None
 1.16A 2vcvH-3p3qA:
undetectable		 2vcvH-3p3qA:
25.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_I_ASDI1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3p3q MMOQ
(Methylococcus
capsulatus) 		5 / 9 LEU A 207
PRO A 213
ALA A  87
ALA A 153
PHE A 237
 None
 1.06A 2vcvI-3p3qA:
undetectable		 2vcvI-3p3qA:
25.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A500_1
(ORF12)		 3p3q MMOQ
(Methylococcus
capsulatus) 		5 / 10 ILE A 141
LEU A 220
LEU A 138
GLY A 157
ALA A 160
 None
 1.20A 2xf3A-3p3qA:
undetectable		 2xf3A-3p3qA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_B_SFYB806_0
(SEPIAPTERIN
REDUCTASE)		 3p3q MMOQ
(Methylococcus
capsulatus) 		5 / 11 LEU A 165
SER A 131
LEU A 132
TYR A 127
ALA A  66
 None
 1.25A 4hwkB-3p3qA:
undetectable		 4hwkB-3p3qA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_C_SFYC804_0
(SEPIAPTERIN
REDUCTASE)		 3p3q MMOQ
(Methylococcus
capsulatus) 		5 / 12 LEU A 165
SER A 131
LEU A 132
TYR A 127
ALA A  66
 None
 1.26A 4hwkC-3p3qA:
undetectable		 4hwkC-3p3qA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_D_SFYD803_0
(SEPIAPTERIN
REDUCTASE)		 3p3q MMOQ
(Methylococcus
capsulatus) 		5 / 11 LEU A 165
SER A 131
LEU A 132
TYR A 127
ALA A  66
 None
 1.25A 4hwkD-3p3qA:
undetectable		 4hwkD-3p3qA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 3p3q MMOQ
(Methylococcus
capsulatus) 		5 / 12 GLN A 103
ALA A  47
VAL A  52
LEU A  98
GLU A  50
 SO4  A   1 (-3.5A)
None
None
None
None
 1.25A 4pd5A-3p3qA:
1.5		 4pd5A-3p3qA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 3p3q MMOQ
(Methylococcus
capsulatus) 		5 / 12 GLN A 103
ALA A  47
VAL A  52
LEU A  98
GLU A  50
 SO4  A   1 (-3.5A)
None
None
None
None
 1.26A 4pd9A-3p3qA:
1.4		 4pd9A-3p3qA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XR4_B_AG2B511_1
(HOMOSPERMIDINE
SYNTHASE)		 3p3q MMOQ
(Methylococcus
capsulatus) 		3 / 3 VAL A  89
PHE A 104
ARG A  70
 None
 0.68A 4xr4B-3p3qA:
undetectable		 4xr4B-3p3qA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3p3q MMOQ
(Methylococcus
capsulatus) 		5 / 12 ALA A  75
VAL A 101
ALA A 105
SER A 107
LEU A 108
 None
 1.10A 5kirB-3p3qA:
undetectable		 5kirB-3p3qA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 3p3q MMOQ
(Methylococcus
capsulatus) 		5 / 12 GLY A 157
LEU A 132
VAL A 136
ALA A 137
LEU A 138
 None
 0.74A 5kpcA-3p3qA:
undetectable		 5kpcA-3p3qA:
19.60