SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3p40'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 3p40 NEUROFASCIN
(Homo
sapiens) 		3 / 3 THR A 367
PRO A 366
THR A 410
 None
 0.87A 1a7yB-3p40A:
undetectable		 1a7yB-3p40A:
2.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 3p40 NEUROFASCIN
(Homo
sapiens) 		3 / 3 THR A 410
THR A 367
PRO A 366
 None
 0.81A 1a7yB-3p40A:
undetectable		 1a7yB-3p40A:
2.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 3p40 NEUROFASCIN
(Homo
sapiens) 		3 / 3 THR A 410
THR A 367
PRO A 366
 None
 0.87A 1fjaC-3p40A:
undetectable		 1fjaC-3p40A:
2.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 3p40 NEUROFASCIN
(Homo
sapiens) 		3 / 3 THR A 410
THR A 367
PRO A 366
 None
 0.87A 1fjaD-3p40A:
undetectable		 1fjaD-3p40A:
2.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 3p40 NEUROFASCIN
(Homo
sapiens) 		3 / 3 THR A 410
THR A 367
PRO A 366
 None
 0.83A 1i3wE-3p40A:
undetectable		 1i3wE-3p40A:
2.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 3p40 NEUROFASCIN
(Homo
sapiens) 		3 / 3 THR A 367
PRO A 366
THR A 410
 None
 0.83A 1i3wG-3p40A:
undetectable		 1i3wG-3p40A:
2.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 3p40 NEUROFASCIN
(Homo
sapiens) 		3 / 3 THR A 410
THR A 367
PRO A 366
 None
 0.84A 1i3wG-3p40A:
undetectable		 1i3wG-3p40A:
2.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 3p40 NEUROFASCIN
(Homo
sapiens) 		3 / 3 THR A 410
THR A 367
PRO A 366
 None
 0.85A 1i3wH-3p40A:
undetectable		 1i3wH-3p40A:
2.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)		 3p40 NEUROFASCIN
(Homo
sapiens) 		3 / 3 THR A 410
THR A 367
PRO A 366
 None
 0.84A 1qfiB-3p40A:
undetectable		 1qfiB-3p40A:
2.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 3p40 NEUROFASCIN
(Homo
sapiens) 		3 / 3 THR A 367
PRO A 366
THR A 410
 None
 0.82A 1unjF-3p40A:
undetectable		 1unjF-3p40A:
2.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 3p40 NEUROFASCIN
(Homo
sapiens) 		3 / 3 THR A 367
PRO A 366
THR A 410
 None
 0.84A 1unjL-3p40A:
undetectable		 1unjL-3p40A:
2.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 3p40 NEUROFASCIN
(Homo
sapiens) 		3 / 3 THR A 367
PRO A 366
THR A 410
 None
 0.82A 1unmE-3p40A:
undetectable		 1unmE-3p40A:
2.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 3p40 NEUROFASCIN
(Homo
sapiens) 		3 / 3 THR A 367
PRO A 366
THR A 410
 None
 0.87A 1unmF-3p40A:
undetectable		 1unmF-3p40A:
2.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 3p40 NEUROFASCIN
(Homo
sapiens) 		3 / 3 THR A 410
THR A 367
PRO A 366
 None
 0.73A 209dC-3p40A:
undetectable		 209dC-3p40A:
2.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_B_SAMB402_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 3p40 NEUROFASCIN
(Homo
sapiens) 		5 / 12 PHE A 219
LEU A 141
GLY A 167
PRO A 165
ILE A  52
 None
 1.17A 2zznB-3p40A:
undetectable		 2zznB-3p40A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)		 3p40 NEUROFASCIN
(Homo
sapiens) 		3 / 3 THR A 367
PRO A 366
THR A 410
 None
 0.78A 316dC-3p40A:
undetectable		 316dC-3p40A:
2.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_D_VIBD223_1
(THIAMINE
PYROPHOSPHOKINASE)		 3p40 NEUROFASCIN
(Homo
sapiens) 		4 / 8 ASP A 206
LEU A 160
LEU A 231
SER A 177
 None
 0.89A 3lm8B-3p40A:
undetectable
3lm8D-3p40A:
undetectable		 3lm8B-3p40A:
19.40
3lm8D-3p40A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)		 3p40 NEUROFASCIN
(Homo
sapiens) 		3 / 3 THR A 367
PRO A 366
THR A 410
 None
 0.82A 4hivD-3p40A:
undetectable		 4hivD-3p40A:
2.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_E_CAME502_0
(CAMPHOR
5-MONOOXYGENASE)		 3p40 NEUROFASCIN
(Homo
sapiens) 		4 / 5 PHE A  82
TYR A 116
THR A  98
ILE A  84
 None
 1.09A 4jx1E-3p40A:
undetectable		 4jx1E-3p40A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 3p40 NEUROFASCIN
(Homo
sapiens) 		5 / 12 ILE A 325
GLY A 323
SER A 324
VAL A 239
PRO A 157
 None
 1.18A 5ergB-3p40A:
undetectable		 5ergB-3p40A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E5Z_A_CCSA106_0
(PROTEIN/NUCLEIC ACID
DEGLYCASE DJ-1)		 3p40 NEUROFASCIN
(Homo
sapiens) 		5 / 10 GLY A 362
ASN A 363
ALA A 335
HIS A 414
GLY A 415
 None
 1.14A 6e5zA-3p40A:
undetectable		 6e5zA-3p40A:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_D_ACTD404_0
(L-LYSINE
3-HYDROXYLASE)		 3p40 NEUROFASCIN
(Homo
sapiens) 		4 / 6 GLN A  46
GLU A  62
HIS A  51
ALA A  48
 None
 1.17A 6f6jC-3p40A:
undetectable
6f6jD-3p40A:
undetectable		 6f6jC-3p40A:
21.55
6f6jD-3p40A:
21.55