SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3p42'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MIC_A_DVAA6_0
(GRAMICIDIN A)		 3p42 PREDICTED PROTEIN
(Escherichia
coli) 		3 / 3 ALA A 224
VAL A 226
TRP A  88
 None
 0.80A 1micA-3p42A:
undetectable
1micB-3p42A:
undetectable		 1micA-3p42A:
13.27
1micB-3p42A:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IW1_A_ASDA1223_1
(CYTOCHROME P450
CYP125)		 3p42 PREDICTED PROTEIN
(Escherichia
coli) 		5 / 12 VAL A 210
SER A 216
ILE A 150
VAL A 190
VAL A 198
 None
 1.24A 3iw1A-3p42A:
undetectable		 3iw1A-3p42A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_B_AERB602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 3p42 PREDICTED PROTEIN
(Escherichia
coli) 		5 / 9 ALA A 159
ASN A 235
ILE A 238
VAL A 239
GLY A 221
 None
 0.96A 4r20B-3p42A:
undetectable		 4r20B-3p42A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB203_0
(HYDROXYNITRILE LYASE)		 3p42 PREDICTED PROTEIN
(Escherichia
coli) 		4 / 4 VAL A 226
ALA A 181
ILE A 100
THR A  99
 None
 1.05A 5e4dB-3p42A:
undetectable		 5e4dB-3p42A:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MXB_A_ML1A222_1
(CLASS 10 PLANT
PATHOGENESIS-RELATED
PROTEIN)		 3p42 PREDICTED PROTEIN
(Escherichia
coli) 		5 / 10 THR A  99
ILE A 100
LEU A  85
GLY A 221
ALA A 183
 None
 0.99A 5mxbA-3p42A:
undetectable		 5mxbA-3p42A:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		 3p42 PREDICTED PROTEIN
(Escherichia
coli) 		5 / 9 SER A 223
ALA A 155
VAL A  96
ALA A 181
VAL A 226
 None
 1.16A 6bklA-3p42A:
undetectable
6bklB-3p42A:
undetectable
6bklC-3p42A:
undetectable
6bklD-3p42A:
undetectable		 6bklA-3p42A:
9.32
6bklB-3p42A:
9.32
6bklC-3p42A:
9.32
6bklD-3p42A:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA819_0
(GEPHYRIN)		 3p42 PREDICTED PROTEIN
(Escherichia
coli) 		3 / 3 ARG A 115
GLY A 195
GLU A 196
 None
 0.58A 6fgdA-3p42A:
undetectable		 6fgdA-3p42A:
21.75