SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3p48'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_1
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 3p48 DEOXYURIDINE
5'-TRIPHOSPHATE
NUCLEOTIDOHYDROLASE
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 111
ARG A  68
ILE A 106
 None
DUP  A 148 (-3.8A)
None
 0.79A 1uobA-3p48A:
undetectable		 1uobA-3p48A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3p48 DEOXYURIDINE
5'-TRIPHOSPHATE
NUCLEOTIDOHYDROLASE
(Saccharomyces
cerevisiae) 		4 / 5 LEU A 117
GLY A  63
ILE A  53
VAL A  92
 None
 0.81A 3wriA-3p48A:
undetectable		 3wriA-3p48A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 3p48 DEOXYURIDINE
5'-TRIPHOSPHATE
NUCLEOTIDOHYDROLASE
(Saccharomyces
cerevisiae) 		4 / 5 LEU A 117
GLY A  63
ILE A  53
VAL A  92
 None
 0.81A 3wriB-3p48A:
undetectable		 3wriB-3p48A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3p48 DEOXYURIDINE
5'-TRIPHOSPHATE
NUCLEOTIDOHYDROLASE
(Saccharomyces
cerevisiae) 		4 / 5 LEU A 117
GLY A  63
ILE A  53
VAL A  92
 None
 0.73A 3wrkA-3p48A:
undetectable		 3wrkA-3p48A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA503_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 3p48 DEOXYURIDINE
5'-TRIPHOSPHATE
NUCLEOTIDOHYDROLASE
(Saccharomyces
cerevisiae) 		4 / 6 ARG A  68
ILE A  65
VAL A  94
LEU A  96
 DUP  A 148 (-3.8A)
None
None
None
 1.04A 4em2A-3p48A:
undetectable		 4em2A-3p48A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_B_GBMB801_1
(PROLINE--TRNA LIGASE)		 3p48 DEOXYURIDINE
5'-TRIPHOSPHATE
NUCLEOTIDOHYDROLASE
(Saccharomyces
cerevisiae) 		5 / 9 TYR A  62
ILE A 116
THR A  79
ILE A  65
GLY A  82
 None
 1.28A 5ifuB-3p48A:
undetectable		 5ifuB-3p48A:
14.37