SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3p52'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_2
(HMG-COA REDUCTASE)		 3p52 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Campylobacter
jejuni) 		4 / 8 GLU A  84
LEU A  66
ALA A  69
LEU A  70
 None
 0.86A 1hwiD-3p52A:
undetectable		 1hwiD-3p52A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_A_RBFA98_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 3p52 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Campylobacter
jejuni) 		5 / 10 LEU A  28
LEU A  30
ILE A  34
PHE A 151
ILE A 154
 None
 1.32A 1i18A-3p52A:
undetectable
1i18B-3p52A:
undetectable		 1i18A-3p52A:
16.67
1i18B-3p52A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 3p52 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Campylobacter
jejuni) 		5 / 10 PHE A 151
ILE A 154
LEU A  28
LEU A  30
ILE A  34
 None
 1.28A 1i18A-3p52A:
undetectable
1i18B-3p52A:
undetectable		 1i18A-3p52A:
16.67
1i18B-3p52A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ERD_A_DESA600_1
(ESTROGEN RECEPTOR
ALPHA)		 3p52 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Campylobacter
jejuni) 		5 / 12 LEU A 205
LEU A 216
LEU A 219
LEU A 223
MET A 231
 None
 1.16A 3erdA-3p52A:
undetectable		 3erdA-3p52A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_A_J3ZA2_1
(ESTROGEN RECEPTOR)		 3p52 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Campylobacter
jejuni) 		5 / 12 LEU A 205
LEU A 216
LEU A 219
LEU A 223
MET A 231
 None
 1.09A 3hm1A-3p52A:
undetectable		 3hm1A-3p52A:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_C_CHDC102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3p52 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Campylobacter
jejuni) 		4 / 7 GLU A 161
LEU A 165
LEU A  38
LEU A  42
 None
 0.56A 4wg0B-3p52A:
undetectable
4wg0C-3p52A:
undetectable		 4wg0B-3p52A:
5.04
4wg0C-3p52A:
5.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_L_CHDL103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3p52 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Campylobacter
jejuni) 		4 / 7 LEU A  38
LEU A  42
GLU A 161
LEU A 165
 None
 0.54A 4wg0L-3p52A:
undetectable
4wg0M-3p52A:
undetectable		 4wg0L-3p52A:
5.04
4wg0M-3p52A:
5.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_A_DESA601_1
(ESTROGEN RECEPTOR)		 3p52 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Campylobacter
jejuni) 		5 / 12 LEU A 205
LEU A 216
LEU A 219
LEU A 223
MET A 231
 None
 1.13A 4zn7A-3p52A:
undetectable		 4zn7A-3p52A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3p52 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Campylobacter
jejuni) 		3 / 3 SER A  87
LEU A  54
MET A  56
 None
None
NO3  A 247 (-4.6A)
 0.76A 5ikrB-3p52A:
undetectable		 5ikrB-3p52A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIG_A_EDTA501_0
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 3p52 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Campylobacter
jejuni) 		4 / 6 THR A   7
ARG A  45
ILE A  14
GLU A  16
 None
 1.26A 5uigA-3p52A:
undetectable		 5uigA-3p52A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNI_A_SAMA401_0
(NSP16 PROTEIN)		 3p52 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Campylobacter
jejuni) 		5 / 12 GLY A  33
ASP A 146
LEU A 147
CYH A 149
ASP A  35
 None
 1.27A 5yniA-3p52A:
undetectable		 5yniA-3p52A:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNM_A_SAMA401_0
(NSP16 PROTEIN)		 3p52 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Campylobacter
jejuni) 		5 / 12 GLY A  33
ASP A 146
LEU A 147
CYH A 149
ASP A  35
 None
 1.26A 5ynmA-3p52A:
undetectable		 5ynmA-3p52A:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 3p52 NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Campylobacter
jejuni) 		5 / 11 SER A  36
VAL A  51
GLY A  25
SER A  23
VAL A 127
 None
 1.39A 6hu9A-3p52A:
undetectable
6hu9E-3p52A:
undetectable
6hu9I-3p52A:
undetectable		 6hu9A-3p52A:
21.93
6hu9E-3p52A:
20.93
6hu9I-3p52A:
15.32