SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3p54'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_1
(TRANSTHYRETIN)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		4 / 7 LEU A 239
SER A  89
SER A 120
THR A 122
 None
 1.08A 1dvxA-3p54A:
undetectable		 1dvxA-3p54A:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_A_CCSA47_0
(GLUTATHIONE
S-TRANSFERASE)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		4 / 7 LEU A 285
GLY A 283
LEU A 280
TYR A 137
 None
 0.94A 1gtiA-3p54A:
undetectable		 1gtiA-3p54A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_B_CCSB47_0
(GLUTATHIONE
S-TRANSFERASE)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		4 / 7 LEU A 285
GLY A 283
LEU A 280
TYR A 137
 None
 0.94A 1gtiB-3p54A:
undetectable		 1gtiB-3p54A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_D_CCSD47_0
(GLUTATHIONE
S-TRANSFERASE)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		4 / 7 LEU A 285
GLY A 283
LEU A 280
TYR A 137
 None
 0.94A 1gtiD-3p54A:
undetectable		 1gtiD-3p54A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_E_CCSE47_0
(GLUTATHIONE
S-TRANSFERASE)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		4 / 7 LEU A 285
GLY A 283
LEU A 280
TYR A 137
 None
 0.94A 1gtiE-3p54A:
undetectable		 1gtiE-3p54A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_A_NIOA221_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		4 / 6 THR A 226
PHE A 218
GLU A  55
GLY A 127
 None
 0.89A 1icuA-3p54A:
undetectable
1icuB-3p54A:
undetectable		 1icuA-3p54A:
20.40
1icuB-3p54A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_B_NIOB219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		4 / 6 PHE A 218
GLU A  55
GLY A 127
THR A 226
 None
 0.86A 1icuA-3p54A:
undetectable
1icuB-3p54A:
undetectable		 1icuA-3p54A:
20.40
1icuB-3p54A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_C_NIOC225_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		4 / 6 THR A 226
PHE A 218
GLU A  55
GLY A 127
 None
 0.83A 1icuC-3p54A:
undetectable
1icuD-3p54A:
undetectable		 1icuC-3p54A:
20.40
1icuD-3p54A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_A_BEZA524_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		4 / 6 THR A 226
PHE A 218
GLU A  55
GLY A 127
 None
 0.96A 1kqbA-3p54A:
undetectable
1kqbB-3p54A:
undetectable		 1kqbA-3p54A:
19.20
1kqbB-3p54A:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_C_BEZC522_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		4 / 6 THR A 226
PHE A 218
GLU A  55
GLY A 127
 None
 0.91A 1kqbC-3p54A:
undetectable
1kqbD-3p54A:
undetectable		 1kqbC-3p54A:
19.20
1kqbD-3p54A:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_D_BEZD523_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		4 / 6 PHE A 218
GLU A  55
GLY A 127
THR A 226
 None
 0.93A 1kqbC-3p54A:
undetectable
1kqbD-3p54A:
undetectable		 1kqbC-3p54A:
19.20
1kqbD-3p54A:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_2
(LIVER
CARBOXYLESTERASE I)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		3 / 3 PHE A 167
LEU A 188
MET A 291
 None
 0.86A 1mx1D-3p54A:
undetectable		 1mx1D-3p54A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_A_SALA710_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		4 / 7 VAL A 186
VAL A  43
LEU A  31
LEU A 188
 None
 0.76A 1pthA-3p54A:
undetectable		 1pthA-3p54A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_B_SALB711_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		4 / 7 VAL A 186
VAL A  43
LEU A  31
LEU A 188
 None
 0.75A 1pthB-3p54A:
undetectable		 1pthB-3p54A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_A_SAMA301_0
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		5 / 12 ILE A  33
ALA A 164
ILE A 141
THR A  32
GLU A  13
 None
 1.44A 1vq1A-3p54A:
undetectable		 1vq1A-3p54A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_D_ASDD1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		4 / 7 GLY A 145
LEU A  41
PHE A 142
PHE A   1
 None
 0.98A 2vctD-3p54A:
undetectable		 2vctD-3p54A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		5 / 12 ASP A  42
LEU A 371
GLY A 145
HIS A 144
PHE A   1
 None
 1.36A 2zj0B-3p54A:
undetectable		 2zj0B-3p54A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_C_2FAC500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		5 / 12 ASP A  42
LEU A 371
GLY A 145
HIS A 144
PHE A   1
 None
 1.35A 2zj0C-3p54A:
undetectable		 2zj0C-3p54A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_B_ADNB500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		5 / 12 ASP A  42
LEU A 371
GLY A 145
HIS A 144
PHE A   1
 None
 1.32A 3ce6B-3p54A:
undetectable		 3ce6B-3p54A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_1
(ADENOSYLHOMOCYSTEINA
SE)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		5 / 12 ASP A  42
LEU A 371
GLY A 145
HIS A 144
PHE A   1
 None
 1.27A 3glqA-3p54A:
undetectable		 3glqA-3p54A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_1
(ADENOSYLHOMOCYSTEINA
SE)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		5 / 12 ASP A  42
LEU A 371
GLY A 145
HIS A 144
PHE A   1
 None
 1.33A 3glqB-3p54A:
undetectable		 3glqB-3p54A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		5 / 12 ASP A  42
LEU A 371
GLY A 145
HIS A 144
PHE A   1
 None
 1.32A 3n58A-3p54A:
undetectable		 3n58A-3p54A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_C_ADNC500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		5 / 12 ASP A  42
LEU A 371
GLY A 145
HIS A 144
PHE A   1
 None
 1.39A 3n58C-3p54A:
undetectable		 3n58C-3p54A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_C_FLPC701_1
(CYCLOOXYGENASE-2)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		5 / 12 VAL A 186
VAL A  43
LEU A  31
VAL A  21
LEU A 188
 None
 0.88A 3pghC-3p54A:
undetectable		 3pghC-3p54A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		4 / 5 HIS A 144
THR A 147
GLU A 373
ASP A 316
 None
 1.28A 3tm4A-3p54A:
undetectable		 3tm4A-3p54A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		4 / 5 HIS A 144
THR A 147
GLU A 373
ASP A 316
 None
 1.31A 3tm4B-3p54A:
undetectable		 3tm4B-3p54A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_2
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		4 / 6 GLU A  49
ILE A  48
ASN A  47
VAL A 176
 None
 1.11A 4ejwB-3p54A:
undetectable		 4ejwB-3p54A:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		4 / 7 ILE A  33
THR A  40
VAL A  24
ASP A  28
 None
 1.18A 4iarA-3p54A:
undetectable		 4iarA-3p54A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAE_A_NIZA804_1
(CATALASE-PEROXIDASE)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		4 / 6 ASP A  42
LEU A   4
HIS A 144
THR A 356
 None
 1.15A 4paeA-3p54A:
undetectable		 4paeA-3p54A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GLM_A_ACTA613_0
(GLYCOSIDE HYDROLASE
FAMILY 43)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		3 / 3 ASP A 332
SER A 329
TYR A 328
 None
 0.82A 5glmA-3p54A:
undetectable		 5glmA-3p54A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSP_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		4 / 7 VAL A  65
ILE A  68
VAL A  91
ALA A 117
 None
 0.70A 5ospA-3p54A:
undetectable		 5ospA-3p54A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRX_A_H8GA1201_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		5 / 12 ALA A 157
PHE A 142
ASN A   2
VAL A 143
TYR A 183
 None
 1.27A 6drxA-3p54A:
undetectable		 6drxA-3p54A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_A_ADNA502_1
(-)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		5 / 12 ASP A  42
LEU A 371
GLY A 145
HIS A 144
PHE A   1
 None
 1.26A 6f3mA-3p54A:
undetectable		 6f3mA-3p54A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_C_ADNC502_1
(-)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		5 / 12 ASP A  42
LEU A 371
GLY A 145
HIS A 144
PHE A   1
 None
 1.26A 6f3mC-3p54A:
undetectable		 6f3mC-3p54A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_A_ADNA505_1
(-)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		5 / 12 ASP A  42
LEU A 371
GLY A 145
HIS A 144
PHE A   1
 None
 1.32A 6f3nA-3p54A:
undetectable		 6f3nA-3p54A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_C_ADNC505_1
(-)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		5 / 12 ASP A  42
LEU A 371
GLY A 145
HIS A 144
PHE A   1
 None
 1.24A 6f3nC-3p54A:
undetectable		 6f3nC-3p54A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_D_ADND506_1
(-)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		5 / 12 ASP A  42
LEU A 371
GLY A 145
HIS A 144
PHE A   1
 None
 1.32A 6f3nD-3p54A:
undetectable		 6f3nD-3p54A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_1
(-)		 3p54 ENVELOPE
GLYCOPROTEIN
(Japanese
encephalitis
virus) 		5 / 12 ASP A  42
LEU A 371
GLY A 145
HIS A 144
PHE A   1
 None
 1.25A 6gbnB-3p54A:
undetectable		 6gbnB-3p54A:
23.91