SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3p5p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_2
(VITAMIN D NUCLEAR
RECEPTOR)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		4 / 6 LEU A 311
ILE A 236
ARG A 266
TYR A 140
 None
 1.08A 1db1A-3p5pA:
2.1		 1db1A-3p5pA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_B_ESTB1600_1
(ESTROGEN RECEPTOR)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		5 / 12 MET A 615
GLU A 696
LEU A 622
MET A 647
ILE A 643
 None
 1.23A 1g50B-3p5pA:
undetectable		 1g50B-3p5pA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_A_117A2_2
(HMG-COA REDUCTASE)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		5 / 11 GLU A 804
SER A 750
LEU A 751
ALA A 711
LEU A 707
 None
 1.44A 1hwkB-3p5pA:
undetectable		 1hwkB-3p5pA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_B_117B1_1
(HMG-COA REDUCTASE)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		5 / 11 GLU A 804
SER A 750
LEU A 751
ALA A 711
LEU A 707
 None
 1.46A 1hwkA-3p5pA:
undetectable		 1hwkA-3p5pA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_C_117C4_2
(HMG-COA REDUCTASE)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		5 / 11 GLU A 804
SER A 750
LEU A 751
ALA A 711
LEU A 707
 None
 1.45A 1hwkD-3p5pA:
undetectable		 1hwkD-3p5pA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_D_117D3_1
(HMG-COA REDUCTASE)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		5 / 11 GLU A 804
SER A 750
LEU A 751
ALA A 711
LEU A 707
 None
 1.46A 1hwkC-3p5pA:
undetectable		 1hwkC-3p5pA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ISM_B_NCAB305_0
(BONE MARROW STROMAL
CELL ANTIGEN 1)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		4 / 7 LEU A 640
SER A 638
ASP A 636
PHE A 628
 None
 1.05A 1ismB-3p5pA:
undetectable		 1ismB-3p5pA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KW0_A_H4BA429_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		5 / 12 VAL A 145
LEU A 336
LEU A 333
SER A 309
THR A 142
 None
 1.37A 1kw0A-3p5pA:
undetectable		 1kw0A-3p5pA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_B_DMEB996_1
(ACETYLCHOLINESTERASE)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		4 / 6 GLU A 765
ILE A 712
TYR A 684
GLY A 717
 MG  A 901 ( 2.6A)
None
None
None
 1.08A 1maaB-3p5pA:
2.6
1maaD-3p5pA:
2.9		 1maaB-3p5pA:
21.17
1maaD-3p5pA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_A_SAMA200_0
(METHIONINE REPRESSOR)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		5 / 11 ARG A 222
LEU A 252
PRO A 253
ALA A 214
PHE A 216
 None
 1.18A 1mjqA-3p5pA:
1.0
1mjqB-3p5pA:
undetectable		 1mjqA-3p5pA:
9.40
1mjqB-3p5pA:
9.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_G_SAMG199_0
(METHIONINE REPRESSOR)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		5 / 10 ARG A 222
LEU A 252
PRO A 253
ALA A 214
PHE A 216
 None
 1.16A 1mjqG-3p5pA:
undetectable
1mjqH-3p5pA:
undetectable		 1mjqG-3p5pA:
9.40
1mjqH-3p5pA:
9.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMT_A_H4BA1426_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		5 / 11 VAL A 145
LEU A 336
LEU A 333
SER A 309
THR A 142
 None
 1.35A 1mmtA-3p5pA:
undetectable		 1mmtA-3p5pA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_A_DESA459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		5 / 12 LEU A 562
LEU A 559
VAL A 855
TYR A 856
ILE A 600
 None
 1.05A 1s9pA-3p5pA:
2.1		 1s9pA-3p5pA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		4 / 7 MET A 414
ARG A 508
ASN A 826
GLU A 592
 EDO  A 921 (-3.6A)
None
EDO  A 921 (-3.3A)
None
 1.38A 1t9wA-3p5pA:
4.4		 1t9wA-3p5pA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_1
(MINERALOCORTICOID
RECEPTOR)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		5 / 12 LEU A 242
GLN A 235
SER A 231
LEU A 230
LEU A 191
 None
 1.44A 1ya3B-3p5pA:
undetectable		 1ya3B-3p5pA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_B_ACTB2002_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		4 / 6 SER A 313
ALA A 315
SER A 316
ASN A 286
 None
 1.16A 1yvpB-3p5pA:
2.3		 1yvpB-3p5pA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		5 / 12 HIS A 385
ILE A 391
GLY A 408
LEU A 412
SER A 349
 None
 1.25A 1zq9A-3p5pA:
undetectable		 1zq9A-3p5pA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_F_SAMF301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		3 / 3 LYS A 483
ASP A 228
CYH A 187
 None
 1.38A 2br4F-3p5pA:
undetectable		 2br4F-3p5pA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_B_ACTB141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		3 / 3 PRO A 507
ASN A 826
ARG A 828
 None
EDO  A 921 (-3.3A)
None
 0.82A 2qeuB-3p5pA:
2.5		 2qeuB-3p5pA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_2
(ESTROGEN RECEPTOR)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		4 / 5 LEU A 407
MET A 414
LEU A 457
HIS A 364
 None
EDO  A 921 (-3.6A)
None
None
 1.32A 2qxsA-3p5pA:
2.3		 2qxsA-3p5pA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		4 / 5 LEU A 755
ILE A 700
TRP A 694
TYR A 778
 None
 1.36A 2zlcA-3p5pA:
1.6		 2zlcA-3p5pA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_1
(UNCHARACTERIZED
PROTEIN MJ1557)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		3 / 3 MET A 571
GLU A 660
ASN A 662
 None
 1.11A 3a27A-3p5pA:
undetectable		 3a27A-3p5pA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_B_NIOB5661_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		4 / 8 ILE A 391
THR A 411
LEU A 412
ALA A 454
 None
 0.68A 3hrdA-3p5pA:
undetectable
3hrdB-3p5pA:
undetectable		 3hrdA-3p5pA:
18.68
3hrdB-3p5pA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_B_PZIB802_0
(GLUTAMATE RECEPTOR 2)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		3 / 3 SER A 313
ASP A 141
ASN A 195
 None
 0.96A 3lsfB-3p5pA:
undetectable
3lsfE-3p5pA:
undetectable		 3lsfB-3p5pA:
15.02
3lsfE-3p5pA:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_E_PZIE802_0
(GLUTAMATE RECEPTOR 2)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		3 / 3 ASP A 141
ASN A 195
SER A 313
 None
 0.95A 3lsfB-3p5pA:
undetectable
3lsfE-3p5pA:
undetectable		 3lsfB-3p5pA:
15.02
3lsfE-3p5pA:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA402_1
(HIV-1 PROTEASE)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		4 / 5 ARG A 754
LEU A 707
PRO A 701
ASP A 758
 A3C  A 911 (-3.4A)
None
None
None
 1.16A 3ufnA-3p5pA:
undetectable
3ufnB-3p5pA:
undetectable		 3ufnA-3p5pA:
9.82
3ufnB-3p5pA:
9.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		5 / 12 ILE A 236
SER A 313
VAL A 145
ILE A 280
PHE A 332
 None
 1.03A 3w67B-3p5pA:
undetectable		 3w67B-3p5pA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		5 / 12 PHE A 834
TYR A 856
VAL A 855
ALA A 589
SER A 588
 A3C  A 912 ( 3.8A)
None
None
None
None
 1.21A 4a84A-3p5pA:
undetectable		 4a84A-3p5pA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7B_C_ACTC513_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		3 / 3 TYR A 381
HIS A 385
ARG A 384
 None
 0.94A 4e7bC-3p5pA:
undetectable		 4e7bC-3p5pA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G8Z_X_TOPX301_1
(DIHYDROFOLATE
REDUCTASE)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		5 / 10 ILE A 375
ALA A 378
LEU A 130
SER A 534
ILE A 362
 None
 1.25A 4g8zX-3p5pA:
undetectable		 4g8zX-3p5pA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		4 / 7 ILE A 824
LEU A 827
PHE A 602
GLY A 606
 None
None
A3C  A 911 ( 4.8A)
A3C  A 911 (-3.8A)
 0.91A 4hbfA-3p5pA:
undetectable		 4hbfA-3p5pA:
6.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1X_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		4 / 8 LEU A 476
TYR A 475
VAL A 498
LEU A 402
 None
 1.01A 4l1xA-3p5pA:
undetectable		 4l1xA-3p5pA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_F_FOLF301_1
(FOLATE RECEPTOR
ALPHA)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		3 / 3 ASP A 188
TRP A 167
SER A 177
 None
 0.96A 4lrhF-3p5pA:
undetectable		 4lrhF-3p5pA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_2
(ESTROGEN RECEPTOR)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		4 / 5 LEU A 407
MET A 414
LEU A 457
HIS A 364
 None
EDO  A 921 (-3.6A)
None
None
 1.36A 4xi3B-3p5pA:
undetectable		 4xi3B-3p5pA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERM_A_210A401_1
(FUSICOCCADIENE
SYNTHASE)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		5 / 10 ASP A 613
ARG A 754
VAL A 714
ASN A 757
GLU A 765
 A3C  A 911 ( 3.8A)
A3C  A 911 (-3.4A)
A3C  A 911 (-4.8A)
MG  A 901 ( 2.7A)
MG  A 901 ( 2.6A)
 0.83A 5ermA-3p5pA:
10.2		 5ermA-3p5pA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERM_B_210B704_1
(FUSICOCCADIENE
SYNTHASE)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		5 / 9 ASP A 613
ARG A 754
VAL A 714
ASN A 757
GLU A 765
 A3C  A 911 ( 3.8A)
A3C  A 911 (-3.4A)
A3C  A 911 (-4.8A)
MG  A 901 ( 2.7A)
MG  A 901 ( 2.6A)
 0.81A 5ermB-3p5pA:
16.4		 5ermB-3p5pA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I75_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		5 / 12 TYR A 684
TYR A 835
SER A 713
GLY A 715
LEU A 716
 None
A3C  A 912 ( 4.4A)
None
A3C  A 911 ( 4.7A)
None
 1.20A 5i75A-3p5pA:
2.2		 5i75A-3p5pA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC3_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		4 / 5 LEU A 721
LEU A 725
MET A 658
TYR A 684
 None
 1.41A 5uc3A-3p5pA:
1.9		 5uc3A-3p5pA:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_2
(RIBOFLAVIN LYASE)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		4 / 5 GLN A 212
ASP A 175
SER A 177
ARG A 189
 None
 1.34A 5w4zA-3p5pA:
undetectable		 5w4zA-3p5pA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_A_TKTA508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		4 / 8 ASP A 233
ILE A 237
ASN A 192
TYR A 530
 None
 1.17A 6hisA-3p5pA:
2.1
6hisB-3p5pA:
2.1		 6hisA-3p5pA:
8.26
6hisB-3p5pA:
8.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_B_TKTB508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		4 / 8 ASP A 233
ILE A 237
ASN A 192
TYR A 530
 None
 1.17A 6hisB-3p5pA:
2.1
6hisC-3p5pA:
2.1		 6hisB-3p5pA:
8.26
6hisC-3p5pA:
8.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_C_TKTC508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		4 / 8 ASP A 233
ILE A 237
ASN A 192
TYR A 530
 None
 1.18A 6hisC-3p5pA:
2.1
6hisD-3p5pA:
2.1		 6hisC-3p5pA:
8.26
6hisD-3p5pA:
8.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_D_TKTD501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		4 / 8 ASP A 233
ILE A 237
ASN A 192
TYR A 530
 None
 1.16A 6hisD-3p5pA:
2.1
6hisE-3p5pA:
2.1		 6hisD-3p5pA:
8.26
6hisE-3p5pA:
8.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_E_TKTE501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3p5p TAXADIENE SYNTHASE
(Taxus
brevifolia) 		4 / 8 ASN A 192
TYR A 530
ASP A 233
ILE A 237
 None
 1.18A 6hisA-3p5pA:
2.1
6hisE-3p5pA:
2.1		 6hisA-3p5pA:
8.26
6hisE-3p5pA:
8.26