SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3p6l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		 3p6l SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		5 / 12 LEU A  93
ALA A  94
THR A 104
LEU A 127
PHE A  78
 None
 1.17A 1og5A-3p6lA:
undetectable		 1og5A-3p6lA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 3p6l SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		4 / 8 GLY A 103
GLN A  37
ILE A 101
VAL A 102
 None
CIT  A 303 ( 3.9A)
None
None
 0.97A 1rxcB-3p6lA:
undetectable		 1rxcB-3p6lA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_C_URFC2081_1
(URIDINE
PHOSPHORYLASE)		 3p6l SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		4 / 7 GLY A 103
GLN A  37
ILE A 101
VAL A 102
 None
CIT  A 303 ( 3.9A)
None
None
 0.99A 1rxcC-3p6lA:
undetectable		 1rxcC-3p6lA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)		 3p6l SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		4 / 7 GLY A 103
GLN A  37
ILE A 101
VAL A 102
 None
CIT  A 303 ( 3.9A)
None
None
 1.06A 1rxcD-3p6lA:
undetectable		 1rxcD-3p6lA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)		 3p6l SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		4 / 8 GLY A 103
GLN A  37
ILE A 101
VAL A 102
 None
CIT  A 303 ( 3.9A)
None
None
 0.99A 1rxcE-3p6lA:
undetectable		 1rxcE-3p6lA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 3p6l SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		4 / 7 GLY A 103
GLN A  37
ILE A 101
VAL A 102
 None
CIT  A 303 ( 3.9A)
None
None
 1.00A 1rxcF-3p6lA:
undetectable		 1rxcF-3p6lA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)		 3p6l SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		4 / 8 GLY A 103
GLN A  37
ILE A 101
VAL A 102
 None
CIT  A 303 ( 3.9A)
None
None
 0.97A 1rxcI-3p6lA:
undetectable		 1rxcI-3p6lA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 3p6l SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		4 / 8 GLY A 103
GLN A  37
ILE A 101
VAL A 102
 None
CIT  A 303 ( 3.9A)
None
None
 0.97A 1rxcK-3p6lA:
undetectable		 1rxcK-3p6lA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 3p6l SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		4 / 7 GLY A 103
GLN A  37
ILE A 101
VAL A 102
 None
CIT  A 303 ( 3.9A)
None
None
 1.01A 1rxcL-3p6lA:
undetectable		 1rxcL-3p6lA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_2
(PHOSPHOLIPASE A2)		 3p6l SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		4 / 6 VAL A 266
LYS A 270
GLN A 274
LEU A 242
 None
 1.09A 3bjwE-3p6lA:
undetectable		 3bjwE-3p6lA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HKU_A_TORA300_2
(CARBONIC ANHYDRASE 2)		 3p6l SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		3 / 3 GLU A  62
HIS A 212
THR A 131
 None
CIT  A 303 (-4.6A)
None
 0.74A 3hkuA-3p6lA:
undetectable		 3hkuA-3p6lA:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 3p6l SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		4 / 6 GLY A 103
GLN A  37
ILE A 101
VAL A 102
 None
CIT  A 303 ( 3.9A)
None
None
 1.01A 3kvvB-3p6lA:
undetectable		 3kvvB-3p6lA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 3p6l SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		4 / 6 GLY A 103
GLN A  37
ILE A 101
VAL A 102
 None
CIT  A 303 ( 3.9A)
None
None
 1.02A 3kvvC-3p6lA:
undetectable		 3kvvC-3p6lA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_D_URFD254_1
(URIDINE
PHOSPHORYLASE)		 3p6l SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		4 / 6 GLY A 103
GLN A  37
ILE A 101
VAL A 102
 None
CIT  A 303 ( 3.9A)
None
None
 0.97A 3kvvD-3p6lA:
undetectable		 3kvvD-3p6lA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 3p6l SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		4 / 6 GLY A 103
GLN A  37
ILE A 101
VAL A 102
 None
CIT  A 303 ( 3.9A)
None
None
 1.01A 3kvvE-3p6lA:
undetectable		 3kvvE-3p6lA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 3p6l SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		4 / 6 GLY A 103
GLN A  37
ILE A 101
VAL A 102
 None
CIT  A 303 ( 3.9A)
None
None
 0.99A 3kvvF-3p6lA:
undetectable		 3kvvF-3p6lA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3p6l SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		3 / 3 VAL A 187
SER A 185
LEU A 201
 None
 0.74A 3n8xA-3p6lA:
undetectable		 3n8xA-3p6lA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 3p6l SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		4 / 8 GLY A 103
GLN A  37
ILE A 101
VAL A 102
 None
CIT  A 303 ( 3.9A)
None
None
 0.99A 4e1vA-3p6lA:
undetectable		 4e1vA-3p6lA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 3p6l SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		4 / 7 GLY A 103
GLN A  37
ILE A 101
VAL A 102
 None
CIT  A 303 ( 3.9A)
None
None
 0.97A 4e1vB-3p6lA:
undetectable		 4e1vB-3p6lA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)		 3p6l SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		4 / 6 GLY A 103
GLN A  37
ILE A 101
VAL A 102
 None
CIT  A 303 ( 3.9A)
None
None
 1.01A 4e1vF-3p6lA:
undetectable		 4e1vF-3p6lA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_A_ACTA1002_0
(ACTIN, ALPHA
SKELETAL MUSCLE
FORMIN-LIKE PROTEIN
3)		 3p6l SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		4 / 5 THR A 131
GLN A  37
GLU A  62
THR A 104
 None
CIT  A 303 ( 3.9A)
None
None
 1.20A 4eahA-3p6lA:
1.1
4eahE-3p6lA:
0.0
4eahG-3p6lA:
undetectable		 4eahA-3p6lA:
22.01
4eahE-3p6lA:
22.01
4eahG-3p6lA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3p6l SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		5 / 12 ILE A 256
GLY A  35
ILE A  99
ILE A 101
LEU A  46
 None
 1.04A 4mwzA-3p6lA:
undetectable		 4mwzA-3p6lA:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		 3p6l SUGAR PHOSPHATE
ISOMERASE/EPIMERASE
(Parabacteroides
distasonis) 		3 / 3 ASN A 157
SER A 183
SER A 154
 None
 0.74A 5gsnA-3p6lA:
undetectable		 5gsnA-3p6lA:
20.04