SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3p7x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_A_BEZA1162_0
(PEROXIREDOXIN 5)		 3p7x PROBABLE THIOL
PEROXIDASE
(Staphylococcus
aureus) 		5 / 10 PRO A  53
THR A  57
CYH A  60
LEU A 123
ARG A 128
 None
 0.92A 1h4oA-3p7xA:
18.7
1h4oB-3p7xA:
18.8		 1h4oA-3p7xA:
26.09
1h4oB-3p7xA:
26.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 3p7x PROBABLE THIOL
PEROXIDASE
(Staphylococcus
aureus) 		4 / 8 PRO A  53
THR A  57
CYH A  60
ARG A 128
 None
 0.52A 1h4oB-3p7xA:
18.8		 1h4oB-3p7xA:
26.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 3p7x PROBABLE THIOL
PEROXIDASE
(Staphylococcus
aureus) 		4 / 8 THR A  57
CYH A  60
ARG A 128
THR A 149
 None
 0.70A 1h4oB-3p7xA:
18.8		 1h4oB-3p7xA:
26.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_D_BEZD1162_0
(PEROXIREDOXIN 5)		 3p7x PROBABLE THIOL
PEROXIDASE
(Staphylococcus
aureus) 		5 / 9 PRO A  53
THR A  57
CYH A  60
LEU A 123
ARG A 128
 None
 0.90A 1h4oD-3p7xA:
18.7		 1h4oD-3p7xA:
26.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_F_BEZF1162_0
(PEROXIREDOXIN 5)		 3p7x PROBABLE THIOL
PEROXIDASE
(Staphylococcus
aureus) 		5 / 9 PRO A  53
THR A  57
CYH A  60
LEU A 123
ARG A 128
 None
 0.90A 1h4oF-3p7xA:
18.7		 1h4oF-3p7xA:
26.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)		 3p7x PROBABLE THIOL
PEROXIDASE
(Staphylococcus
aureus) 		5 / 8 PRO A  53
THR A  57
CYH A  60
LEU A 123
ARG A 128
 None
 0.92A 1h4oG-3p7xA:
18.7		 1h4oG-3p7xA:
26.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_H_BEZH1162_0
(PEROXIREDOXIN 5)		 3p7x PROBABLE THIOL
PEROXIDASE
(Staphylococcus
aureus) 		5 / 9 PRO A  53
THR A  57
CYH A  60
LEU A 123
ARG A 128
 None
 0.86A 1h4oH-3p7xA:
18.7		 1h4oH-3p7xA:
26.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HD2_A_BEZA201_0
(PEROXIREDOXIN 5
RESIDUES 54-214)		 3p7x PROBABLE THIOL
PEROXIDASE
(Staphylococcus
aureus) 		5 / 9 PRO A  53
THR A  57
CYH A  60
LEU A 123
ARG A 128
 None
 0.91A 1hd2A-3p7xA:
18.9		 1hd2A-3p7xA:
26.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 3p7x PROBABLE THIOL
PEROXIDASE
(Staphylococcus
aureus) 		4 / 8 PRO A  53
THR A  57
CYH A  60
ARG A 128
 None
 0.48A 1oc3A-3p7xA:
18.8		 1oc3A-3p7xA:
27.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 3p7x PROBABLE THIOL
PEROXIDASE
(Staphylococcus
aureus) 		4 / 8 THR A  57
CYH A  60
ARG A 128
THR A 149
 None
 0.62A 1oc3A-3p7xA:
18.8		 1oc3A-3p7xA:
27.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_B_BEZB201_0
(PEROXIREDOXIN 5)		 3p7x PROBABLE THIOL
PEROXIDASE
(Staphylococcus
aureus) 		5 / 9 PRO A  53
THR A  57
CYH A  60
LEU A 123
ARG A 128
 None
 0.86A 1oc3B-3p7xA:
18.5		 1oc3B-3p7xA:
27.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)		 3p7x PROBABLE THIOL
PEROXIDASE
(Staphylococcus
aureus) 		4 / 8 PRO A  53
THR A  57
VAL A  59
ARG A 128
 None
 0.41A 2v32C-3p7xA:
16.3
2v32D-3p7xA:
17.6		 2v32C-3p7xA:
21.58
2v32D-3p7xA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_C_BEZC1218_0
(PEROXIREDOXIN 6.)		 3p7x PROBABLE THIOL
PEROXIDASE
(Staphylococcus
aureus) 		4 / 8 PRO A  53
THR A  57
VAL A  59
ARG A 128
 None
 0.44A 2v41C-3p7xA:
17.6
2v41D-3p7xA:
17.8		 2v41C-3p7xA:
21.58
2v41D-3p7xA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_D_BEZD1222_0
(PEROXIREDOXIN 6.)		 3p7x PROBABLE THIOL
PEROXIDASE
(Staphylococcus
aureus) 		4 / 8 PRO A  53
THR A  57
VAL A  59
ARG A 128
 None
 0.39A 2v41C-3p7xA:
17.6
2v41D-3p7xA:
17.8		 2v41C-3p7xA:
21.58
2v41D-3p7xA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_H_BEZH1222_0
(PEROXIREDOXIN 6.)		 3p7x PROBABLE THIOL
PEROXIDASE
(Staphylococcus
aureus) 		4 / 8 PRO A  53
THR A  57
VAL A  59
ARG A 128
 None
 0.40A 2v41G-3p7xA:
16.3
2v41H-3p7xA:
16.3		 2v41G-3p7xA:
21.58
2v41H-3p7xA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_A_BEZA1162_0
(PEROXIREDOXIN-5)		 3p7x PROBABLE THIOL
PEROXIDASE
(Staphylococcus
aureus) 		5 / 10 PRO A  53
THR A  57
CYH A  60
LEU A 123
ARG A 128
 None
 0.83A 2vl2A-3p7xA:
18.9
2vl2C-3p7xA:
16.2		 2vl2A-3p7xA:
27.17
2vl2C-3p7xA:
27.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_2
(ANGIOTENSIN
CONVERTING ENZYME)		 3p7x PROBABLE THIOL
PEROXIDASE
(Staphylococcus
aureus) 		3 / 3 SER A  54
THR A  80
PHE A 154
 None
 0.64A 2x91A-3p7xA:
undetectable		 2x91A-3p7xA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB303_0
(DISULFIDE
INTERCHANGE PROTEIN)		 3p7x PROBABLE THIOL
PEROXIDASE
(Staphylococcus
aureus) 		4 / 4 LEU A  13
ALA A 129
VAL A  51
PRO A  53
 SO4  A 165 (-3.7A)
None
None
None
 0.77A 3gv1B-3p7xA:
3.8		 3gv1B-3p7xA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EU8_B_010B6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
MAIN PROTEASE)		 3p7x PROBABLE THIOL
PEROXIDASE
(Staphylococcus
aureus) 		4 / 5 ASN A  68
LEU A  98
THR A  80
CYH A  93
 None
 1.05A 5eu8A-3p7xA:
undetectable		 5eu8A-3p7xA:
20.85