SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3p8a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3003_1
(SERUM ALBUMIN)		 3p8a UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 6 HIS A  54
LYS A  82
ALA A  85
VAL A  75
 None
 0.91A 1hk1A-3p8aA:
undetectable		 1hk1A-3p8aA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2501_0
(FERROCHELATASE)		 3p8a UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 12 LEU A 112
PHE A 212
LEU A 228
MET A 214
VAL A 196
 None
 1.31A 1hrkB-3p8aA:
undetectable		 1hrkB-3p8aA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA996_1
(GLUCOAMYLASE GLU1)		 3p8a UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 7 ASN A  68
ASP A  26
GLY A  63
TYR A  64
 None
 0.87A 2f6dA-3p8aA:
undetectable		 2f6dA-3p8aA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_B_CHDB701_0
(FERROCHELATASE)		 3p8a UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		3 / 3 LYS A  55
GLY A 133
PRO A 134
 None
 0.97A 2hreB-3p8aA:
undetectable		 2hreB-3p8aA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_B_LDPB502_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 3p8a UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 5 GLN A 186
PHE A 189
PHE A 270
GLY A  42
 None
 1.01A 2qmzA-3p8aA:
undetectable
2qmzB-3p8aA:
undetectable		 2qmzA-3p8aA:
19.33
2qmzB-3p8aA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3p8a UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 6 GLY A  42
GLN A 186
PHE A 189
PHE A 270
 None
 1.03A 2qx6A-3p8aA:
undetectable
2qx6B-3p8aA:
undetectable		 2qx6A-3p8aA:
19.33
2qx6B-3p8aA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		 3p8a UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 6 TYR A 184
TYR A  69
PHE A  40
LEU A  72
 None
GOL  A 275 (-4.5A)
None
None
 0.93A 2w98A-3p8aA:
undetectable
2w98B-3p8aA:
undetectable		 2w98A-3p8aA:
20.22
2w98B-3p8aA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB6_0
(FERROCHELATASE)		 3p8a UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 12 LEU A 112
PHE A 212
LEU A 228
MET A 214
VAL A 196
 None
 1.32A 3aqiB-3p8aA:
undetectable		 3aqiB-3p8aA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3p8a UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 12 LEU A 112
PHE A 212
LEU A 228
MET A 214
VAL A 196
 None
 1.33A 3w1wA-3p8aA:
undetectable		 3w1wA-3p8aA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_C_ZPCC1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3p8a UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 12 PHE A 107
VAL A 248
ILE A 191
ILE A 162
HIS A  30
 None
None
None
CL  A 278 (-4.8A)
None
 1.35A 4a97B-3p8aA:
undetectable
4a97C-3p8aA:
undetectable		 4a97B-3p8aA:
21.15
4a97C-3p8aA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_C_ACTC506_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3p8a UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 5 ARG A 264
ILE A  32
HIS A  30
GLY A 106
 None
 1.50A 4e7cC-3p8aA:
undetectable		 4e7cC-3p8aA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_B_CLQB303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3p8a UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 11 GLN A 186
PHE A 189
ILE A  45
PHE A 270
GLY A  42
 None
 1.32A 4fglA-3p8aA:
undetectable
4fglB-3p8aA:
undetectable		 4fglA-3p8aA:
19.60
4fglB-3p8aA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K38_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 3p8a UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 12 PHE A  40
TYR A 268
GLU A 271
ILE A  28
LEU A  72
 None
 1.38A 4k38B-3p8aA:
undetectable		 4k38B-3p8aA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_A_ASCA303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 3p8a UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 7 PHE A 166
ILE A 168
ASN A  60
ARG A 177
 None
None
GOL  A 275 (-3.5A)
None
 0.98A 4o7gA-3p8aA:
undetectable
4o7gB-3p8aA:
undetectable		 4o7gA-3p8aA:
20.07
4o7gB-3p8aA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 3p8a UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		3 / 3 ASP A 160
ASN A 109
SER A 206
 None
 0.83A 4obwA-3p8aA:
undetectable		 4obwA-3p8aA:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2T_A_ACTA108_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 3p8a UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		3 / 3 VAL A 147
THR A 141
ARG A 139
 None
None
GOL  A 275 (-3.5A)
 0.80A 5b2tB-3p8aA:
undetectable		 5b2tB-3p8aA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3p8a UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 12 ILE A  65
GLY A  63
GLU A 271
SER A 260
ILE A 261
 None
 1.23A 5igyA-3p8aA:
undetectable		 5igyA-3p8aA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3p8a UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 8 PHE A  40
ARG A 264
ILE A 263
GLY A 265
 None
 1.00A 5nzxA-3p8aA:
undetectable		 5nzxA-3p8aA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3p8a UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 7 PHE A  40
ARG A 264
ILE A 263
GLY A 265
 None
 0.80A 5nzyA-3p8aA:
undetectable		 5nzyA-3p8aA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3p8a UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 12 ILE A 261
TYR A 268
GLY A  42
LEU A  47
HIS A  48
 None
 1.40A 5v5zA-3p8aA:
undetectable		 5v5zA-3p8aA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA411_0
(UNCHARACTERIZED
PROTEIN KDOO)		 3p8a UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		3 / 3 LYS A 180
LEU A 181
ARG A 177
 None
 0.65A 5yw0A-3p8aA:
undetectable		 5yw0A-3p8aA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW2_A_ACTA511_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 3p8a UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		3 / 3 ARG A 269
ILE A 267
SER A 260
 None
 0.88A 5zw2A-3p8aA:
undetectable		 5zw2A-3p8aA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9K_F_ACTF802_0
(UNCHARACTERIZED
PROTEIN)		 3p8a UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		3 / 3 TYR A 103
ALA A  85
LEU A  81
 None
 0.73A 6d9kF-3p8aA:
undetectable		 6d9kF-3p8aA:
16.37