SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3p8l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_2
(ESTROGEN RECEPTOR)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		4 / 6 LEU A 180
LEU A  79
LEU A 290
LEU A 287
 None
 0.77A 1errA-3p8lA:
undetectable		 1errA-3p8lA:
21.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_A_RISA901_1
(GERANYLTRANSTRANSFER
ASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		6 / 11 SER A  78
LEU A  79
ASP A  88
ARG A  93
GLN A 153
THR A 177
 None
 0.74A 1rqjA-3p8lA:
34.0		 1rqjA-3p8lA:
42.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_B_RISB903_1
(GERANYLTRANSTRANSFER
ASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		6 / 11 SER A  78
LEU A  79
ASP A  88
ARG A  93
GLN A 153
THR A 177
 None
 0.74A 1rqjB-3p8lA:
34.1		 1rqjB-3p8lA:
42.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		4 / 8 THR A 177
GLY A 152
GLN A 153
VAL A 172
 None
 0.96A 1rxcB-3p8lA:
undetectable		 1rxcB-3p8lA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		4 / 8 THR A 177
GLY A 152
GLN A 153
VAL A 172
 None
 0.99A 1rxcE-3p8lA:
undetectable		 1rxcE-3p8lA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YQ7_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 11 LEU A  79
ASP A  82
ASP A  88
GLN A 153
THR A 177
 None
 1.24A 1yq7A-3p8lA:
24.9		 1yq7A-3p8lA:
27.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YQ7_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 11 LEU A  79
ASP A  88
ARG A  93
GLN A 153
THR A 177
 None
 0.69A 1yq7A-3p8lA:
24.9		 1yq7A-3p8lA:
27.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YV5_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 10 ASP A  82
ASP A  88
ARG A  93
LYS A 176
THR A 177
 None
 1.28A 1yv5A-3p8lA:
24.9		 1yv5A-3p8lA:
27.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YV5_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		6 / 10 LEU A  79
ASP A  82
ASP A  88
ARG A  93
GLN A 153
THR A 177
 None
 1.10A 1yv5A-3p8lA:
24.9		 1yv5A-3p8lA:
27.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_B_FLPB2701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 12 LEU A 135
LEU A 123
ILE A 186
GLY A 189
ALA A 187
 None
 1.08A 2aylB-3p8lA:
undetectable		 2aylB-3p8lA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 11 LEU A  79
ASP A  82
ARG A  93
GLN A 153
THR A 177
 None
 1.20A 2f8cF-3p8lA:
25.7		 2f8cF-3p8lA:
26.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 11 LEU A  79
ASP A  88
ARG A  93
GLN A 153
THR A 177
 None
 0.78A 2f8cF-3p8lA:
25.7		 2f8cF-3p8lA:
26.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 10 LEU A  79
ASP A  82
ARG A  93
GLN A 153
THR A 177
 None
 1.18A 2f8zF-3p8lA:
25.6		 2f8zF-3p8lA:
26.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 10 LEU A  79
ASP A  88
ARG A  93
GLN A 153
THR A 177
 None
 0.74A 2f8zF-3p8lA:
25.6		 2f8zF-3p8lA:
26.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F94_F_BFQF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 12 LEU A  79
ASP A  82
ARG A  93
GLN A 153
THR A 177
 None
 1.02A 2f94F-3p8lA:
25.6		 2f94F-3p8lA:
26.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F94_F_BFQF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 12 LEU A  79
ASP A  88
ARG A  93
GLN A 153
THR A 177
 None
 0.49A 2f94F-3p8lA:
25.6		 2f94F-3p8lA:
26.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F94_F_BFQF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 12 LEU A  79
ASP A  88
GLN A 153
THR A 177
GLN A 214
 None
 0.91A 2f94F-3p8lA:
25.6		 2f94F-3p8lA:
26.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9K_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 10 LEU A  79
ASP A  88
ARG A  93
GLN A 153
THR A 177
 None
 0.82A 2f9kF-3p8lA:
25.6		 2f9kF-3p8lA:
26.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_A_RISA400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 9 LEU A  79
ASP A  82
ASP A  88
GLN A 153
LYS A 176
 None
 1.46A 2o1oA-3p8lA:
24.1		 2o1oA-3p8lA:
25.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_A_RISA400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 9 LEU A  79
ASP A  82
ASP A  88
LYS A 176
THR A 177
 None
 1.36A 2o1oA-3p8lA:
24.1		 2o1oA-3p8lA:
25.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_A_RISA400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 9 LEU A  79
ASP A  88
ARG A  93
GLN A 153
LYS A 176
 None
 1.09A 2o1oA-3p8lA:
24.1		 2o1oA-3p8lA:
25.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_A_RISA400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 9 LEU A  79
ASP A  88
ARG A  93
LYS A 176
THR A 177
 None
 1.00A 2o1oA-3p8lA:
24.1		 2o1oA-3p8lA:
25.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_B_RISB400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 10 LEU A  79
ASP A  82
ASP A  88
ARG A  93
GLN A 153
 None
 1.24A 2o1oB-3p8lA:
25.2		 2o1oB-3p8lA:
25.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_B_RISB400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 10 LEU A  79
ASP A  82
ASP A  88
ARG A  93
THR A 177
 None
 1.16A 2o1oB-3p8lA:
25.2		 2o1oB-3p8lA:
25.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		3 / 3 VAL A 275
LYS A 272
HIS A  -1
 None
 0.88A 3elzA-3p8lA:
undetectable		 3elzA-3p8lA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECNB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 9 LEU A  79
THR A  76
GLY A 114
ALA A 111
THR A 107
 None
 1.44A 3jusB-3p8lA:
undetectable		 3jusB-3p8lA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 11 LEU A  79
ASP A  82
ARG A  93
GLN A 153
THR A 177
 None
 1.25A 3n45F-3p8lA:
25.6		 3n45F-3p8lA:
26.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 11 LEU A  79
ASP A  88
ARG A  93
GLN A 153
THR A 177
 None
 0.82A 3n45F-3p8lA:
25.6		 3n45F-3p8lA:
26.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N46_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 10 LEU A  79
ASP A  82
ASP A  88
GLN A 153
THR A 177
 None
 1.18A 3n46F-3p8lA:
25.7		 3n46F-3p8lA:
26.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N46_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 10 LEU A  79
ASP A  88
ARG A  93
GLN A 153
THR A 177
 None
 0.83A 3n46F-3p8lA:
25.7		 3n46F-3p8lA:
26.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 12 LEU A 135
LEU A 123
ILE A 186
GLY A 189
ALA A 187
 None
 1.11A 3n8xB-3p8lA:
undetectable		 3n8xB-3p8lA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_1
(16S RRNA METHYLASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		4 / 5 ASN A  99
ASP A  90
GLU A 160
SER A  36
 None
 1.21A 3p2kC-3p8lA:
undetectable		 3p2kC-3p8lA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		4 / 8 THR A 177
GLY A 152
GLN A 153
VAL A 172
 None
 0.94A 4e1vG-3p8lA:
undetectable		 4e1vG-3p8lA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_D_NCTD501_1
(CYTOCHROME P450 2A6)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		4 / 7 GLY A 189
ILE A 271
LEU A 283
PHE A 278
 None
 0.90A 4ejjD-3p8lA:
undetectable		 4ejjD-3p8lA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ5_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 10 LEU A  79
ASP A  88
ARG A  93
GLN A 153
THR A 177
 None
 0.78A 4kq5A-3p8lA:
25.1		 4kq5A-3p8lA:
27.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQS_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 10 LEU A  79
ASP A  82
ARG A  93
GLN A 153
THR A 177
 None
 1.21A 4kqsA-3p8lA:
25.3		 4kqsA-3p8lA:
27.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQS_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 10 LEU A  79
ASP A  88
ARG A  93
GLN A 153
THR A 177
 None
 0.75A 4kqsA-3p8lA:
25.3		 4kqsA-3p8lA:
27.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NG6_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 12 LEU A  79
ASP A  82
ARG A  93
GLN A 153
THR A 177
 None
 1.02A 4ng6A-3p8lA:
25.0		 4ng6A-3p8lA:
27.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NG6_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 12 LEU A  79
ASP A  88
ARG A  93
GLN A 153
THR A 177
 None
 0.47A 4ng6A-3p8lA:
25.0		 4ng6A-3p8lA:
27.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NG6_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 12 LEU A  79
ASP A  88
GLN A 153
THR A 177
GLN A 214
 None
 0.95A 4ng6A-3p8lA:
25.0		 4ng6A-3p8lA:
27.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKE_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 10 LEU A  79
ASP A  82
ARG A  93
GLN A 153
THR A 177
 None
 1.18A 4nkeA-3p8lA:
25.0		 4nkeA-3p8lA:
26.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKE_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 10 LEU A  79
ASP A  88
ARG A  93
GLN A 153
THR A 177
 None
 0.74A 4nkeA-3p8lA:
25.0		 4nkeA-3p8lA:
26.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGU_A_210A405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 9 LEU A  79
ASP A  82
ASP A  88
ARG A  93
THR A 177
 None
 1.04A 4oguA-3p8lA:
25.3		 4oguA-3p8lA:
26.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0W_A_ZOLA501_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 11 LEU A  79
ASP A  88
ARG A  93
GLN A 153
THR A 177
 None
 0.77A 4p0wA-3p8lA:
25.5		 4p0wA-3p8lA:
26.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 10 LEU A  79
ASP A  82
ARG A  93
GLN A 153
THR A 177
 None
 1.23A 4rxdA-3p8lA:
24.4		 4rxdA-3p8lA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 10 LEU A  79
ASP A  88
ARG A  93
GLN A 153
THR A 177
 None
 0.75A 4rxdA-3p8lA:
24.4		 4rxdA-3p8lA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 10 LEU A  79
ASP A  82
ARG A  93
GLN A 153
THR A 177
 None
 1.21A 4rxdB-3p8lA:
24.7		 4rxdB-3p8lA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 10 LEU A  79
ASP A  88
ARG A  93
GLN A 153
THR A 177
 None
 0.74A 4rxdB-3p8lA:
24.7		 4rxdB-3p8lA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 10 LEU A  79
ASP A  82
ARG A  93
GLN A 153
THR A 177
 None
 1.22A 4rxdC-3p8lA:
24.8		 4rxdC-3p8lA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 10 LEU A  79
ASP A  88
ARG A  93
GLN A 153
THR A 177
 None
 0.74A 4rxdC-3p8lA:
24.8		 4rxdC-3p8lA:
25.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		6 / 8 SER A  78
LEU A  79
ASP A  88
ARG A  93
MET A 149
GLN A 153
 None
 0.33A 4umjA-3p8lA:
35.3		 4umjA-3p8lA:
44.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		6 / 9 LEU A  79
ASP A  82
ASP A  88
ARG A  93
GLN A 153
THR A 177
 None
 0.97A 4umjB-3p8lA:
35.9		 4umjB-3p8lA:
44.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		7 / 9 SER A  78
LEU A  79
ASP A  88
ARG A  93
MET A 149
GLN A 153
THR A 177
 None
 0.44A 4umjB-3p8lA:
35.9		 4umjB-3p8lA:
44.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_ACTA605_0
(SERUM ALBUMIN)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		4 / 6 HIS A  75
GLY A  41
GLU A  72
ARG A  43
 None
 1.16A 4zbqA-3p8lA:
2.1		 4zbqA-3p8lA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		4 / 7 ILE A 199
LEU A 202
GLY A 188
GLY A 189
 None
 0.65A 5a06A-3p8lA:
undetectable		 5a06A-3p8lA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		4 / 7 ILE A 199
LEU A 202
GLY A 188
GLY A 189
 None
 0.66A 5a06B-3p8lA:
undetectable		 5a06B-3p8lA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		4 / 7 ILE A 199
LEU A 202
GLY A 188
GLY A 189
 None
 0.66A 5a06C-3p8lA:
undetectable		 5a06C-3p8lA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		4 / 7 ILE A 199
LEU A 202
GLY A 188
GLY A 189
 None
 0.65A 5a06E-3p8lA:
undetectable		 5a06E-3p8lA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		4 / 7 ILE A 199
LEU A 202
GLY A 188
GLY A 189
 None
 0.67A 5a06F-3p8lA:
undetectable		 5a06F-3p8lA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG5_A_RISA400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 12 LEU A  79
ASP A  82
ARG A  93
GLN A 153
THR A 177
 None
 1.21A 5cg5A-3p8lA:
25.0		 5cg5A-3p8lA:
26.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG5_A_RISA400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 12 LEU A  79
ASP A  88
ARG A  93
GLN A 153
THR A 177
 None
 0.73A 5cg5A-3p8lA:
25.0		 5cg5A-3p8lA:
26.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG6_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 12 LEU A  79
ASP A  82
ARG A  93
GLN A 153
THR A 177
 None
 1.20A 5cg6A-3p8lA:
25.5		 5cg6A-3p8lA:
26.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG6_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 12 LEU A  79
ASP A  88
ARG A  93
GLN A 153
THR A 177
 None
 0.73A 5cg6A-3p8lA:
25.5		 5cg6A-3p8lA:
26.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		3 / 3 ASP A 217
LEU A  79
ARG A  93
 None
 0.47A 5e8qA-3p8lA:
undetectable		 5e8qA-3p8lA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 11 THR A 203
ALA A 206
GLY A 189
GLY A 188
ALA A 187
 None
 1.02A 5lf3K-3p8lA:
undetectable
5lf3L-3p8lA:
undetectable		 5lf3K-3p8lA:
21.50
5lf3L-3p8lA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		5 / 11 THR A 203
ALA A 206
GLY A 189
GLY A 188
ALA A 187
 None
 1.03A 5lf3Y-3p8lA:
undetectable
5lf3Z-3p8lA:
undetectable		 5lf3Y-3p8lA:
21.50
5lf3Z-3p8lA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_D_ZOLD401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		4 / 7 LEU A  79
ASP A  88
ARG A  93
GLN A 153
 None
 0.48A 6g31D-3p8lA:
21.9		 6g31D-3p8lA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_J_ZOLJ401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		4 / 6 LEU A  79
ASP A  82
ARG A  93
GLN A 153
 None
 1.27A 6g31J-3p8lA:
22.7		 6g31J-3p8lA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_J_ZOLJ401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3p8l GERANYLTRANSTRANSFER
ASE
(Enterococcus
faecalis) 		4 / 6 LEU A  79
ASP A  88
ARG A  93
GLN A 153
 None
 0.67A 6g31J-3p8lA:
22.7		 6g31J-3p8lA:
13.58