SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3p8s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E71_M_ASCM995_0
(MYROSINASE MA1)		 3p8s JACALIN
(Artocarpus
heterophyllus) 		4 / 7 ILE A  89
PHE A 140
PHE A 151
PHE A 128
 None
 1.09A 1e71M-3p8sA:
undetectable		 1e71M-3p8sA:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)		 3p8s JACALIN
(Artocarpus
heterophyllus) 		4 / 7 ILE A  89
PHE A 140
PHE A 151
PHE A 128
 None
 1.10A 1e72M-3p8sA:
undetectable		 1e72M-3p8sA:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQW_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN)		 3p8s JACALIN
(Artocarpus
heterophyllus) 		5 / 12 PHE A 110
ILE A  49
LEU A  52
LEU A  82
ILE A  80
 None
 1.21A 1kqwA-3p8sA:
undetectable		 1kqwA-3p8sA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3p8s JACALIN
(Artocarpus
heterophyllus) 		5 / 10 THR A 116
PHE A 110
VAL A 105
PHE A 151
VAL A  92
 None
 1.50A 1q23E-3p8sA:
undetectable		 1q23E-3p8sA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_A_SAMA301_1
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 3p8s JACALIN
(Artocarpus
heterophyllus) 		3 / 3 GLY A  50
ASP A  51
ASN A  44
 None
 0.59A 1vq1A-3p8sA:
undetectable		 1vq1A-3p8sA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_2
(POL POLYPROTEIN)		 3p8s JACALIN
(Artocarpus
heterophyllus) 		5 / 9 GLY A  31
ALA A  32
GLY A  35
ILE A  36
LEU A 155
 None
 0.97A 3u7sB-3p8sA:
undetectable		 3u7sB-3p8sA:
25.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3p8s JACALIN
(Artocarpus
heterophyllus) 		4 / 8 PHE A 128
TYR A  95
VAL A 105
ILE A  49
 None
 1.08A 4a97C-3p8sA:
undetectable		 4a97C-3p8sA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3p8s JACALIN
(Artocarpus
heterophyllus) 		4 / 8 PHE A 128
TYR A  95
VAL A 105
ILE A  49
 None
 1.04A 4a97G-3p8sA:
undetectable		 4a97G-3p8sA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3p8s JACALIN
(Artocarpus
heterophyllus) 		4 / 8 ASN A 129
PHE A 128
THR A 116
GLY A 118
 None
 0.99A 5nzxA-3p8sA:
undetectable		 5nzxA-3p8sA:
19.47