SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3p94'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_2
(ESTROGEN RECEPTOR)		 3p94 GDSL-LIKE LIPASE
(Parabacteroides
distasonis) 		4 / 6 LEU A 104
LEU A 126
LEU A 195
LEU A 199
 None
 0.69A 1errA-3p94A:
undetectable		 1errA-3p94A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)		 3p94 GDSL-LIKE LIPASE
(Parabacteroides
distasonis) 		4 / 7 GLY A  52
GLN A  80
ARG A  88
ILE A 103
 None
 1.01A 1rxcD-3p94A:
4.7		 1rxcD-3p94A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 3p94 GDSL-LIKE LIPASE
(Parabacteroides
distasonis) 		4 / 7 GLY A  52
GLN A  80
ARG A  88
ILE A 103
 None
 1.08A 1rxcF-3p94A:
4.7		 1rxcF-3p94A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 3p94 GDSL-LIKE LIPASE
(Parabacteroides
distasonis) 		4 / 7 GLY A  52
GLN A  80
ARG A  88
ILE A 103
 None
 1.07A 1rxcL-3p94A:
3.0		 1rxcL-3p94A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AJV_L_COCL501_1
(ANTIBODY 7A1 FAB')		 3p94 GDSL-LIKE LIPASE
(Parabacteroides
distasonis) 		4 / 7 ALA A  62
TYR A 211
TYR A  35
PHE A  67
 None
 1.21A 2ajvH-3p94A:
undetectable
2ajvL-3p94A:
undetectable		 2ajvH-3p94A:
20.34
2ajvL-3p94A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_A_LEUA1894_0
(AMINOACYL-TRNA
SYNTHETASE)		 3p94 GDSL-LIKE LIPASE
(Parabacteroides
distasonis) 		4 / 8 TYR A 181
ASP A 183
SER A 186
HIS A 185
 None
 1.28A 2bteA-3p94A:
undetectable		 2bteA-3p94A:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G78_A_REAA200_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 3p94 GDSL-LIKE LIPASE
(Parabacteroides
distasonis) 		5 / 12 PHE A 142
ILE A 138
THR A  82
VAL A 127
LEU A 166
 None
 1.00A 2g78A-3p94A:
undetectable		 2g78A-3p94A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)		 3p94 GDSL-LIKE LIPASE
(Parabacteroides
distasonis) 		4 / 6 GLY A  52
GLN A  80
ARG A  88
ILE A 103
 None
 1.03A 3kvvA-3p94A:
3.3		 3kvvA-3p94A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 3p94 GDSL-LIKE LIPASE
(Parabacteroides
distasonis) 		4 / 6 GLY A  52
GLN A  80
ARG A  88
ILE A 103
 None
 1.05A 3kvvB-3p94A:
undetectable		 3kvvB-3p94A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 3p94 GDSL-LIKE LIPASE
(Parabacteroides
distasonis) 		4 / 6 GLY A  52
GLN A  80
ARG A  88
ILE A 103
 None
 1.01A 3kvvC-3p94A:
3.1		 3kvvC-3p94A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_D_URFD254_1
(URIDINE
PHOSPHORYLASE)		 3p94 GDSL-LIKE LIPASE
(Parabacteroides
distasonis) 		4 / 6 GLY A  52
GLN A  80
ARG A  88
ILE A 103
 None
 1.03A 3kvvD-3p94A:
3.1		 3kvvD-3p94A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 3p94 GDSL-LIKE LIPASE
(Parabacteroides
distasonis) 		4 / 6 GLY A  52
GLN A  80
ARG A  88
ILE A 103
 None
 1.05A 3kvvE-3p94A:
3.5		 3kvvE-3p94A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 3p94 GDSL-LIKE LIPASE
(Parabacteroides
distasonis) 		4 / 6 GLY A  52
GLN A  80
ARG A  88
ILE A 103
 None
 1.08A 3kvvF-3p94A:
4.4		 3kvvF-3p94A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 3p94 GDSL-LIKE LIPASE
(Parabacteroides
distasonis) 		4 / 6 VAL A 127
VAL A 140
PHE A  89
GLU A 131
 None
 1.49A 3n61A-3p94A:
0.9
3n61B-3p94A:
undetectable		 3n61A-3p94A:
17.37
3n61B-3p94A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ARC_A_LEUA1001_0
(LEUCINE--TRNA LIGASE)		 3p94 GDSL-LIKE LIPASE
(Parabacteroides
distasonis) 		4 / 7 TYR A 181
ASP A 183
SER A 186
HIS A 185
 None
 1.28A 4arcA-3p94A:
undetectable		 4arcA-3p94A:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)		 3p94 GDSL-LIKE LIPASE
(Parabacteroides
distasonis) 		4 / 6 GLY A  52
GLN A  80
ARG A  88
ILE A 103
 None
 1.06A 4e1vF-3p94A:
2.6		 4e1vF-3p94A:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3p94 GDSL-LIKE LIPASE
(Parabacteroides
distasonis) 		4 / 6 ILE A 222
VAL A  73
PHE A  66
THR A  56
 None
 1.03A 4xe5A-3p94A:
undetectable		 4xe5A-3p94A:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_B_PAUB601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3p94 GDSL-LIKE LIPASE
(Parabacteroides
distasonis) 		4 / 7 ALA A 105
GLU A  84
ARG A  88
GLY A  76
 None
 0.85A 5e26A-3p94A:
undetectable
5e26B-3p94A:
undetectable		 5e26A-3p94A:
19.51
5e26B-3p94A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3p94 GDSL-LIKE LIPASE
(Parabacteroides
distasonis) 		4 / 7 GLU A  84
ARG A  88
GLY A  76
ALA A 105
 None
 0.85A 5e26C-3p94A:
undetectable
5e26D-3p94A:
undetectable		 5e26C-3p94A:
19.51
5e26D-3p94A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 3p94 GDSL-LIKE LIPASE
(Parabacteroides
distasonis) 		5 / 12 ILE A 103
VAL A 102
GLY A  52
PHE A  50
LEU A  96
 None
 0.98A 5ergB-3p94A:
undetectable		 5ergB-3p94A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_B_NOVB403_1
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 3p94 GDSL-LIKE LIPASE
(Parabacteroides
distasonis) 		4 / 7 PHE A  89
ARG A  88
ARG A  75
ALA A 133
 None
 1.28A 6b89A-3p94A:
undetectable		 6b89A-3p94A:
15.90