SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3p9t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_2
(PROTEIN (PROTEASE))		 3p9t REPRESSOR
(Stenotrophomonas
maltophilia) 		5 / 12 ALA A  19
ASP A  18
ILE A  62
THR A  33
ILE A  37
 None
 0.98A 1c6zB-3p9tA:
undetectable		 1c6zB-3p9tA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4477_1
(NEURAMINIDASE)		 3p9t REPRESSOR
(Stenotrophomonas
maltophilia) 		5 / 12 ARG A  13
ALA A  61
GLU A  14
ARG A  65
ARG A 105
 None
 1.37A 2cmlD-3p9tA:
undetectable		 2cmlD-3p9tA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_2
(ANDROGEN RECEPTOR)		 3p9t REPRESSOR
(Stenotrophomonas
maltophilia) 		4 / 6 LEU A  74
MET A 110
MET A 113
LEU A 174
 None
TCL  A 221 ( 3.4A)
TCL  A 222 ( 4.7A)
None
 1.38A 2oz7A-3p9tA:
undetectable		 2oz7A-3p9tA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_B_BCZB468_0
(NEURAMINIDASE)		 3p9t REPRESSOR
(Stenotrophomonas
maltophilia) 		5 / 12 ARG A  13
ALA A  61
GLU A  14
ARG A  65
ARG A 105
 None
 1.30A 3k37B-3p9tA:
undetectable		 3k37B-3p9tA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_A_SAMA220_0
(16S RRNA METHYLASE)		 3p9t REPRESSOR
(Stenotrophomonas
maltophilia) 		5 / 12 GLY A 210
PRO A 213
VAL A 212
ALA A  91
LEU A 194
 None
 1.27A 3mteA-3p9tA:
undetectable		 3mteA-3p9tA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPN_A_ZMRA700_1
(NEURAMINIDASE)		 3p9t REPRESSOR
(Stenotrophomonas
maltophilia) 		5 / 12 ARG A  13
ALA A  61
GLU A  14
ARG A  65
ARG A 105
 None
 1.24A 4cpnA-3p9tA:
undetectable		 4cpnA-3p9tA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3p9t REPRESSOR
(Stenotrophomonas
maltophilia) 		5 / 10 ALA A  39
ILE A  37
ALA A  11
ALA A  47
ILE A  16
 None
 1.07A 4lbgA-3p9tA:
undetectable		 4lbgA-3p9tA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3p9t REPRESSOR
(Stenotrophomonas
maltophilia) 		5 / 9 ALA A  39
ILE A  37
ALA A  11
ALA A  47
ILE A  16
 None
 1.08A 4lbgB-3p9tA:
undetectable		 4lbgB-3p9tA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_1
(NS3 PROTEASE)		 3p9t REPRESSOR
(Stenotrophomonas
maltophilia) 		5 / 9 VAL A 206
GLY A 205
ILE A  94
LEU A 194
ASP A  88
 None
 1.40A 6c2mC-3p9tA:
undetectable		 6c2mC-3p9tA:
17.84