SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3p9x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4002_1
(SERUM ALBUMIN)		 3p9x PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Bacillus
halodurans) 		4 / 4 ARG A 176
ALA A 180
ALA A 151
GLU A 153
 SO4  A 214 (-4.4A)
None
None
None
 0.92A 1e7bA-3p9xA:
undetectable		 1e7bA-3p9xA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4002_1
(SERUM ALBUMIN)		 3p9x PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Bacillus
halodurans) 		4 / 4 ARG A 176
ALA A 180
ALA A 151
GLU A 153
 SO4  A 214 (-4.4A)
None
None
None
 0.90A 1e7bB-3p9xA:
undetectable		 1e7bB-3p9xA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4002_1
(SERUM ALBUMIN)		 3p9x PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Bacillus
halodurans) 		4 / 5 ARG A 176
ALA A 180
ALA A 151
GLU A 153
 SO4  A 214 (-4.4A)
None
None
None
 0.99A 1e7cA-3p9xA:
undetectable		 1e7cA-3p9xA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_0
(VP39)		 3p9x PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Bacillus
halodurans) 		5 / 12 ILE A 108
PRO A 117
GLY A 118
VAL A 135
LEU A 177
 None
 1.08A 1vptA-3p9xA:
3.4		 1vptA-3p9xA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_2
(PROTEASE RETROPEPSIN)		 3p9x PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Bacillus
halodurans) 		6 / 12 LEU A  34
GLY A  88
ALA A  87
ILE A  18
ILE A 105
ILE A   6
 None
 1.33A 2rkfB-3p9xA:
undetectable		 2rkfB-3p9xA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_1
(PROTEASE RETROPEPSIN)		 3p9x PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Bacillus
halodurans) 		6 / 12 LEU A  34
GLY A  88
ALA A  87
ILE A  18
ILE A 105
ILE A   6
 None
 1.34A 2rkgA-3p9xA:
undetectable		 2rkgA-3p9xA:
20.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCJ_B_THHB401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 3p9x PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Bacillus
halodurans) 		4 / 8 LEU A  98
ASN A 107
VAL A 140
GLY A 143
 None
 0.64A 3dcjB-3p9xA:
26.5		 3dcjB-3p9xA:
33.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_A_MIXA1301_1
(DNA TOPOISOMERASE
2-BETA)		 3p9x PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Bacillus
halodurans) 		4 / 7 ILE A 108
ASN A  14
GLU A 174
GLN A 124
 None
SO4  A 211 (-4.0A)
None
None
 1.12A 4g0vA-3p9xA:
2.7		 4g0vA-3p9xA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3p9x PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Bacillus
halodurans) 		5 / 10 GLU A  16
VAL A  31
ALA A   8
ALA A  87
ILE A   6
 None
 1.01A 4lbgA-3p9xA:
4.6		 4lbgA-3p9xA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3p9x PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Bacillus
halodurans) 		5 / 9 GLU A  16
VAL A  31
ALA A   8
ALA A  87
ILE A   6
 None
 1.06A 4lbgB-3p9xA:
4.6		 4lbgB-3p9xA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_2
(PROTEASE)		 3p9x PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Bacillus
halodurans) 		6 / 12 LEU A  34
GLY A  88
ALA A  87
ILE A  18
ILE A 105
ILE A   6
 None
 1.31A 5e5jB-3p9xA:
undetectable		 5e5jB-3p9xA:
18.59