SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pao'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_A_DCFA353_1
(ADENOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		7 / 12 HIS A  16
HIS A  18
ASP A 100
PHE A  59
GLU A 199
HIS A 220
ASP A 277
 ZN  A 327 (-3.4A)
ADE  A 328 ( 3.0A)
None
None
ADE  A 328 (-3.0A)
ADE  A 328 ( 4.2A)
ZN  A 327 ( 2.6A)
 1.28A 1a4lA-3paoA:
39.5		 1a4lA-3paoA:
30.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_A_DCFA353_1
(ADENOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		8 / 12 HIS A  16
HIS A  18
PHE A  59
HIS A 196
GLU A 199
HIS A 220
ASP A 277
ASP A 278
 ZN  A 327 (-3.4A)
ADE  A 328 ( 3.0A)
None
ZN  A 327 ( 3.5A)
ADE  A 328 (-3.0A)
ADE  A 328 ( 4.2A)
ZN  A 327 ( 2.6A)
ADE  A 328 (-2.8A)
 0.53A 1a4lA-3paoA:
39.5		 1a4lA-3paoA:
30.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_A_DCFA353_1
(ADENOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  16
PHE A 282
PHE A  59
HIS A 220
ASP A 278
 ZN  A 327 (-3.4A)
None
None
ADE  A 328 ( 4.2A)
ADE  A 328 (-2.8A)
 1.11A 1a4lA-3paoA:
39.5		 1a4lA-3paoA:
30.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_B_DCFB853_1
(ADENOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		7 / 12 HIS A  18
ASP A 100
PHE A  59
LEU A  60
GLU A 199
HIS A 220
ASP A 277
 ADE  A 328 ( 3.0A)
None
None
ADE  A 328 (-4.9A)
ADE  A 328 (-3.0A)
ADE  A 328 ( 4.2A)
ZN  A 327 ( 2.6A)
 1.32A 1a4lB-3paoA:
39.4		 1a4lB-3paoA:
30.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_B_DCFB853_1
(ADENOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  18
LEU A  56
HIS A 196
ASP A 277
ASP A 278
 ADE  A 328 ( 3.0A)
ADE  A 328 (-4.6A)
ZN  A 327 ( 3.5A)
ZN  A 327 ( 2.6A)
ADE  A 328 (-2.8A)
 1.01A 1a4lB-3paoA:
39.4		 1a4lB-3paoA:
30.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_B_DCFB853_1
(ADENOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  18
LEU A  56
PHE A  59
HIS A 196
ASP A 278
 ADE  A 328 ( 3.0A)
ADE  A 328 (-4.6A)
None
ZN  A 327 ( 3.5A)
ADE  A 328 (-2.8A)
 1.21A 1a4lB-3paoA:
39.4		 1a4lB-3paoA:
30.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_B_DCFB853_1
(ADENOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		8 / 12 HIS A  18
PHE A  59
LEU A  60
HIS A 196
GLU A 199
HIS A 220
ASP A 277
ASP A 278
 ADE  A 328 ( 3.0A)
None
ADE  A 328 (-4.9A)
ZN  A 327 ( 3.5A)
ADE  A 328 (-3.0A)
ADE  A 328 ( 4.2A)
ZN  A 327 ( 2.6A)
ADE  A 328 (-2.8A)
 0.56A 1a4lB-3paoA:
39.4		 1a4lB-3paoA:
30.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_B_DCFB853_1
(ADENOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 PHE A  59
LEU A  60
HIS A 196
ASP A 277
ASP A 278
 None
ADE  A 328 (-4.9A)
ZN  A 327 ( 3.5A)
ZN  A 327 ( 2.6A)
ADE  A 328 (-2.8A)
 1.35A 1a4lB-3paoA:
39.4		 1a4lB-3paoA:
30.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		7 / 12 HIS A  16
HIS A  18
ASP A 100
PHE A  59
GLU A 199
HIS A 220
ASP A 277
 ZN  A 327 (-3.4A)
ADE  A 328 ( 3.0A)
None
None
ADE  A 328 (-3.0A)
ADE  A 328 ( 4.2A)
ZN  A 327 ( 2.6A)
 1.31A 1a4lC-3paoA:
39.5		 1a4lC-3paoA:
30.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		8 / 12 HIS A  16
HIS A  18
PHE A  59
HIS A 196
GLU A 199
HIS A 220
ASP A 277
ASP A 278
 ZN  A 327 (-3.4A)
ADE  A 328 ( 3.0A)
None
ZN  A 327 ( 3.5A)
ADE  A 328 (-3.0A)
ADE  A 328 ( 4.2A)
ZN  A 327 ( 2.6A)
ADE  A 328 (-2.8A)
 0.54A 1a4lC-3paoA:
39.5		 1a4lC-3paoA:
30.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  16
PHE A 282
PHE A  59
HIS A 220
ASP A 278
 ZN  A 327 (-3.4A)
None
None
ADE  A 328 ( 4.2A)
ADE  A 328 (-2.8A)
 1.05A 1a4lC-3paoA:
39.5		 1a4lC-3paoA:
30.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 196
HIS A 220
PHE A 282
HIS A  16
HIS A  18
 ZN  A 327 ( 3.5A)
ADE  A 328 ( 4.2A)
None
ZN  A 327 (-3.4A)
ADE  A 328 ( 3.0A)
 1.22A 1a4lC-3paoA:
39.5		 1a4lC-3paoA:
30.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_D_DCFD1853_1
(ADENOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		6 / 12 HIS A  18
ASP A 100
PHE A  59
GLU A 199
HIS A 220
ASP A 277
 ADE  A 328 ( 3.0A)
None
None
ADE  A 328 (-3.0A)
ADE  A 328 ( 4.2A)
ZN  A 327 ( 2.6A)
 1.34A 1a4lD-3paoA:
39.6		 1a4lD-3paoA:
30.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_D_DCFD1853_1
(ADENOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		7 / 12 HIS A  18
PHE A  59
HIS A 196
GLU A 199
HIS A 220
ASP A 277
ASP A 278
 ADE  A 328 ( 3.0A)
None
ZN  A 327 ( 3.5A)
ADE  A 328 (-3.0A)
ADE  A 328 ( 4.2A)
ZN  A 327 ( 2.6A)
ADE  A 328 (-2.8A)
 0.52A 1a4lD-3paoA:
39.6		 1a4lD-3paoA:
30.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_D_DCFD1853_1
(ADENOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  18
PHE A 282
PHE A  59
HIS A 196
ASP A 278
 ADE  A 328 ( 3.0A)
None
None
ZN  A 327 ( 3.5A)
ADE  A 328 (-2.8A)
 1.41A 1a4lD-3paoA:
39.6		 1a4lD-3paoA:
30.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		4 / 8 HIS A 196
HIS A  16
HIS A 220
HIS A  18
 ZN  A 327 ( 3.5A)
ZN  A 327 (-3.4A)
ADE  A 328 ( 4.2A)
ADE  A 328 ( 3.0A)
 1.01A 1bzmA-3paoA:
undetectable		 1bzmA-3paoA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C3S_A_SHHA952_1
(HDLP (HISTONE
DEACETYLASE-LIKE
PROTEIN))		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 11 HIS A  16
HIS A 196
ASP A 277
ASP A 278
TYR A  63
 ZN  A 327 (-3.4A)
ZN  A 327 ( 3.5A)
ZN  A 327 ( 2.6A)
ADE  A 328 (-2.8A)
ADE  A 328 (-4.0A)
 1.34A 1c3sA-3paoA:
undetectable		 1c3sA-3paoA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_A_PPFA410_1
(PHOSPHONOACETATE
HYDROLASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		4 / 5 ASP A 277
HIS A  18
HIS A 220
HIS A 196
 ZN  A 327 ( 2.6A)
ADE  A 328 ( 3.0A)
ADE  A 328 ( 4.2A)
ZN  A 327 ( 3.5A)
 1.07A 1ei6A-3paoA:
undetectable		 1ei6A-3paoA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T69_A_SHHA379_1
(HISTONE DEACETYLASE
8)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  16
HIS A 196
ASP A 277
ASP A 278
TYR A  63
 ZN  A 327 (-3.4A)
ZN  A 327 ( 3.5A)
ZN  A 327 ( 2.6A)
ADE  A 328 (-2.8A)
ADE  A 328 (-4.0A)
 1.28A 1t69A-3paoA:
undetectable		 1t69A-3paoA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_A_SHHA2452_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 11 LEU A 140
HIS A  18
ASP A 278
GLY A  21
TYR A  63
 None
ADE  A 328 ( 3.0A)
ADE  A 328 (-2.8A)
None
ADE  A 328 (-4.0A)
 1.21A 1zz1A-3paoA:
undetectable		 1zz1A-3paoA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC2_0
(N8-ACTINOMYCIN D)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		3 / 3 THR A 103
PRO A 101
THR A 105
 None
 0.76A 209dC-3paoA:
undetectable		 209dC-3paoA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_D_H4BD1006_1
(HYPOTHETICAL PROTEIN
PH0634)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 10 HIS A 196
HIS A  16
HIS A 220
GLU A 199
TYR A  63
 ZN  A 327 ( 3.5A)
ZN  A 327 (-3.4A)
ADE  A 328 ( 4.2A)
ADE  A 328 (-3.0A)
ADE  A 328 (-4.0A)
 1.29A 2dttD-3paoA:
undetectable
2dttF-3paoA:
undetectable		 2dttD-3paoA:
15.79
2dttF-3paoA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_A_SCKA901_1
(ACETYLCHOLINESTERASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		4 / 8 TYR A  63
ASP A 100
TYR A  64
HIS A 174
 ADE  A 328 (-4.0A)
None
None
None
 1.47A 2ha2A-3paoA:
undetectable		 2ha2A-3paoA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		3 / 3 THR A  22
ASP A 168
SER A 170
 None
ADE  A 328 ( 4.2A)
None
 0.62A 2nxeA-3paoA:
undetectable		 2nxeA-3paoA:
24.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		3 / 3 THR A  22
ASP A 168
SER A 170
 None
ADE  A 328 ( 4.2A)
None
 0.68A 2nxeB-3paoA:
undetectable		 2nxeB-3paoA:
24.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		4 / 6 LEU A 251
HIS A  16
HIS A  18
HIS A 196
 None
ZN  A 327 (-3.4A)
ADE  A 328 ( 3.0A)
ZN  A 327 ( 3.5A)
 0.85A 2ow9A-3paoA:
undetectable		 2ow9A-3paoA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGF_A_ADNA501_1
(ADENOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		6 / 12 HIS A  18
ASP A 100
PHE A  59
HIS A 220
SER A 247
ASP A 277
 ADE  A 328 ( 3.0A)
None
None
ADE  A 328 ( 4.2A)
ADE  A 328 ( 4.5A)
ZN  A 327 ( 2.6A)
 1.24A 2pgfA-3paoA:
39.6		 2pgfA-3paoA:
27.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGF_A_ADNA501_1
(ADENOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		8 / 12 HIS A  18
PHE A  59
HIS A 196
GLU A 199
HIS A 220
SER A 247
ASP A 277
ASP A 278
 ADE  A 328 ( 3.0A)
None
ZN  A 327 ( 3.5A)
ADE  A 328 (-3.0A)
ADE  A 328 ( 4.2A)
ADE  A 328 ( 4.5A)
ZN  A 327 ( 2.6A)
ADE  A 328 (-2.8A)
 0.42A 2pgfA-3paoA:
39.6		 2pgfA-3paoA:
27.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		6 / 12 HIS A  16
HIS A  18
ASP A 100
PHE A  59
HIS A 220
ASP A 277
 ZN  A 327 (-3.4A)
ADE  A 328 ( 3.0A)
None
None
ADE  A 328 ( 4.2A)
ZN  A 327 ( 2.6A)
 1.19A 2pgrA-3paoA:
39.5		 2pgrA-3paoA:
27.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		8 / 12 HIS A  16
HIS A  18
PHE A  59
HIS A 196
GLU A 199
HIS A 220
ASP A 277
ASP A 278
 ZN  A 327 (-3.4A)
ADE  A 328 ( 3.0A)
None
ZN  A 327 ( 3.5A)
ADE  A 328 (-3.0A)
ADE  A 328 ( 4.2A)
ZN  A 327 ( 2.6A)
ADE  A 328 (-2.8A)
 0.54A 2pgrA-3paoA:
39.5		 2pgrA-3paoA:
27.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 196
HIS A 220
PHE A 282
HIS A  16
HIS A  18
 ZN  A 327 ( 3.5A)
ADE  A 328 ( 4.2A)
None
ZN  A 327 (-3.4A)
ADE  A 328 ( 3.0A)
 1.12A 2pgrA-3paoA:
39.5		 2pgrA-3paoA:
27.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_E_GCSE710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		4 / 8 HIS A 196
ILE A 136
HIS A  18
ASP A 168
 ZN  A 327 ( 3.5A)
None
ADE  A 328 ( 3.0A)
ADE  A 328 ( 4.2A)
 1.02A 2xadA-3paoA:
undetectable		 2xadA-3paoA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_F_GCSF710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		4 / 8 HIS A 196
ILE A 136
HIS A  18
ASP A 168
 ZN  A 327 ( 3.5A)
None
ADE  A 328 ( 3.0A)
ADE  A 328 ( 4.2A)
 1.04A 2xadB-3paoA:
undetectable		 2xadB-3paoA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_G_GCSG710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		4 / 8 HIS A 196
ILE A 136
HIS A  18
ASP A 168
 ZN  A 327 ( 3.5A)
None
ADE  A 328 ( 3.0A)
ADE  A 328 ( 4.2A)
 1.03A 2xadC-3paoA:
undetectable		 2xadC-3paoA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_H_GCSH710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		4 / 8 HIS A 196
ILE A 136
HIS A  18
ASP A 168
 ZN  A 327 ( 3.5A)
None
ADE  A 328 ( 3.0A)
ADE  A 328 ( 4.2A)
 1.03A 2xadD-3paoA:
undetectable		 2xadD-3paoA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_C_CHDC1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		4 / 5 PHE A 158
PHE A 162
LEU A 137
PHE A 139
 None
 1.29A 2y69C-3paoA:
undetectable
2y69J-3paoA:
undetectable		 2y69C-3paoA:
20.29
2y69J-3paoA:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_P_CHDP1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		4 / 5 PHE A 158
PHE A 162
LEU A 137
PHE A 139
 None
 1.30A 2y69P-3paoA:
undetectable
2y69W-3paoA:
undetectable		 2y69P-3paoA:
20.29
2y69W-3paoA:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		4 / 6 PHE A 158
PHE A 162
LEU A 137
PHE A 139
 None
 1.18A 3ablP-3paoA:
undetectable
3ablW-3paoA:
undetectable		 3ablP-3paoA:
20.29
3ablW-3paoA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		4 / 5 PHE A 158
PHE A 162
LEU A 137
PHE A 139
 None
 1.32A 3abmC-3paoA:
undetectable
3abmJ-3paoA:
undetectable		 3abmC-3paoA:
20.29
3abmJ-3paoA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		4 / 5 PHE A 158
PHE A 162
LEU A 137
PHE A 139
 None
 1.27A 3abmP-3paoA:
undetectable
3abmW-3paoA:
undetectable		 3abmP-3paoA:
20.29
3abmW-3paoA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		4 / 5 PHE A 158
PHE A 162
LEU A 137
PHE A 139
 None
 1.29A 3ag3C-3paoA:
undetectable
3ag3J-3paoA:
undetectable		 3ag3C-3paoA:
20.29
3ag3J-3paoA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 PHE A  59
PHE A 282
LEU A 251
SER A 138
TYR A  63
 None
None
None
None
ADE  A 328 (-4.0A)
 1.33A 3apvA-3paoA:
undetectable		 3apvA-3paoA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_B_DP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 PHE A  59
PHE A 282
LEU A 251
GLN A  57
TYR A  63
 None
None
None
None
ADE  A 328 (-4.0A)
 1.23A 3apwB-3paoA:
undetectable		 3apwB-3paoA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_A_SHHA301_1
(HISTONE DEACETYLASE
7A)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		4 / 5 HIS A  16
HIS A 196
ASP A 277
ASP A 278
 ZN  A 327 (-3.4A)
ZN  A 327 ( 3.5A)
ZN  A 327 ( 2.6A)
ADE  A 328 (-2.8A)
 1.08A 3c0zA-3paoA:
undetectable		 3c0zA-3paoA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_C_SHHC301_1
(HISTONE DEACETYLASE
7A)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		4 / 6 HIS A  16
HIS A 196
ASP A 277
ASP A 278
 ZN  A 327 (-3.4A)
ZN  A 327 ( 3.5A)
ZN  A 327 ( 2.6A)
ADE  A 328 (-2.8A)
 1.12A 3c0zC-3paoA:
undetectable		 3c0zC-3paoA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		4 / 5 LEU A 251
HIS A  16
HIS A  18
HIS A 196
 None
ZN  A 327 (-3.4A)
ADE  A 328 ( 3.0A)
ZN  A 327 ( 3.5A)
 0.91A 3kecA-3paoA:
undetectable		 3kecA-3paoA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA602_0
(LACCASE-1)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 196
HIS A  16
HIS A  18
 ZN  A 327 ( 3.5A)
ZN  A 327 (-3.4A)
ADE  A 328 ( 3.0A)
 0.60A 3qpkA-3paoA:
undetectable		 3qpkA-3paoA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_D_ADND301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 10 ALA A 224
GLY A 221
LEU A 210
LEU A 234
ILE A 239
 None
 1.12A 3wdmD-3paoA:
undetectable		 3wdmD-3paoA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		4 / 6 LEU A 251
HIS A  16
HIS A  18
HIS A 196
 None
ZN  A 327 (-3.4A)
ADE  A 328 ( 3.0A)
ZN  A 327 ( 3.5A)
 0.88A 4a7bA-3paoA:
undetectable		 4a7bA-3paoA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		8 / 12 LEU A  56
LEU A  60
HIS A 196
GLU A 199
GLU A 171
HIS A 220
SER A 247
ASP A 277
 ADE  A 328 (-4.6A)
ADE  A 328 (-4.9A)
ZN  A 327 ( 3.5A)
ADE  A 328 (-3.0A)
None
ADE  A 328 ( 4.2A)
ADE  A 328 ( 4.5A)
ZN  A 327 ( 2.6A)
 0.81A 4aqlA-3paoA:
5.0		 4aqlA-3paoA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_A_SHHA700_1
(HISTONE DEACETYLASE
8)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 10 HIS A  16
HIS A 196
ASP A 277
ASP A 278
TYR A  63
 ZN  A 327 (-3.4A)
ZN  A 327 ( 3.5A)
ZN  A 327 ( 2.6A)
ADE  A 328 (-2.8A)
ADE  A 328 (-4.0A)
 1.22A 4bz6A-3paoA:
undetectable		 4bz6A-3paoA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_B_SHHB700_1
(HISTONE DEACETYLASE
8)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  16
HIS A 196
ASP A 277
ASP A 278
TYR A  63
 ZN  A 327 (-3.4A)
ZN  A 327 ( 3.5A)
ZN  A 327 ( 2.6A)
ADE  A 328 (-2.8A)
ADE  A 328 (-4.0A)
 1.25A 4bz6A-3paoA:
undetectable
4bz6B-3paoA:
undetectable		 4bz6A-3paoA:
22.62
4bz6B-3paoA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_C_SHHC700_1
(HISTONE DEACETYLASE
8)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  16
HIS A 196
ASP A 277
ASP A 278
TYR A  63
 ZN  A 327 (-3.4A)
ZN  A 327 ( 3.5A)
ZN  A 327 ( 2.6A)
ADE  A 328 (-2.8A)
ADE  A 328 (-4.0A)
 1.24A 4bz6C-3paoA:
undetectable		 4bz6C-3paoA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_D_SHHD700_1
(HISTONE DEACETYLASE
8)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 10 HIS A  16
HIS A 196
ASP A 277
ASP A 278
TYR A  63
 ZN  A 327 (-3.4A)
ZN  A 327 ( 3.5A)
ZN  A 327 ( 2.6A)
ADE  A 328 (-2.8A)
ADE  A 328 (-4.0A)
 1.24A 4bz6D-3paoA:
undetectable		 4bz6D-3paoA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DU2_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT B7)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		4 / 7 ALA A 155
PHE A 111
ALA A 161
LEU A 137
 None
 0.91A 4du2A-3paoA:
undetectable		 4du2A-3paoA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1002_0
(BLUE COPPER OXIDASE
CUEO)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		4 / 4 HIS A  16
HIS A  18
HIS A 220
HIS A 196
 ZN  A 327 (-3.4A)
ADE  A 328 ( 3.0A)
ADE  A 328 ( 4.2A)
ZN  A 327 ( 3.5A)
 0.94A 4ef3A-3paoA:
undetectable		 4ef3A-3paoA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		4 / 7 ASP A 277
ASP A 219
ASP A 100
GLU A 171
 ZN  A 327 ( 2.6A)
None
None
None
 1.22A 4fevB-3paoA:
undetectable		 4fevB-3paoA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_A_SHHA407_1
(HISTONE DEACETYLASE
2)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  16
HIS A 196
ASP A 277
ASP A 278
TYR A  63
 ZN  A 327 (-3.4A)
ZN  A 327 ( 3.5A)
ZN  A 327 ( 2.6A)
ADE  A 328 (-2.8A)
ADE  A 328 (-4.0A)
 1.20A 4lxzA-3paoA:
undetectable		 4lxzA-3paoA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_B_SHHB408_1
(HISTONE DEACETYLASE
2)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 11 HIS A  16
HIS A 196
ASP A 277
ASP A 278
TYR A  63
 ZN  A 327 (-3.4A)
ZN  A 327 ( 3.5A)
ZN  A 327 ( 2.6A)
ADE  A 328 (-2.8A)
ADE  A 328 (-4.0A)
 1.21A 4lxzB-3paoA:
undetectable		 4lxzB-3paoA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_B_SHHB408_1
(HISTONE DEACETYLASE
2)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 11 HIS A 104
HIS A  18
ASP A 278
GLY A  21
TYR A  63
 None
ADE  A 328 ( 3.0A)
ADE  A 328 (-2.8A)
None
ADE  A 328 (-4.0A)
 1.40A 4lxzB-3paoA:
undetectable		 4lxzB-3paoA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_C_SHHC406_1
(HISTONE DEACETYLASE
2)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  16
HIS A 196
ASP A 277
ASP A 278
TYR A  63
 ZN  A 327 (-3.4A)
ZN  A 327 ( 3.5A)
ZN  A 327 ( 2.6A)
ADE  A 328 (-2.8A)
ADE  A 328 (-4.0A)
 1.20A 4lxzC-3paoA:
undetectable		 4lxzC-3paoA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  16
HIS A 196
ASP A 277
ASP A 278
TYR A  63
 ZN  A 327 (-3.4A)
ZN  A 327 ( 3.5A)
ZN  A 327 ( 2.6A)
ADE  A 328 (-2.8A)
ADE  A 328 (-4.0A)
 1.29A 4qa0A-3paoA:
undetectable		 4qa0A-3paoA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_2
(HISTONE DEACETYLASE
8)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 11 HIS A  16
HIS A 196
ASP A 277
ASP A 278
TYR A  63
 ZN  A 327 (-3.4A)
ZN  A 327 ( 3.5A)
ZN  A 327 ( 2.6A)
ADE  A 328 (-2.8A)
ADE  A 328 (-4.0A)
 1.28A 4qa0B-3paoA:
undetectable		 4qa0B-3paoA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  16
HIS A 196
ASP A 277
ASP A 278
TYR A  63
 ZN  A 327 (-3.4A)
ZN  A 327 ( 3.5A)
ZN  A 327 ( 2.6A)
ADE  A 328 (-2.8A)
ADE  A 328 (-4.0A)
 1.28A 4qa2A-3paoA:
undetectable		 4qa2A-3paoA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		6 / 12 HIS A  18
LEU A  56
HIS A 196
HIS A 220
LEU A 251
ASP A 277
 ADE  A 328 ( 3.0A)
ADE  A 328 (-4.6A)
ZN  A 327 ( 3.5A)
ADE  A 328 ( 4.2A)
None
ZN  A 327 ( 2.6A)
 0.36A 4r88A-3paoA:
23.4		 4r88A-3paoA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  18
LEU A  56
HIS A 196
LEU A 251
ASP A 278
 ADE  A 328 ( 3.0A)
ADE  A 328 (-4.6A)
ZN  A 327 ( 3.5A)
None
ADE  A 328 (-2.8A)
 1.46A 4r88A-3paoA:
23.4		 4r88A-3paoA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  18
LEU A 251
HIS A 196
HIS A 220
ASP A 277
 ADE  A 328 ( 3.0A)
None
ZN  A 327 ( 3.5A)
ADE  A 328 ( 4.2A)
ZN  A 327 ( 2.6A)
 1.35A 4r88A-3paoA:
23.4		 4r88A-3paoA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_B_1LDB501_0
(CYTOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		6 / 12 HIS A  18
LEU A  56
HIS A 196
GLU A 199
LEU A 251
ASP A 277
 ADE  A 328 ( 3.0A)
ADE  A 328 (-4.6A)
ZN  A 327 ( 3.5A)
ADE  A 328 (-3.0A)
None
ZN  A 327 ( 2.6A)
 0.32A 4r88B-3paoA:
23.5		 4r88B-3paoA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_B_1LDB501_0
(CYTOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  18
LEU A  56
HIS A 196
LEU A 251
ASP A 278
 ADE  A 328 ( 3.0A)
ADE  A 328 (-4.6A)
ZN  A 327 ( 3.5A)
None
ADE  A 328 (-2.8A)
 1.48A 4r88B-3paoA:
23.5		 4r88B-3paoA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_B_1LDB501_0
(CYTOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  18
PHE A  98
HIS A  16
LEU A  56
ASP A 278
 ADE  A 328 ( 3.0A)
None
ZN  A 327 (-3.4A)
ADE  A 328 (-4.6A)
ADE  A 328 (-2.8A)
 1.48A 4r88B-3paoA:
23.5		 4r88B-3paoA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		6 / 12 HIS A  18
LEU A  56
HIS A 196
GLU A 199
LEU A 251
ASP A 277
 ADE  A 328 ( 3.0A)
ADE  A 328 (-4.6A)
ZN  A 327 ( 3.5A)
ADE  A 328 (-3.0A)
None
ZN  A 327 ( 2.6A)
 0.34A 4r88C-3paoA:
23.5		 4r88C-3paoA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  18
LEU A  56
HIS A 196
LEU A 251
ASP A 278
 ADE  A 328 ( 3.0A)
ADE  A 328 (-4.6A)
ZN  A 327 ( 3.5A)
None
ADE  A 328 (-2.8A)
 1.48A 4r88C-3paoA:
23.5		 4r88C-3paoA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  18
PHE A  98
HIS A  16
LEU A  56
ASP A 278
 ADE  A 328 ( 3.0A)
None
ZN  A 327 (-3.4A)
ADE  A 328 (-4.6A)
ADE  A 328 (-2.8A)
 1.48A 4r88C-3paoA:
23.5		 4r88C-3paoA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_D_1LDD501_0
(CYTOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		6 / 12 HIS A  18
LEU A  56
HIS A 196
GLU A 199
LEU A 251
ASP A 277
 ADE  A 328 ( 3.0A)
ADE  A 328 (-4.6A)
ZN  A 327 ( 3.5A)
ADE  A 328 (-3.0A)
None
ZN  A 327 ( 2.6A)
 0.31A 4r88D-3paoA:
22.2		 4r88D-3paoA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_D_1LDD501_0
(CYTOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  18
LEU A  56
HIS A 196
LEU A 251
ASP A 278
 ADE  A 328 ( 3.0A)
ADE  A 328 (-4.6A)
ZN  A 327 ( 3.5A)
None
ADE  A 328 (-2.8A)
 1.47A 4r88D-3paoA:
22.2		 4r88D-3paoA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_E_1LDE501_0
(CYTOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		6 / 12 HIS A  18
LEU A  56
HIS A 196
GLU A 199
LEU A 251
ASP A 277
 ADE  A 328 ( 3.0A)
ADE  A 328 (-4.6A)
ZN  A 327 ( 3.5A)
ADE  A 328 (-3.0A)
None
ZN  A 327 ( 2.6A)
 0.34A 4r88E-3paoA:
23.5		 4r88E-3paoA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_E_1LDE501_0
(CYTOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  18
LEU A  56
HIS A 196
LEU A 251
ASP A 278
 ADE  A 328 ( 3.0A)
ADE  A 328 (-4.6A)
ZN  A 327 ( 3.5A)
None
ADE  A 328 (-2.8A)
 1.48A 4r88E-3paoA:
23.5		 4r88E-3paoA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_E_1LDE501_0
(CYTOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  18
PHE A  98
HIS A  16
LEU A  56
ASP A 278
 ADE  A 328 ( 3.0A)
None
ZN  A 327 (-3.4A)
ADE  A 328 (-4.6A)
ADE  A 328 (-2.8A)
 1.48A 4r88E-3paoA:
23.5		 4r88E-3paoA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_F_1LDF502_0
(CYTOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		6 / 12 HIS A  18
LEU A  56
HIS A 196
GLU A 199
LEU A 251
ASP A 277
 ADE  A 328 ( 3.0A)
ADE  A 328 (-4.6A)
ZN  A 327 ( 3.5A)
ADE  A 328 (-3.0A)
None
ZN  A 327 ( 2.6A)
 0.30A 4r88F-3paoA:
23.6		 4r88F-3paoA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_F_1LDF502_0
(CYTOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  18
LEU A  56
HIS A 196
LEU A 251
ASP A 278
 ADE  A 328 ( 3.0A)
ADE  A 328 (-4.6A)
ZN  A 327 ( 3.5A)
None
ADE  A 328 (-2.8A)
 1.47A 4r88F-3paoA:
23.6		 4r88F-3paoA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_F_1LDF502_0
(CYTOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  18
PHE A  98
HIS A  16
LEU A  56
ASP A 278
 ADE  A 328 ( 3.0A)
None
ZN  A 327 (-3.4A)
ADE  A 328 (-4.6A)
ADE  A 328 (-2.8A)
 1.46A 4r88F-3paoA:
23.6		 4r88F-3paoA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_A_DGXA1107_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 GLN A 102
GLY A 166
ALA A 195
GLU A 171
ARG A 185
 None
 1.20A 4retA-3paoA:
undetectable		 4retA-3paoA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 GLN A 102
GLY A 166
ALA A 195
GLU A 171
ARG A 185
 None
 1.20A 4retC-3paoA:
undetectable		 4retC-3paoA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA303_0
(THAUMATIN-1)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		4 / 7 LEU A 312
SER A 311
LYS A  12
VAL A 274
 None
 1.14A 4tvtA-3paoA:
undetectable		 4tvtA-3paoA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEI_A_SHHA2004_1
(HDAC6 PROTEIN)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  16
HIS A 196
ASP A 277
ASP A 278
TYR A  63
 ZN  A 327 (-3.4A)
ZN  A 327 ( 3.5A)
ZN  A 327 ( 2.6A)
ADE  A 328 (-2.8A)
ADE  A 328 (-4.0A)
 1.28A 5eeiA-3paoA:
undetectable		 5eeiA-3paoA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEI_B_SHHB801_1
(HDAC6 PROTEIN)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  16
HIS A 196
ASP A 277
ASP A 278
TYR A  63
 ZN  A 327 (-3.4A)
ZN  A 327 ( 3.5A)
ZN  A 327 ( 2.6A)
ADE  A 328 (-2.8A)
ADE  A 328 (-4.0A)
 1.27A 5eeiB-3paoA:
undetectable		 5eeiB-3paoA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF8_A_LBHA2004_1
(HDAC6 PROTEIN)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 ASP A 106
HIS A  16
HIS A 196
ASP A 277
ASP A 278
 None
ZN  A 327 (-3.4A)
ZN  A 327 ( 3.5A)
ZN  A 327 ( 2.6A)
ADE  A 328 (-2.8A)
 1.44A 5ef8A-3paoA:
undetectable		 5ef8A-3paoA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF8_B_LBHB2004_1
(HDAC6 PROTEIN)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 ASP A 106
HIS A  16
HIS A 196
ASP A 277
ASP A 278
 None
ZN  A 327 (-3.4A)
ZN  A 327 ( 3.5A)
ZN  A 327 ( 2.6A)
ADE  A 328 (-2.8A)
 1.46A 5ef8B-3paoA:
undetectable		 5ef8B-3paoA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA601_0
(LACCASE 2)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 196
HIS A  16
HIS A  18
 ZN  A 327 ( 3.5A)
ZN  A 327 (-3.4A)
ADE  A 328 ( 3.0A)
 0.58A 5migA-3paoA:
undetectable		 5migA-3paoA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N9X_A_THRA601_0
(ADENYLATION DOMAIN)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		4 / 7 ASP A 100
PHE A  98
GLY A 166
HIS A 196
 None
None
None
ZN  A 327 ( 3.5A)
 1.04A 5n9xA-3paoA:
undetectable		 5n9xA-3paoA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		4 / 5 PHE A 158
PHE A 162
LEU A 137
PHE A 139
 None
 1.26A 5wauC-3paoA:
undetectable
5wauJ-3paoA:
undetectable		 5wauC-3paoA:
20.29
5wauJ-3paoA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		4 / 5 PHE A 158
PHE A 162
LEU A 137
PHE A 139
 None
 1.27A 5wauc-3paoA:
undetectable
5wauj-3paoA:
undetectable		 5wauc-3paoA:
20.29
5wauj-3paoA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		4 / 5 PHE A 158
PHE A 162
LEU A 137
PHE A 139
 None
 1.26A 5xdqC-3paoA:
undetectable
5xdqJ-3paoA:
undetectable		 5xdqC-3paoA:
20.29
5xdqJ-3paoA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		4 / 5 PHE A 158
PHE A 162
LEU A 137
PHE A 139
 None
 1.27A 5xdqP-3paoA:
undetectable
5xdqW-3paoA:
undetectable		 5xdqP-3paoA:
20.29
5xdqW-3paoA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJS_A_SALA603_0
(VICILIN-LIKE
ANTIMICROBIAL
PEPTIDES 2-2)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 11 GLY A 201
ARG A 223
VAL A 222
PHE A 254
GLY A 198
 None
 1.38A 5yjsA-3paoA:
undetectable		 5yjsA-3paoA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_0
(CYTOCHROME P450 1A1)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 PHE A 162
LEU A 156
PHE A 139
ILE A 118
LEU A 135
 None
 1.11A 6dwnC-3paoA:
undetectable		 6dwnC-3paoA:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  18
LEU A  56
HIS A 196
ASP A 277
ASP A 278
 ADE  A 328 ( 3.0A)
ADE  A 328 (-4.6A)
ZN  A 327 ( 3.5A)
ZN  A 327 ( 2.6A)
ADE  A 328 (-2.8A)
 0.90A 6n91A-3paoA:
41.9		 6n91A-3paoA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		6 / 12 HIS A  18
LEU A  56
LEU A  60
HIS A 196
GLU A 199
ASP A 278
 ADE  A 328 ( 3.0A)
ADE  A 328 (-4.6A)
ADE  A 328 (-4.9A)
ZN  A 327 ( 3.5A)
ADE  A 328 (-3.0A)
ADE  A 328 (-2.8A)
 1.20A 6n91A-3paoA:
41.9		 6n91A-3paoA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		8 / 12 HIS A  18
LEU A  56
LEU A  60
HIS A 196
GLU A 199
HIS A 220
ASP A 277
ASP A 278
 ADE  A 328 ( 3.0A)
ADE  A 328 (-4.6A)
ADE  A 328 (-4.9A)
ZN  A 327 ( 3.5A)
ADE  A 328 (-3.0A)
ADE  A 328 ( 4.2A)
ZN  A 327 ( 2.6A)
ADE  A 328 (-2.8A)
 0.55A 6n91A-3paoA:
41.9		 6n91A-3paoA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 196
LEU A  60
LEU A  56
SER A 247
HIS A  18
 ZN  A 327 ( 3.5A)
ADE  A 328 (-4.9A)
ADE  A 328 (-4.6A)
ADE  A 328 ( 4.5A)
ADE  A 328 ( 3.0A)
 1.09A 6n91A-3paoA:
41.9		 6n91A-3paoA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  18
ASP A 100
LEU A  60
HIS A 220
ASP A 277
 ADE  A 328 ( 3.0A)
None
ADE  A 328 (-4.9A)
ADE  A 328 ( 4.2A)
ZN  A 327 ( 2.6A)
 1.24A 6n91B-3paoA:
42.0		 6n91B-3paoA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  18
LEU A  56
HIS A 196
ASP A 277
ASP A 278
 ADE  A 328 ( 3.0A)
ADE  A 328 (-4.6A)
ZN  A 327 ( 3.5A)
ZN  A 327 ( 2.6A)
ADE  A 328 (-2.8A)
 0.94A 6n91B-3paoA:
42.0		 6n91B-3paoA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  18
LEU A  56
LEU A  60
GLU A 199
ASP A 278
 ADE  A 328 ( 3.0A)
ADE  A 328 (-4.6A)
ADE  A 328 (-4.9A)
ADE  A 328 (-3.0A)
ADE  A 328 (-2.8A)
 1.20A 6n91B-3paoA:
42.0		 6n91B-3paoA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		8 / 12 HIS A  18
LEU A  56
LEU A  60
HIS A 196
GLU A 199
HIS A 220
ASP A 277
ASP A 278
 ADE  A 328 ( 3.0A)
ADE  A 328 (-4.6A)
ADE  A 328 (-4.9A)
ZN  A 327 ( 3.5A)
ADE  A 328 (-3.0A)
ADE  A 328 ( 4.2A)
ZN  A 327 ( 2.6A)
ADE  A 328 (-2.8A)
 0.63A 6n91B-3paoA:
42.0		 6n91B-3paoA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)		 3pao ADENOSINE DEAMINASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 196
LEU A  60
LEU A  56
SER A 247
HIS A  18
 ZN  A 327 ( 3.5A)
ADE  A 328 (-4.9A)
ADE  A 328 (-4.6A)
ADE  A 328 ( 4.5A)
ADE  A 328 ( 3.0A)
 1.06A 6n91B-3paoA:
42.0		 6n91B-3paoA:
15.36