SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pay'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_D_ESTD352_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3pay PUTATIVE ADHESIN
(Bacteroides
ovatus) 		4 / 6 VAL A  56
GLY A 101
LEU A 169
GLU A  36
 None
 0.83A 1fduD-3payA:
undetectable		 1fduD-3payA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_1
(ESTROGEN RECEPTOR
BETA)		 3pay PUTATIVE ADHESIN
(Bacteroides
ovatus) 		5 / 12 THR A 271
LEU A 301
ILE A 324
GLY A 317
LEU A 327
 None
 0.82A 1qknA-3payA:
undetectable		 1qknA-3payA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_ACTH611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3pay PUTATIVE ADHESIN
(Bacteroides
ovatus) 		4 / 6 LEU A 293
LEU A 269
TRP A 299
PHE A 176
 None
 1.15A 1ru9H-3payA:
2.8
1ru9L-3payA:
1.1		 1ru9H-3payA:
22.46
1ru9L-3payA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_L_ACTL611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3pay PUTATIVE ADHESIN
(Bacteroides
ovatus) 		4 / 6 LEU A 293
LEU A 269
TRP A 299
PHE A 176
 None
 1.16A 1rukH-3payA:
2.6
1rukL-3payA:
2.3		 1rukH-3payA:
22.46
1rukL-3payA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA471_1
(CYTOCHROME P450 51)		 3pay PUTATIVE ADHESIN
(Bacteroides
ovatus) 		4 / 8 TYR A 292
PHE A 289
ALA A 276
MET A 270
 None
 1.15A 1x8vA-3payA:
undetectable		 1x8vA-3payA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_2
(AAC(6')-IB)		 3pay PUTATIVE ADHESIN
(Bacteroides
ovatus) 		3 / 3 TRP A 249
GLN A 214
TRP A 207
 None
 1.35A 2vqyA-3payA:
undetectable		 2vqyA-3payA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)		 3pay PUTATIVE ADHESIN
(Bacteroides
ovatus) 		4 / 5 ILE A 275
HIS A 325
TYR A 267
GLY A 317
 None
 1.17A 3b9mA-3payA:
undetectable		 3b9mA-3payA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3pay PUTATIVE ADHESIN
(Bacteroides
ovatus) 		4 / 7 ILE A 217
GLU A 201
HIS A 144
VAL A 100
 None
 1.09A 4a97D-3payA:
undetectable		 4a97D-3payA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y28_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3pay PUTATIVE ADHESIN
(Bacteroides
ovatus) 		5 / 9 PHE A  49
ALA A  77
LEU A  78
GLY A  81
PHE A  61
 None
 1.34A 4y28A-3payA:
undetectable
4y28J-3payA:
undetectable		 4y28A-3payA:
18.10
4y28J-3payA:
10.88