SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pb9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_B_AG2B7011_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 3pb9 GLUTAMINYL-PEPTIDE
CYCLOTRANSFERASE-LIK
E PROTEIN
(Homo
sapiens) 		4 / 5 GLU X 204
ARG X  92
LEU X 201
LEU X  88
 None
 1.19A 1n13B-3pb9X:
undetectable
1n13C-3pb9X:
undetectable		 1n13B-3pb9X:
14.94
1n13C-3pb9X:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3pb9 GLUTAMINYL-PEPTIDE
CYCLOTRANSFERASE-LIK
E PROTEIN
(Homo
sapiens) 		5 / 12 LEU X 217
ALA X 261
MET X 247
VAL X 336
LEU X 220
 None
 1.30A 1s9pB-3pb9X:
undetectable		 1s9pB-3pb9X:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_B_DESB128_1
(TRANSTHYRETIN)		 3pb9 GLUTAMINYL-PEPTIDE
CYCLOTRANSFERASE-LIK
E PROTEIN
(Homo
sapiens) 		5 / 11 ALA X 198
LEU X 194
LEU X 155
ALA X 153
LEU X 217
 None
 1.27A 1tz8A-3pb9X:
undetectable
1tz8B-3pb9X:
undetectable		 1tz8A-3pb9X:
17.43
1tz8B-3pb9X:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_B_DESB128_1
(TRANSTHYRETIN)		 3pb9 GLUTAMINYL-PEPTIDE
CYCLOTRANSFERASE-LIK
E PROTEIN
(Homo
sapiens) 		5 / 11 LEU X 155
ALA X 153
LEU X 217
ALA X 198
LEU X 194
 None
 1.25A 1tz8A-3pb9X:
undetectable
1tz8B-3pb9X:
undetectable		 1tz8A-3pb9X:
17.43
1tz8B-3pb9X:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_1
(MINERALOCORTICOID
RECEPTOR)		 3pb9 GLUTAMINYL-PEPTIDE
CYCLOTRANSFERASE-LIK
E PROTEIN
(Homo
sapiens) 		5 / 12 LEU X 195
LEU X  88
ALA X 200
LEU X 376
THR X 122
 None
 1.50A 1ya3A-3pb9X:
undetectable		 1ya3A-3pb9X:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA5_B_STRB302_1
(MINERALOCORTICOID
RECEPTOR)		 3pb9 GLUTAMINYL-PEPTIDE
CYCLOTRANSFERASE-LIK
E PROTEIN
(Homo
sapiens) 		5 / 12 LEU X 195
LEU X  88
ALA X 200
LEU X 376
THR X 122
 None
 1.45A 2aa5B-3pb9X:
undetectable		 2aa5B-3pb9X:
24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2002_1
(SERUM ALBUMIN)		 3pb9 GLUTAMINYL-PEPTIDE
CYCLOTRANSFERASE-LIK
E PROTEIN
(Homo
sapiens) 		5 / 10 ALA X 373
LEU X  88
LEU X 197
ALA X 200
GLU X 204
 None
 1.17A 2bxeA-3pb9X:
undetectable		 2bxeA-3pb9X:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_C_SPMC1434_1
(NITROALKANE OXIDASE)		 3pb9 GLUTAMINYL-PEPTIDE
CYCLOTRANSFERASE-LIK
E PROTEIN
(Homo
sapiens) 		5 / 12 GLN X  87
LEU X 205
GLU X 204
VAL X  84
LEU X 382
 None
 1.25A 2c12C-3pb9X:
undetectable		 2c12C-3pb9X:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_F_SPMF1433_1
(NITROALKANE OXIDASE)		 3pb9 GLUTAMINYL-PEPTIDE
CYCLOTRANSFERASE-LIK
E PROTEIN
(Homo
sapiens) 		5 / 11 GLN X  87
LEU X 205
GLU X 204
VAL X  84
LEU X 382
 None
 1.21A 2c12F-3pb9X:
undetectable		 2c12F-3pb9X:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_B_ROFB902_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3pb9 GLUTAMINYL-PEPTIDE
CYCLOTRANSFERASE-LIK
E PROTEIN
(Homo
sapiens) 		5 / 12 LEU X 368
PRO X 276
THR X 344
ILE X 342
PHE X 278
 None
 1.49A 3g4lB-3pb9X:
undetectable		 3g4lB-3pb9X:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_1
(O-METHYLTRANSFERASE)		 3pb9 GLUTAMINYL-PEPTIDE
CYCLOTRANSFERASE-LIK
E PROTEIN
(Homo
sapiens) 		3 / 3 ASP X 170
PHE X 148
SER X 240
 None
 0.95A 3i5uB-3pb9X:
undetectable		 3i5uB-3pb9X:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2O_C_AG2C1002_1
(BIOSYNTHETIC
ARGININE
DECARBOXYLASE)		 3pb9 GLUTAMINYL-PEPTIDE
CYCLOTRANSFERASE-LIK
E PROTEIN
(Homo
sapiens) 		4 / 8 ASP X 186
LEU X 270
ASP X 326
ASP X 327
 ZN  X 400 ( 2.1A)
1BN  X 390 ( 4.7A)
1BN  X 390 ( 4.2A)
None
 1.21A 3n2oC-3pb9X:
undetectable
3n2oD-3pb9X:
undetectable		 3n2oC-3pb9X:
20.57
3n2oD-3pb9X:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OI8_A_ADNA2_1
(UNCHARACTERIZED
PROTEIN)		 3pb9 GLUTAMINYL-PEPTIDE
CYCLOTRANSFERASE-LIK
E PROTEIN
(Homo
sapiens) 		4 / 6 HIS X 351
PRO X 347
LEU X 270
ASP X 326
 ZN  X 400 ( 3.2A)
None
1BN  X 390 ( 4.7A)
1BN  X 390 ( 4.2A)
 1.10A 3oi8A-3pb9X:
undetectable		 3oi8A-3pb9X:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		 3pb9 GLUTAMINYL-PEPTIDE
CYCLOTRANSFERASE-LIK
E PROTEIN
(Homo
sapiens) 		3 / 3 ASP X 327
GLU X 226
GLY X 224
 None
ZN  X 400 ( 2.1A)
None
 0.70A 3w9tA-3pb9X:
undetectable		 3w9tA-3pb9X:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PQA_A_X8ZA401_1
(SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE)		 3pb9 GLUTAMINYL-PEPTIDE
CYCLOTRANSFERASE-LIK
E PROTEIN
(Homo
sapiens) 		5 / 11 HIS X 168
ASP X 186
GLU X 225
GLU X 226
HIS X 351
 None
ZN  X 400 ( 2.1A)
1BN  X 390 (-3.6A)
ZN  X 400 ( 2.1A)
ZN  X 400 ( 3.2A)
 0.32A 4pqaA-3pb9X:
22.5		 4pqaA-3pb9X:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_F_PARF500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 3pb9 GLUTAMINYL-PEPTIDE
CYCLOTRANSFERASE-LIK
E PROTEIN
(Homo
sapiens) 		5 / 11 PHE X 174
ASP X 269
ASP X 327
TYR X 238
GLY X 224
 None
1BN  X 390 (-3.3A)
None
None
None
 1.45A 4qb9F-3pb9X:
0.8		 4qb9F-3pb9X:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_A_ADNA302_1
(FLUORINASE)		 3pb9 GLUTAMINYL-PEPTIDE
CYCLOTRANSFERASE-LIK
E PROTEIN
(Homo
sapiens) 		4 / 7 ASP X 147
THR X 138
PRO X 145
THR X 141
 None
 1.13A 5b6iA-3pb9X:
undetectable		 5b6iA-3pb9X:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_1
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 3pb9 GLUTAMINYL-PEPTIDE
CYCLOTRANSFERASE-LIK
E PROTEIN
(Homo
sapiens) 		3 / 3 ARG X 124
LYS X 117
GLU X 120
 None
 0.60A 5d0yA-3pb9X:
undetectable		 5d0yA-3pb9X:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3pb9 GLUTAMINYL-PEPTIDE
CYCLOTRANSFERASE-LIK
E PROTEIN
(Homo
sapiens) 		4 / 4 ALA X 244
PRO X 337
LEU X 163
HIS X 162
 None
 1.31A 5eskA-3pb9X:
undetectable		 5eskA-3pb9X:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_2
(CYP51 VARIANT1)		 3pb9 GLUTAMINYL-PEPTIDE
CYCLOTRANSFERASE-LIK
E PROTEIN
(Homo
sapiens) 		3 / 3 PRO X 320
LEU X 339
SER X 323
 None
 0.61A 5fsaB-3pb9X:
undetectable		 5fsaB-3pb9X:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_B_SAMB1304_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 3pb9 GLUTAMINYL-PEPTIDE
CYCLOTRANSFERASE-LIK
E PROTEIN
(Homo
sapiens) 		3 / 3 ASN X 150
TYR X 169
CYH X 167
 None
 1.00A 5lsuB-3pb9X:
undetectable		 5lsuB-3pb9X:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M35_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3pb9 GLUTAMINYL-PEPTIDE
CYCLOTRANSFERASE-LIK
E PROTEIN
(Homo
sapiens) 		4 / 5 PHE X 289
THR X 277
GLN X 316
ARG X 293
 None
 1.33A 5m35A-3pb9X:
undetectable		 5m35A-3pb9X:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_2
(WTFP-TAG,GP41)		 3pb9 GLUTAMINYL-PEPTIDE
CYCLOTRANSFERASE-LIK
E PROTEIN
(Homo
sapiens) 		3 / 3 LEU X 271
LEU X 270
TRP X 350
 None
1BN  X 390 ( 4.7A)
1BN  X 390 (-4.8A)
 0.94A 5nwuA-3pb9X:
undetectable		 5nwuA-3pb9X:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_0
(REGULATORY PROTEIN
TETR)		 3pb9 GLUTAMINYL-PEPTIDE
CYCLOTRANSFERASE-LIK
E PROTEIN
(Homo
sapiens) 		5 / 12 ALA X 166
ILE X 329
ARG X 333
VAL X 338
PHE X 282
 None
 1.43A 5vlmE-3pb9X:
undetectable		 5vlmE-3pb9X:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_B_CXQB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 3pb9 GLUTAMINYL-PEPTIDE
CYCLOTRANSFERASE-LIK
E PROTEIN
(Homo
sapiens) 		4 / 6 VAL X  84
LEU X 201
LEU X 197
LEU X 380
 None
 0.89A 6f6sA-3pb9X:
undetectable
6f6sB-3pb9X:
undetectable		 6f6sA-3pb9X:
14.37
6f6sB-3pb9X:
13.77