SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pbl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA6_0
(GRAMICIDIN A)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Homo
sapiens;
Escherichia
virus
T4) 		3 / 3 ALA A  79
VAL A  82
TRP A  85
 None
 1.01A 1c4dA-3pblA:
undetectable
1c4dB-3pblA:
undetectable		 1c4dA-3pblA:
2.49
1c4dB-3pblA:
2.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_A_CCSA47_0
(GLUTATHIONE
S-TRANSFERASE)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Homo
sapiens;
Escherichia
virus
T4) 		4 / 7 LEU A1033
LEU A1015
GLY A1028
LEU A1066
 None
 0.87A 1gtiA-3pblA:
undetectable		 1gtiA-3pblA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_2
(HMG-COA REDUCTASE)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 8 SER A 192
VAL A 164
SER A 165
ASP A 110
 ETQ  A1200 (-3.3A)
None
None
ETQ  A1200 (-3.5A)
 1.01A 1hwiB-3pblA:
undetectable		 1hwiB-3pblA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_A_117A2_1
(HMG-COA REDUCTASE)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 8 SER A 192
VAL A 164
SER A 165
ASP A 110
 ETQ  A1200 (-3.3A)
None
None
ETQ  A1200 (-3.5A)
 0.95A 1hwkA-3pblA:
undetectable		 1hwkA-3pblA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_A_117A2_1
(HMG-COA REDUCTASE)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 8 SER A 196
VAL A 164
SER A 165
ASP A 110
 ETQ  A1200 ( 4.6A)
None
None
ETQ  A1200 (-3.5A)
 1.22A 1hwkA-3pblA:
undetectable		 1hwkA-3pblA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_C_117C4_1
(HMG-COA REDUCTASE)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 8 SER A 192
VAL A 164
SER A 165
ASP A 110
 ETQ  A1200 (-3.3A)
None
None
ETQ  A1200 (-3.5A)
 0.98A 1hwkC-3pblA:
undetectable		 1hwkC-3pblA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_C_117C4_1
(HMG-COA REDUCTASE)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 8 SER A 196
VAL A 164
SER A 165
ASP A 110
 ETQ  A1200 ( 4.6A)
None
None
ETQ  A1200 (-3.5A)
 1.24A 1hwkC-3pblA:
undetectable		 1hwkC-3pblA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_D_117D3_2
(HMG-COA REDUCTASE)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 8 SER A 192
VAL A 164
SER A 165
ASP A 110
 ETQ  A1200 (-3.3A)
None
None
ETQ  A1200 (-3.5A)
 0.97A 1hwkD-3pblA:
undetectable		 1hwkD-3pblA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_D_117D3_2
(HMG-COA REDUCTASE)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 8 SER A 196
VAL A 164
SER A 165
ASP A 110
 ETQ  A1200 ( 4.6A)
None
None
ETQ  A1200 (-3.5A)
 1.22A 1hwkD-3pblA:
undetectable		 1hwkD-3pblA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_A_REAA502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 ALA A1129
PHE A1153
LEU A1133
ALA A1130
ILE A1078
 None
 0.99A 2aclA-3pblA:
2.6
2aclE-3pblA:
2.6		 2aclA-3pblA:
18.63
2aclE-3pblA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_A_PXLA1003_1
(PYRIDOXINE KINASE)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 8 SER A 192
VAL A 111
PRO A 167
TYR A 191
 ETQ  A1200 (-3.3A)
ETQ  A1200 (-3.4A)
None
None
 1.08A 2ddwA-3pblA:
undetectable		 2ddwA-3pblA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_A_SALA2006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 6 PHE A1153
VAL A1087
LEU A1118
ALA A1129
 None
 0.96A 2e1qA-3pblA:
undetectable		 2e1qA-3pblA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_C_SALC4006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 6 PHE A1153
VAL A1087
LEU A1118
ALA A1129
 None
 0.94A 2e1qC-3pblA:
undetectable		 2e1qC-3pblA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_2
(ANDROGEN RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 6 TRP A1138
MET A1102
MET A1106
LEU A1099
 None
 1.29A 2oz7A-3pblA:
undetectable		 2oz7A-3pblA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_D_TC9D1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 8 THR A1034
TYR A1025
ILE A1017
SER A1036
 None
 1.07A 2xytE-3pblA:
undetectable		 2xytE-3pblA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_G_TC9G1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 8 THR A1034
TYR A1025
ILE A1017
SER A1036
 None
 1.00A 2xytH-3pblA:
undetectable		 2xytH-3pblA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_H_TC9H1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 7 THR A1034
TYR A1025
ILE A1017
SER A1036
 None
 1.05A 2xytI-3pblA:
undetectable		 2xytI-3pblA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 ASP A 110
VAL A 111
SER A 192
PHE A 345
PHE A 346
TYR A 373
 ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 (-3.3A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 1.06A 2y00A-3pblA:
32.6		 2y00A-3pblA:
29.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 12 LEU A  89
ASP A 110
VAL A 111
SER A 192
PHE A 345
PHE A 346
TYR A 373
 None
ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 (-3.3A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 0.95A 2y00A-3pblA:
32.6		 2y00A-3pblA:
29.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 12 LEU A  89
ASP A 110
VAL A 111
SER A 196
PHE A 345
PHE A 346
TYR A 373
 None
ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 ( 4.6A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 0.71A 2y00A-3pblA:
32.6		 2y00A-3pblA:
29.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 VAL A  87
VAL A 111
SER A 196
PHE A 345
PHE A 346
TYR A 373
 None
ETQ  A1200 (-3.4A)
ETQ  A1200 ( 4.6A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 1.29A 2y00A-3pblA:
32.6		 2y00A-3pblA:
29.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 ASP A 110
VAL A 111
SER A 192
PHE A 345
PHE A 346
TYR A 373
 ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 (-3.3A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 1.09A 2y00B-3pblA:
32.3		 2y00B-3pblA:
29.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 12 LEU A  89
ASP A 110
VAL A 111
SER A 192
PHE A 345
PHE A 346
TYR A 373
 None
ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 (-3.3A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 0.93A 2y00B-3pblA:
32.3		 2y00B-3pblA:
29.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 12 LEU A  89
ASP A 110
VAL A 111
SER A 196
PHE A 345
PHE A 346
TYR A 373
 None
ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 ( 4.6A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 0.72A 2y00B-3pblA:
32.3		 2y00B-3pblA:
29.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 VAL A  87
VAL A 111
SER A 196
PHE A 346
TYR A 373
 None
ETQ  A1200 (-3.4A)
ETQ  A1200 ( 4.6A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 1.38A 2y00B-3pblA:
32.3		 2y00B-3pblA:
29.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 ASP A 110
SER A 192
PHE A 345
PHE A 346
TYR A 373
 ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.3A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 0.95A 2y01A-3pblA:
32.3		 2y01A-3pblA:
29.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 VAL A  87
SER A 192
PHE A 345
PHE A 346
TYR A 373
 None
ETQ  A1200 (-3.3A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 1.30A 2y01A-3pblA:
32.3		 2y01A-3pblA:
29.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 ASP A 110
VAL A 111
SER A 192
PHE A 345
PHE A 346
TYR A 373
 ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 (-3.3A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 1.07A 2y01B-3pblA:
32.0		 2y01B-3pblA:
29.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 12 LEU A  89
ASP A 110
VAL A 111
SER A 192
PHE A 345
PHE A 346
TYR A 373
 None
ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 (-3.3A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 0.92A 2y01B-3pblA:
32.0		 2y01B-3pblA:
29.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 12 LEU A  89
ASP A 110
VAL A 111
SER A 196
PHE A 345
PHE A 346
TYR A 373
 None
ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 ( 4.6A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 0.71A 2y01B-3pblA:
32.0		 2y01B-3pblA:
29.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 VAL A  87
VAL A 111
SER A 196
PHE A 346
TYR A 373
 None
ETQ  A1200 (-3.4A)
ETQ  A1200 ( 4.6A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 1.37A 2y01B-3pblA:
32.0		 2y01B-3pblA:
29.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 ASP A 110
VAL A 111
SER A 192
PHE A 345
PHE A 346
TYR A 373
 ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 (-3.3A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 0.87A 2y03A-3pblA:
32.3		 2y03A-3pblA:
29.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 ASP A 110
VAL A 111
SER A 192
PHE A 345
PHE A 346
TYR A 373
 ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 (-3.3A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 1.02A 2y03A-3pblA:
32.3		 2y03A-3pblA:
29.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 ASP A 110
VAL A 111
SER A 196
PHE A 345
PHE A 346
TYR A 373
 ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 ( 4.6A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 0.65A 2y03A-3pblA:
32.3		 2y03A-3pblA:
29.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 ASP A 110
VAL A 111
SER A 192
PHE A 345
PHE A 346
TYR A 373
 ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 (-3.3A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 0.85A 2y03B-3pblA:
32.3		 2y03B-3pblA:
29.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 ASP A 110
VAL A 111
SER A 192
PHE A 345
PHE A 346
TYR A 373
 ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 (-3.3A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 1.03A 2y03B-3pblA:
32.3		 2y03B-3pblA:
29.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 ASP A 110
VAL A 111
SER A 196
PHE A 345
PHE A 346
TYR A 373
 ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 ( 4.6A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 0.63A 2y03B-3pblA:
32.3		 2y03B-3pblA:
29.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y04_A_68HA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 11 ASP A 110
VAL A 111
SER A 192
SER A 196
PHE A 345
PHE A 346
TYR A 373
 ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 (-3.3A)
ETQ  A1200 ( 4.6A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 0.71A 2y04A-3pblA:
32.2		 2y04A-3pblA:
29.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y04_B_68HB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 12 ASP A 110
VAL A 111
SER A 192
SER A 196
PHE A 345
PHE A 346
TYR A 373
 ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 (-3.3A)
ETQ  A1200 ( 4.6A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 0.69A 2y04B-3pblA:
32.1		 2y04B-3pblA:
29.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_A_SALA1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 8 PHE A1153
VAL A1087
LEU A1118
ALA A1129
 None
 0.94A 3ax7A-3pblA:
undetectable		 3ax7A-3pblA:
16.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D4S_A_TIMA401_1
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 ASP A 110
VAL A 111
SER A 192
TRP A 342
PHE A 346
TYR A 373
 ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 (-3.3A)
None
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 0.71A 3d4sA-3pblA:
28.1		 3d4sA-3pblA:
56.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D4S_A_TIMA401_1
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 ASP A 110
VAL A 111
SER A 192
TRP A 342
TYR A 365
TYR A 373
 ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 (-3.3A)
None
None
ETQ  A1200 (-4.4A)
 1.03A 3d4sA-3pblA:
28.1		 3d4sA-3pblA:
56.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D4S_A_TIMA401_2
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		3 / 3 THR A 115
SER A 196
PHE A 345
 None
ETQ  A1200 ( 4.6A)
ETQ  A1200 (-4.4A)
 0.75A 3d4sA-3pblA:
37.7		 3d4sA-3pblA:
56.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC6_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 11 ALA A1129
PHE A1153
LEU A1133
ALA A1130
ILE A1078
 None
 1.02A 3fc6A-3pblA:
undetectable		 3fc6A-3pblA:
18.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 ASP A 110
VAL A 111
SER A 192
PHE A 345
PHE A 346
TYR A 373
 ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 (-3.3A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 1.07A 3nyaA-3pblA:
37.3		 3nyaA-3pblA:
56.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 12 ASP A 110
VAL A 111
SER A 192
SER A 196
PHE A 345
PHE A 346
TYR A 373
 ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 (-3.3A)
ETQ  A1200 ( 4.6A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 0.81A 3nyaA-3pblA:
37.3		 3nyaA-3pblA:
56.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RZE_A_D7VA1201_1
(HISTAMINE H1
RECEPTOR, LYSOZYME
CHIMERA)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 ASP A 110
THR A 115
ILE A 118
TRP A 342
PHE A 346
TYR A 373
 ETQ  A1200 (-3.5A)
None
None
None
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 0.53A 3rzeA-3pblA:
36.3		 3rzeA-3pblA:
54.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_A_SALA1344_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 7 PHE A1153
VAL A1087
LEU A1118
ALA A1129
 None
 0.96A 3uniA-3pblA:
undetectable		 3uniA-3pblA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AMJ_A_CVDA1359_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 ASP A 110
VAL A 111
SER A 192
PHE A 346
TYR A 373
 ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 (-3.3A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 1.19A 4amjA-3pblA:
32.6		 4amjA-3pblA:
29.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AMJ_A_CVDA1359_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		8 / 12 ASP A 110
VAL A 111
SER A 192
SER A 196
TRP A 342
PHE A 345
PHE A 346
TYR A 373
 ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 (-3.3A)
ETQ  A1200 ( 4.6A)
None
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 0.71A 4amjA-3pblA:
32.6		 4amjA-3pblA:
29.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AMJ_A_CVDA1359_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 ASP A 110
VAL A 111
SER A 196
PHE A 345
PHE A 346
 ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 ( 4.6A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
 1.47A 4amjA-3pblA:
32.6		 4amjA-3pblA:
29.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AMJ_B_CVDB1360_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		8 / 12 LEU A  89
ASP A 110
SER A 192
SER A 196
TRP A 342
PHE A 345
PHE A 346
TYR A 373
 None
ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.3A)
ETQ  A1200 ( 4.6A)
None
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 0.77A 4amjB-3pblA:
32.4		 4amjB-3pblA:
29.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AMJ_B_CVDB1360_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 LEU A  89
ASP A 110
SER A 196
PHE A 345
PHE A 346
 None
ETQ  A1200 (-3.5A)
ETQ  A1200 ( 4.6A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
 1.40A 4amjB-3pblA:
32.4		 4amjB-3pblA:
29.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 GLY A  48
ALA A  42
ASP A  75
ALA A  72
VAL A  50
 None
 1.28A 4df3A-3pblA:
undetectable		 4df3A-3pblA:
18.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IAQ_A_2GMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 ASP A 110
TRP A 342
PHE A 345
PHE A 346
THR A 369
 ETQ  A1200 (-3.5A)
None
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.5A)
 0.67A 4iaqA-3pblA:
30.9		 4iaqA-3pblA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LDO_A_ALEA1402_1
(LYSOZYME, BETA-2
ADRENERGIC RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 10 ASP A 110
VAL A 111
SER A 192
PHE A 345
TYR A 373
 ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 (-3.3A)
ETQ  A1200 (-4.4A)
ETQ  A1200 (-4.4A)
 0.84A 4ldoA-3pblA:
26.8		 4ldoA-3pblA:
31.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LDO_A_ALEA1402_1
(LYSOZYME, BETA-2
ADRENERGIC RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 10 ASP A 110
VAL A 111
SER A 196
PHE A 345
TYR A 373
 ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 ( 4.6A)
ETQ  A1200 (-4.4A)
ETQ  A1200 (-4.4A)
 0.53A 4ldoA-3pblA:
26.8		 4ldoA-3pblA:
31.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 4 ASN A  47
SER A 117
ALA A  72
VAL A  69
 None
 1.06A 5nm5A-3pblA:
undetectable		 5nm5A-3pblA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIG_A_EDTA501_0
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Homo
sapiens;
Escherichia
virus
T4) 		4 / 6 THR A  64
ASN A  65
ARG A 128
GLU A 389
 None
 0.85A 5uigA-3pblA:
28.3		 5uigA-3pblA:
29.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A93_A_8NUA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Homo
sapiens;
Escherichia
virus
T4) 		7 / 12 THR A 115
ILE A 118
PHE A 338
TRP A 342
PHE A 345
PHE A 346
TYR A 373
 None
None
None
None
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 0.54A 6a93A-3pblA:
31.4		 6a93A-3pblA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A93_B_8NUB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 VAL A 111
THR A 115
TRP A 342
PHE A 345
PHE A 346
 ETQ  A1200 (-3.4A)
None
None
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
 0.44A 6a93B-3pblA:
33.4		 6a93B-3pblA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A93_B_8NUB3001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Homo
sapiens;
Escherichia
virus
T4) 		4 / 5 ASP A 110
ILE A 118
PHE A 338
TYR A 373
 ETQ  A1200 (-3.5A)
None
None
ETQ  A1200 (-4.4A)
 0.46A 6a93B-3pblA:
33.4		 6a93B-3pblA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Homo
sapiens;
Escherichia
virus
T4) 		6 / 12 VAL A 189
SER A 196
PHE A 338
TRP A 342
PHE A 345
PHE A 346
 ETQ  A1200 ( 4.2A)
ETQ  A1200 ( 4.6A)
None
None
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
 0.59A 6a94A-3pblA:
33.3		 6a94A-3pblA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Homo
sapiens;
Escherichia
virus
T4) 		8 / 12 VAL A 111
THR A 115
VAL A 189
SER A 196
PHE A 338
TRP A 342
PHE A 345
PHE A 346
 ETQ  A1200 (-3.4A)
None
ETQ  A1200 ( 4.2A)
ETQ  A1200 ( 4.6A)
None
None
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
 0.62A 6a94B-3pblA:
32.9		 6a94B-3pblA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CM4_A_8NUA2001_0
(D(2) DOPAMINE
RECEPTOR, ENDOLYSIN
CHIMERA)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Homo
sapiens;
Escherichia
virus
T4) 		8 / 12 PHE A 106
VAL A 111
THR A 115
PHE A 338
TRP A 342
PHE A 346
THR A 369
TYR A 373
 ETQ  A1200 (-4.8A)
ETQ  A1200 (-3.4A)
None
None
None
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.5A)
ETQ  A1200 (-4.4A)
 0.69A 6cm4A-3pblA:
38.3		 6cm4A-3pblA:
74.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CM4_A_8NUA2001_0
(D(2) DOPAMINE
RECEPTOR, ENDOLYSIN
CHIMERA)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 VAL A 111
CYH A 114
THR A 115
TRP A 342
THR A 369
 ETQ  A1200 (-3.4A)
ETQ  A1200 (-4.0A)
None
None
ETQ  A1200 (-4.5A)
 1.16A 6cm4A-3pblA:
38.3		 6cm4A-3pblA:
74.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CM4_A_8NUA2001_0
(D(2) DOPAMINE
RECEPTOR, ENDOLYSIN
CHIMERA)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 VAL A 111
CYH A 114
THR A 115
TRP A 342
TYR A 365
 ETQ  A1200 (-3.4A)
ETQ  A1200 (-4.0A)
None
None
None
 1.34A 6cm4A-3pblA:
38.3		 6cm4A-3pblA:
74.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CM4_A_8NUA2001_0
(D(2) DOPAMINE
RECEPTOR, ENDOLYSIN
CHIMERA)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 VAL A 111
SER A 192
PHE A 338
TRP A 342
PHE A 346
 ETQ  A1200 (-3.4A)
ETQ  A1200 (-3.3A)
None
None
ETQ  A1200 ( 4.5A)
 0.98A 6cm4A-3pblA:
38.3		 6cm4A-3pblA:
74.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CM4_A_8NUA2001_0
(D(2) DOPAMINE
RECEPTOR, ENDOLYSIN
CHIMERA)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Homo
sapiens;
Escherichia
virus
T4) 		6 / 12 VAL A 111
THR A 115
PHE A 338
TRP A 342
PHE A 346
TYR A 365
 ETQ  A1200 (-3.4A)
None
None
None
ETQ  A1200 ( 4.5A)
None
 0.90A 6cm4A-3pblA:
38.3		 6cm4A-3pblA:
74.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRZ_A_H8JA1206_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 VAL A 111
THR A 115
PHE A 188
PHE A 346
TYR A 373
 ETQ  A1200 (-3.4A)
None
None
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 0.75A 6drzA-3pblA:
14.7		 6drzA-3pblA:
29.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRZ_A_H8JA1206_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 VAL A 111
THR A 115
PHE A 345
PHE A 346
TYR A 373
 ETQ  A1200 (-3.4A)
None
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 0.70A 6drzA-3pblA:
14.7		 6drzA-3pblA:
29.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7J_A_5FWA401_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 ASP A 110
VAL A 111
SER A 192
PHE A 345
PHE A 346
 ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 (-3.3A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
 1.24A 6h7jA-3pblA:
28.8		 6h7jA-3pblA:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7J_A_5FWA401_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Homo
sapiens;
Escherichia
virus
T4) 		6 / 12 ASP A 110
VAL A 111
SER A 192
PHE A 345
PHE A 346
TYR A 373
 ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 (-3.3A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 0.79A 6h7jA-3pblA:
28.8		 6h7jA-3pblA:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7J_A_5FWA401_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Homo
sapiens;
Escherichia
virus
T4) 		6 / 12 ASP A 110
VAL A 111
SER A 196
PHE A 345
PHE A 346
TYR A 373
 ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 ( 4.6A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 0.53A 6h7jA-3pblA:
28.8		 6h7jA-3pblA:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7J_B_5FWB402_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 ASP A 110
VAL A 111
SER A 192
PHE A 345
PHE A 346
 ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 (-3.3A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
 1.25A 6h7jB-3pblA:
16.6		 6h7jB-3pblA:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7J_B_5FWB402_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Homo
sapiens;
Escherichia
virus
T4) 		6 / 12 ASP A 110
VAL A 111
SER A 192
PHE A 345
PHE A 346
TYR A 373
 ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 (-3.3A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 0.78A 6h7jB-3pblA:
16.6		 6h7jB-3pblA:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7J_B_5FWB402_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Homo
sapiens;
Escherichia
virus
T4) 		6 / 12 ASP A 110
VAL A 111
SER A 196
PHE A 345
PHE A 346
TYR A 373
 ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 ( 4.6A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 0.53A 6h7jB-3pblA:
16.6		 6h7jB-3pblA:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_A_68HA504_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 ASP A 110
VAL A 111
SER A 192
PHE A 345
PHE A 346
 ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 (-3.3A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
 1.27A 6h7mA-3pblA:
28.8		 6h7mA-3pblA:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_A_68HA504_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Homo
sapiens;
Escherichia
virus
T4) 		6 / 12 ASP A 110
VAL A 111
SER A 192
PHE A 345
PHE A 346
TYR A 373
 ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 (-3.3A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 0.85A 6h7mA-3pblA:
28.8		 6h7mA-3pblA:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_A_68HA504_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Homo
sapiens;
Escherichia
virus
T4) 		6 / 12 ASP A 110
VAL A 111
SER A 196
PHE A 345
PHE A 346
TYR A 373
 ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 ( 4.6A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 0.51A 6h7mA-3pblA:
28.8		 6h7mA-3pblA:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 ASP A 110
VAL A 111
SER A 192
PHE A 345
PHE A 346
 ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 (-3.3A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
 1.27A 6h7mB-3pblA:
16.5		 6h7mB-3pblA:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Homo
sapiens;
Escherichia
virus
T4) 		6 / 12 ASP A 110
VAL A 111
SER A 192
PHE A 345
PHE A 346
TYR A 373
 ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 (-3.3A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 0.85A 6h7mB-3pblA:
16.5		 6h7mB-3pblA:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Homo
sapiens;
Escherichia
virus
T4) 		6 / 12 ASP A 110
VAL A 111
SER A 196
PHE A 345
PHE A 346
TYR A 373
 ETQ  A1200 (-3.5A)
ETQ  A1200 (-3.4A)
ETQ  A1200 ( 4.6A)
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 0.51A 6h7mB-3pblA:
16.5		 6h7mB-3pblA:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_A_H98A501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 VAL A 111
TRP A 342
PHE A 345
PHE A 346
TYR A 373
 ETQ  A1200 (-3.4A)
None
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 0.51A 6iblA-3pblA:
28.8		 6iblA-3pblA:
27.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_B_H98B501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 VAL A 111
TRP A 342
PHE A 345
PHE A 346
TYR A 373
 ETQ  A1200 (-3.4A)
None
ETQ  A1200 (-4.4A)
ETQ  A1200 ( 4.5A)
ETQ  A1200 (-4.4A)
 0.53A 6iblB-3pblA:
28.8		 6iblB-3pblA:
27.27