SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pbp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRG_A_ADNA300_1
(ALPHA-MOMORCHARIN)		 3pbp NUCLEOPORIN
NUP116/NSP116
(Saccharomyces
cerevisiae) 		5 / 9 ILE B1003
PHE B1026
GLY B1001
ILE B1053
ALA B1051
 None
 1.31A 1mrgA-3pbpB:
undetectable		 1mrgA-3pbpB:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB926_0
(FERROCHELATASE)		 3pbp NUCLEOPORIN
NUP116/NSP116
(Saccharomyces
cerevisiae) 		5 / 10 LEU B1011
ILE B1047
VAL B1022
GLY B1021
MET B 966
 None
 1.03A 2qd4B-3pbpB:
undetectable		 2qd4B-3pbpB:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_0
(WBDD)		 3pbp NUCLEOPORIN
NUP116/NSP116
(Saccharomyces
cerevisiae) 		5 / 12 GLY B1020
ASN B 967
ILE B1024
VAL B 995
ILE B1003
 None
 0.98A 4ax8A-3pbpB:
undetectable		 4ax8A-3pbpB:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_0
(METHYLTRANSFERASE
WBDD)		 3pbp NUCLEOPORIN
NUP116/NSP116
(Saccharomyces
cerevisiae) 		5 / 12 GLY B1020
ASN B 967
ILE B1024
VAL B 995
ILE B1003
 None
 0.96A 4aztA-3pbpB:
undetectable		 4aztA-3pbpB:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_0
(WBDD)		 3pbp NUCLEOPORIN
NUP116/NSP116
(Saccharomyces
cerevisiae) 		5 / 12 GLY B1020
ASN B 967
ILE B1024
VAL B 995
ILE B1003
 None
 0.97A 4azvA-3pbpB:
undetectable		 4azvA-3pbpB:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 3pbp NUCLEOPORIN
NUP116/NSP116
(Saccharomyces
cerevisiae) 		5 / 9 ILE B1003
PHE B1026
GLY B1001
ILE B1053
ALA B1051
 None
 1.33A 4yp2B-3pbpB:
undetectable		 4yp2B-3pbpB:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 3pbp NUCLEOPORIN
NUP116/NSP116
(Saccharomyces
cerevisiae) 		5 / 9 ILE B1003
PHE B1026
GLY B1001
ILE B1053
ALA B1051
 None
 1.32A 5cf9B-3pbpB:
undetectable		 5cf9B-3pbpB:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M24_A_9CRA501_1
(RETINOIC ACID
RECEPTOR GAMMA)		 3pbp NUCLEOPORIN
NUP116/NSP116
(Saccharomyces
cerevisiae) 		5 / 12 PHE B1005
ALA B1109
GLY B 996
LEU B1019
ILE B1033
 None
 1.03A 5m24A-3pbpB:
undetectable		 5m24A-3pbpB:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 3pbp NUCLEOPORIN
NUP116/NSP116
(Saccharomyces
cerevisiae) 		3 / 3 LYS B1067
PRO B1068
LYS B1070
 None
 1.19A 5y9yA-3pbpB:
undetectable		 5y9yA-3pbpB:
23.38