SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pco'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		5 / 10 LEU B 724
VAL B 738
ILE B 758
GLU B 783
LEU B 785
 None
 1.11A 1cqpA-3pcoB:
undetectable
1cqpB-3pcoB:
undetectable		 1cqpA-3pcoB:
13.01
1cqpB-3pcoB:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		4 / 7 VAL B 624
LEU B 617
VAL B 662
LEU B 502
 None
 0.81A 1cqpA-3pcoB:
undetectable
1cqpB-3pcoB:
undetectable		 1cqpA-3pcoB:
13.01
1cqpB-3pcoB:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4001_1
(SERUM ALBUMIN)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		4 / 5 ARG B 177
ALA B 176
ASP B 168
GLY B 171
 None
 1.13A 1e7bA-3pcoB:
undetectable		 1e7bA-3pcoB:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTB_A_PZQA901_0
(GLUTATHIONE
S-TRANSFERASE)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli;
Escherichia
coli) 		3 / 3 GLN B 588
TYR A 194
ARG A 195
 None
None
AMP  A 992 (-4.0A)
 0.95A 1gtbA-3pcoB:
undetectable		 1gtbA-3pcoB:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_B_TESB904_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
(Escherichia
coli) 		4 / 7 TYR A 194
VAL A 109
ILE A 113
GLU A 132
 None
 1.08A 1j96B-3pcoA:
undetectable		 1j96B-3pcoA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTX_A_CVIA200_0
(HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR IN QACA
5'REGION)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
(Escherichia
coli) 		5 / 12 THR A 157
ILE A 133
ILE A 175
ALA A 142
THR A 163
 None
 1.19A 1jtxA-3pcoA:
undetectable		 1jtxA-3pcoA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_2
(DNA GYRASE SUBUNIT B)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		3 / 3 ASN A 217
PHE A 293
VAL B 479
 None
 0.58A 1kijA-3pcoA:
undetectable		 1kijA-3pcoA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT3_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
(Escherichia
coli) 		4 / 7 LEU A 267
MET A 304
LEU A 312
GLN A 200
 None
 1.11A 1kt3A-3pcoA:
undetectable		 1kt3A-3pcoA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA733_1
(ALPHA AMYLASE)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
(Escherichia
coli) 		4 / 6 SER A 171
THR A 170
ASN A 139
LEU A 165
 PHE  A 980 (-3.5A)
None
None
None
 1.34A 1mxdA-3pcoA:
undetectable		 1mxdA-3pcoA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PHG_A_MYTA422_1
(CYTOCHROME P450-CAM)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		5 / 11 GLY B 112
VAL B  64
ASP B  76
ILE B  77
VAL B  78
 None
 1.21A 1phgA-3pcoB:
undetectable		 1phgA-3pcoB:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA888_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		4 / 6 PRO B 449
MET B 455
GLU B 463
GLU B 464
 None
 1.48A 1qhyA-3pcoB:
undetectable		 1qhyA-3pcoB:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_F_BEZF5023_0
(CES1 PROTEIN)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		4 / 6 LEU B 287
GLY B 319
SER B 322
ILE B 304
 None
 0.87A 1yajF-3pcoB:
undetectable		 1yajF-3pcoB:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_K_BEZK4387_0
(CES1 PROTEIN)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		3 / 3 TRP B   7
LEU B   6
LYS B 152
 None
 1.40A 1yajK-3pcoB:
undetectable		 1yajK-3pcoB:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1507_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
(Escherichia
coli) 		3 / 3 GLN A 169
HIS A 155
ARG A 152
 PHE  A 980 (-3.5A)
None
None
 0.99A 1zlqA-3pcoA:
undetectable		 1zlqA-3pcoA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC2_0
(N8-ACTINOMYCIN D)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
(Escherichia
coli) 		3 / 3 THR A 110
PRO A 108
THR A 112
 None
 0.78A 209dC-3pcoA:
undetectable		 209dC-3pcoA:
5.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		5 / 12 LEU B 289
GLU B 334
GLY B 314
ASP B 300
ALA B 281
 None
 1.31A 2bm9B-3pcoB:
undetectable		 2bm9B-3pcoB:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		5 / 11 LEU B 669
LEU B 673
VAL B 557
ILE B 524
ALA B 554
 None
 1.16A 2q72A-3pcoB:
undetectable		 2q72A-3pcoB:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		5 / 12 LEU B 669
LEU B 673
VAL B 557
ILE B 524
ALA B 554
 None
 1.15A 2qb4A-3pcoB:
undetectable		 2qb4A-3pcoB:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VFU_A_MTLA1419_0
(XYLITOL OXIDASE)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
(Escherichia
coli) 		5 / 12 SER A 314
HIS A 107
PRO A 108
VAL A 109
THR A 303
 None
 1.31A 2vfuA-3pcoA:
1.2		 2vfuA-3pcoA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZT7_A_GLYA1300_0
(GLYCYL-TRNA
SYNTHETASE)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli;
Escherichia
coli) 		4 / 7 ARG A 281
GLU B 459
ARG B 409
GLU B 458
 None
 0.93A 2zt7A-3pcoA:
13.1		 2zt7A-3pcoA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		5 / 12 ASP B 201
ILE B 224
GLY B 386
LEU B 332
THR B 377
 None
 1.15A 3eeyF-3pcoB:
undetectable		 3eeyF-3pcoB:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli;
Escherichia
coli) 		5 / 12 ASN B 472
PHE A 243
VAL A 257
LEU A 227
ILE A 241
 None
 1.41A 3elzA-3pcoB:
undetectable		 3elzA-3pcoB:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FSU_A_C2FA995_0
(5,10-METHYLENETETRAH
YDROFOLATE REDUCTASE)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
(Escherichia
coli) 		5 / 12 THR A 112
ASN A 263
LEU A 312
THR A 203
LEU A 305
 None
None
None
AMP  A 992 (-3.7A)
None
 0.98A 3fsuA-3pcoA:
undetectable		 3fsuA-3pcoA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FSU_A_C2FA995_0
(5,10-METHYLENETETRAH
YDROFOLATE REDUCTASE)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
(Escherichia
coli) 		5 / 12 THR A 112
LEU A 267
LEU A 312
THR A 203
LEU A 305
 None
None
None
AMP  A 992 (-3.7A)
None
 1.28A 3fsuA-3pcoA:
undetectable		 3fsuA-3pcoA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_A_C2FA314_0
(UNCHARACTERIZED
PROTEIN)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		5 / 12 LEU B  21
VAL B  32
GLY B  34
LEU B   8
ILE B 172
 None
 1.10A 3ijdA-3pcoB:
undetectable		 3ijdA-3pcoB:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_0
(UNCHARACTERIZED
PROTEIN)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		5 / 12 LEU B  21
VAL B  32
GLY B  34
LEU B   8
ILE B 172
 None
 1.16A 3ijdB-3pcoB:
undetectable		 3ijdB-3pcoB:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_C_CELC682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
(Escherichia
coli) 		4 / 7 SER A 254
LEU A 231
ARG A 244
PHE A 243
 None
 1.09A 3ln1C-3pcoA:
undetectable		 3ln1C-3pcoA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_C_ACTC600_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		4 / 5 GLU B 361
ARG B 348
HIS B 353
ALA B 347
 None
 1.15A 3mbgB-3pcoB:
0.0
3mbgC-3pcoB:
0.0		 3mbgB-3pcoB:
9.94
3mbgC-3pcoB:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O1C_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		5 / 10 ILE B 511
ASP A 114
ILE A 113
LEU A 106
SER B 572
 None
 1.18A 3o1cA-3pcoB:
undetectable		 3o1cA-3pcoB:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O1X_A_ADNA1450_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		5 / 10 ILE B 511
ASP A 114
ILE A 113
LEU A 106
SER B 572
 None
 1.16A 3o1xA-3pcoB:
undetectable		 3o1xA-3pcoB:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_2
(PROTEASE)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		3 / 3 ARG B 244
VAL B  38
THR B 157
 None
 0.86A 3pwrA-3pcoB:
undetectable		 3pwrA-3pcoB:
8.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGZ_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		5 / 10 ILE B 511
ASP A 114
ILE A 113
LEU A 106
SER B 572
 None
 1.20A 3qgzA-3pcoB:
undetectable		 3qgzA-3pcoB:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_B_FLRB700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		5 / 12 VAL B 221
LEU B 380
VAL B 324
ALA B 266
LEU B 333
 None
 1.06A 3rr3B-3pcoB:
undetectable		 3rr3B-3pcoB:
22.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TEG_A_DAHA416_1
(PHENYLALANYL-TRNA
SYNTHETASE,
MITOCHONDRIAL)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
(Escherichia
coli) 		11 / 12 SER A 171
ARG A 195
GLN A 208
GLU A 210
PHE A 248
PHE A 250
THR A 251
GLY A 271
GLY A 273
ALA A 294
GLY A 296
 PHE  A 980 (-3.5A)
AMP  A 992 (-4.0A)
PHE  A 980 ( 3.6A)
PHE  A 980 (-3.0A)
PHE  A 980 (-3.6A)
PHE  A 980 (-4.5A)
PHE  A 980 ( 4.1A)
PHE  A 980 (-4.0A)
None
PHE  A 980 ( 4.0A)
PHE  A 980 (-3.6A)
 0.61A 3tegA-3pcoA:
25.1		 3tegA-3pcoA:
30.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TEG_A_DAHA416_1
(PHENYLALANYL-TRNA
SYNTHETASE,
MITOCHONDRIAL)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
(Escherichia
coli) 		11 / 12 SER A 171
GLN A 174
ARG A 195
GLN A 208
PHE A 248
PHE A 250
THR A 251
GLY A 271
GLY A 273
ALA A 294
GLY A 296
 PHE  A 980 (-3.5A)
PHE  A 980 ( 4.5A)
AMP  A 992 (-4.0A)
PHE  A 980 ( 3.6A)
PHE  A 980 (-3.6A)
PHE  A 980 (-4.5A)
PHE  A 980 ( 4.1A)
PHE  A 980 (-4.0A)
None
PHE  A 980 ( 4.0A)
PHE  A 980 (-3.6A)
 0.65A 3tegA-3pcoA:
25.1		 3tegA-3pcoA:
30.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TEH_A_DAHA351_1
(PHENYLALANYL-TRNA
SYNTHETASE ALPHA
CHAIN)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
(Escherichia
coli) 		6 / 9 SER A 171
ARG A 195
GLN A 208
GLU A 210
ALA A 294
GLY A 296
 PHE  A 980 (-3.5A)
AMP  A 992 (-4.0A)
PHE  A 980 ( 3.6A)
PHE  A 980 (-3.0A)
PHE  A 980 ( 4.0A)
PHE  A 980 (-3.6A)
 0.58A 3tehA-3pcoA:
28.6		 3tehA-3pcoA:
45.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TEH_B_DAHB786_1
(PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		4 / 7 HIS B 265
LEU B 290
GLY B 314
GLU B 334
 None
 1.00A 3tehB-3pcoB:
undetectable		 3tehB-3pcoB:
38.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TEH_B_DAHB786_1
(PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		6 / 7 PRO B 263
HIS B 265
LEU B 290
GLY B 315
GLU B 334
ALA B 356
 None
 0.84A 3tehB-3pcoB:
undetectable		 3tehB-3pcoB:
38.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_C_ACTC502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		3 / 3 PRO B 475
ASP B 476
GLU B 477
 None
 0.72A 3v4tC-3pcoB:
undetectable		 3v4tC-3pcoB:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VNS_A_DVAA602_0
(NRPS ADENYLATION
PROTEIN CYTC1)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
(Escherichia
coli) 		4 / 7 PHE A 220
GLY A 273
THR A 226
PHE A 243
 None
 1.03A 3vnsA-3pcoA:
undetectable		 3vnsA-3pcoA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		4 / 7 VAL B 250
ILE B 246
ASN B 254
GLU B 334
 None
 1.09A 4a97E-3pcoB:
undetectable		 4a97E-3pcoB:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		4 / 8 VAL B 250
ILE B 246
ASN B 254
GLU B 334
 None
 1.07A 4a97C-3pcoB:
undetectable		 4a97C-3pcoB:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_E_ZPCE1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		4 / 8 VAL B 250
ILE B 246
ASN B 254
GLU B 334
 None
 1.06A 4a97D-3pcoB:
undetectable		 4a97D-3pcoB:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		4 / 8 VAL B 250
ILE B 246
ASN B 254
GLU B 334
 None
 1.09A 4a97G-3pcoB:
undetectable		 4a97G-3pcoB:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_I_ZPCI1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		4 / 7 VAL B 250
ILE B 246
ASN B 254
GLU B 334
 None
 1.01A 4a97H-3pcoB:
undetectable		 4a97H-3pcoB:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_J_ZPCJ1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		4 / 8 VAL B 250
ILE B 246
ASN B 254
GLU B 334
 None
 1.01A 4a97I-3pcoB:
undetectable		 4a97I-3pcoB:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DFU_A_KANA401_1
(APH(2')-ID)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		5 / 12 ASP B 168
ASP B 178
GLU B 463
GLU B 464
GLU A 252
 None
 1.30A 4dfuA-3pcoB:
undetectable		 4dfuA-3pcoB:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		4 / 8 LEU B 574
VAL A 173
THR A 129
GLY A 191
 None
 0.86A 4eq4B-3pcoB:
undetectable		 4eq4B-3pcoB:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		4 / 7 GLU B 361
TYR B 360
GLY B 261
ARG B 359
 None
 1.04A 4fgzA-3pcoB:
undetectable		 4fgzA-3pcoB:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_C_ECNC403_1
(FLAVOHEMOGLOBIN)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		5 / 9 ILE B 524
LEU B 669
VAL B 665
VAL B 557
LEU B 553
 None
 1.22A 4g1bC-3pcoB:
undetectable		 4g1bC-3pcoB:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KSZ_A_CYSA620_0
(LACTOPEROXIDASE)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
(Escherichia
coli) 		3 / 3 ARG A 301
GLU A 300
PHE A 315
 AMP  A 992 (-3.7A)
None
None
 0.82A 4kszA-3pcoA:
undetectable		 4kszA-3pcoA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA603_1
(SERUM ALBUMIN)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
(Escherichia
coli) 		5 / 11 ARG A 301
LEU A 305
LEU A 231
LEU A 267
LEU A 239
 AMP  A 992 (-3.7A)
None
None
None
None
 1.34A 4or0A-3pcoA:
undetectable		 4or0A-3pcoA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB204_1
(CALMODULIN)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		4 / 8 LEU B 584
GLY B 585
MET B 544
ALA B 530
 None
 0.83A 4rjdA-3pcoB:
undetectable
4rjdB-3pcoB:
undetectable		 4rjdA-3pcoB:
6.97
4rjdB-3pcoB:
6.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8Y_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		5 / 12 GLU B 633
ILE B 652
ALA B 650
PHE B 614
VAL B 662
 None
 0.95A 4u8yB-3pcoB:
undetectable		 4u8yB-3pcoB:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		5 / 12 VAL B 331
VAL B 221
LEU B 380
THR B 377
ALA B 376
 None
 0.90A 4yhaA-3pcoB:
undetectable		 4yhaA-3pcoB:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE0_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
(Escherichia
coli) 		5 / 9 THR A 251
PHE A 250
PHE A 248
LEU A 270
LEU A 227
 PHE  A 980 ( 4.1A)
PHE  A 980 (-4.5A)
PHE  A 980 (-3.6A)
None
None
 1.43A 4ze0A-3pcoA:
undetectable		 4ze0A-3pcoA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli;
Escherichia
coli) 		4 / 6 LYS B 499
GLU B 509
GLY A 105
GLY A 104
 None
 1.04A 5a06D-3pcoB:
undetectable		 5a06D-3pcoB:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G08_A_Z80A1187_1
(FREQUENIN 2)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
(Escherichia
coli) 		4 / 6 ILE A 175
PHE A 250
THR A 157
TRP A 159
 None
PHE  A 980 (-4.5A)
None
None
 1.36A 5g08A-3pcoA:
undetectable		 5g08A-3pcoA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_B_ACTB1321_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		3 / 3 THR B 354
ASP B 355
ALA B 356
 None
 0.11A 5g5gB-3pcoB:
undetectable		 5g5gB-3pcoB:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		5 / 9 ALA B  93
THR B  94
ALA B  97
GLY B  48
ALA B  91
 None
 1.09A 5l5zK-3pcoB:
undetectable
5l5zL-3pcoB:
undetectable		 5l5zK-3pcoB:
12.20
5l5zL-3pcoB:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		5 / 9 ALA B  93
THR B  94
ALA B  97
GLY B  48
ALA B  91
 None
 1.09A 5l5zY-3pcoB:
undetectable
5l5zZ-3pcoB:
undetectable		 5l5zY-3pcoB:
12.20
5l5zZ-3pcoB:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUE_A_VIVA302_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		5 / 12 ILE B 134
PHE B 122
ILE B 147
LEU B 153
ILE B 127
 None
 0.96A 5mueA-3pcoB:
undetectable		 5mueA-3pcoB:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_C_9UQC202_0
(CEREBLON ISOFORM 4)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
(Escherichia
coli) 		4 / 8 ASN A 318
GLU A 300
PHE A 315
TYR A 198
 None
 1.46A 5oh1C-3pcoA:
2.2		 5oh1C-3pcoA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		4 / 8 VAL B 331
LEU B 380
THR B 377
ALA B 376
 None
 0.57A 5tt3H-3pcoB:
undetectable		 5tt3H-3pcoB:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAH_C_RFPC3001_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		5 / 12 ARG B 467
GLN B  24
VAL B 162
LEU B  21
ILE B 158
 None
 1.34A 5uahC-3pcoB:
undetectable		 5uahC-3pcoB:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Z_A_BHAA201_0
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
(Escherichia
coli) 		4 / 6 LEU A 270
VAL A 269
LEU A 302
VAL A 259
 None
 0.87A 5x7zA-3pcoA:
undetectable		 5x7zA-3pcoA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli;
Escherichia
coli) 		4 / 8 GLU B 509
HIS A 207
PHE B 515
MET B 541
 None
 0.97A 5y2tB-3pcoB:
undetectable		 5y2tB-3pcoB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0C_D_TA1D502_1
(TUBULIN BETA CHAIN)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		5 / 12 VAL B  45
LEU B 232
ALA B  91
ARG B 240
GLY B 126
 None
 0.91A 6b0cD-3pcoB:
undetectable		 6b0cD-3pcoB:
8.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BNI_A_ADNA602_1
(LYSINE--TRNA LIGASE)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
(Escherichia
coli) 		6 / 10 ARG A 195
HIS A 202
PHE A 206
GLU A 268
GLY A 298
ARG A 301
 AMP  A 992 (-4.0A)
AMP  A 992 (-3.6A)
AMP  A 992 (-3.5A)
AMP  A 992 (-3.8A)
AMP  A 992 ( 4.4A)
AMP  A 992 (-3.7A)
 0.80A 6bniA-3pcoA:
15.0		 6bniA-3pcoA:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BNI_B_ADNB602_1
(LYSINE--TRNA LIGASE)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
(Escherichia
coli) 		6 / 10 ARG A 195
HIS A 202
PHE A 206
GLU A 268
GLY A 298
ARG A 301
 AMP  A 992 (-4.0A)
AMP  A 992 (-3.6A)
AMP  A 992 (-3.5A)
AMP  A 992 (-3.8A)
AMP  A 992 ( 4.4A)
AMP  A 992 (-3.7A)
 0.78A 6bniB-3pcoA:
15.8		 6bniB-3pcoA:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli;
Escherichia
coli) 		4 / 7 ALA B 554
THR B 555
TYR B 558
PRO A 204
 None
 0.87A 6cduA-3pcoB:
undetectable
6cduE-3pcoB:
undetectable		 6cduA-3pcoB:
18.99
6cduE-3pcoB:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_E_EY4E500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli;
Escherichia
coli) 		4 / 8 PRO A 204
ALA B 554
THR B 555
TYR B 558
 None
 0.86A 6cduD-3pcoA:
undetectable
6cduE-3pcoA:
undetectable		 6cduD-3pcoA:
21.61
6cduE-3pcoA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_H_EY4H500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli;
Escherichia
coli) 		4 / 7 PRO A 204
ALA B 554
THR B 555
TYR B 558
 None
 0.90A 6cduH-3pcoA:
undetectable
6cduI-3pcoA:
undetectable		 6cduH-3pcoA:
21.61
6cduI-3pcoA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_2
(-)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT
PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		5 / 12 LEU A 227
LEU A 223
GLY A 296
GLY A 271
ASN B 472
 None
None
PHE  A 980 (-3.6A)
PHE  A 980 (-4.0A)
None
 0.89A 6ce2B-3pcoA:
undetectable		 6ce2B-3pcoA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_B_HISB402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		5 / 9 VAL B 557
VAL B 665
GLY B 594
LEU B 552
THR B 679
 None
 1.35A 6czmA-3pcoB:
undetectable
6czmB-3pcoB:
2.6		 6czmA-3pcoB:
17.63
6czmB-3pcoB:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_C_HISC402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		5 / 9 VAL B 557
VAL B 665
GLY B 594
LEU B 552
THR B 679
 None
 1.34A 6czmB-3pcoB:
2.6
6czmC-3pcoB:
3.5		 6czmB-3pcoB:
17.63
6czmC-3pcoB:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E5Z_A_CCSA106_0
(PROTEIN/NUCLEIC ACID
DEGLYCASE DJ-1)		 3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN
(Escherichia
coli) 		5 / 10 GLY B  70
GLY B  71
ILE B 143
THR B 145
GLY B  48
 None
 1.04A 6e5zA-3pcoB:
undetectable		 6e5zA-3pcoB:
14.20