SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pct'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA8_0
(GRAMICIDIN A)		 3pct CLASS C ACID
PHOSPHATASE
(Pasteurella
multocida) 		3 / 4 VAL A  94
TRP A  77
TRP A  90
 None
 1.08A 1gmkA-3pctA:
undetectable
1gmkB-3pctA:
undetectable		 1gmkA-3pctA:
5.18
1gmkB-3pctA:
5.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC2_0
(N8-ACTINOMYCIN D)		 3pct CLASS C ACID
PHOSPHATASE
(Pasteurella
multocida) 		3 / 3 THR A  89
PRO A  87
THR A  91
 None
 0.80A 209dC-3pctA:
undetectable		 209dC-3pctA:
5.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3pct CLASS C ACID
PHOSPHATASE
(Pasteurella
multocida) 		3 / 3 ASP A 222
ASP A 180
ASN A 159
 None
 0.72A 2bm9D-3pctA:
3.1		 2bm9D-3pctA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3pct CLASS C ACID
PHOSPHATASE
(Pasteurella
multocida) 		3 / 3 ASP A 222
TYR A 190
LYS A 160
 None
 0.99A 2othA-3pctA:
undetectable		 2othA-3pctA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_B_GJZB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3pct CLASS C ACID
PHOSPHATASE
(Pasteurella
multocida) 		4 / 6 PHE A 143
ILE A  69
ALA A 101
ALA A  36
 None
 0.97A 3mdrB-3pctA:
undetectable		 3mdrB-3pctA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3pct CLASS C ACID
PHOSPHATASE
(Pasteurella
multocida) 		5 / 11 VAL A 178
LEU A 215
ILE A 102
GLY A 104
ALA A 105
 None
 1.06A 3n8yA-3pctA:
undetectable		 3n8yA-3pctA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3pct CLASS C ACID
PHOSPHATASE
(Pasteurella
multocida) 		4 / 8 ASP A  63
ASP A 187
ASP A 156
ASN A 124
 None
 1.00A 4gkhC-3pctA:
undetectable
4gkhK-3pctA:
undetectable		 4gkhC-3pctA:
21.93
4gkhK-3pctA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3pct CLASS C ACID
PHOSPHATASE
(Pasteurella
multocida) 		4 / 8 ASP A  63
ASP A 187
ASP A 156
ASN A 124
 None
 1.00A 4gkiE-3pctA:
undetectable
4gkiG-3pctA:
undetectable		 4gkiE-3pctA:
21.93
4gkiG-3pctA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_3
(PROTEASE)		 3pct CLASS C ACID
PHOSPHATASE
(Pasteurella
multocida) 		3 / 3 ASP A 184
ASP A 180
ASN A  71
 None
 0.71A 4q5mA-3pctA:
undetectable		 4q5mA-3pctA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		 3pct CLASS C ACID
PHOSPHATASE
(Pasteurella
multocida) 		4 / 8 ASP A 180
TYR A  32
SER A  99
ASN A  71
 None
 1.14A 5l1fA-3pctA:
undetectable
5l1fB-3pctA:
undetectable		 5l1fA-3pctA:
16.56
5l1fB-3pctA:
16.56