SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pd7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KGL_A_RTLA175_0
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)		 3pd7 DNA TOPOISOMERASE
2-BINDING PROTEIN 1
(Homo
sapiens) 		5 / 12 ALA A 932
PRO A 904
GLY A 925
ILE A 926
LEU A 984
 None
 1.28A 1kglA-3pd7A:
undetectable		 1kglA-3pd7A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_B_DXCB92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3pd7 DNA TOPOISOMERASE
2-BINDING PROTEIN 1
(Homo
sapiens) 		4 / 5 VAL A 909
VAL A 942
ARG A 935
LYS A 914
 None
 1.50A 3rv5A-3pd7A:
undetectable
3rv5B-3pd7A:
undetectable		 3rv5A-3pd7A:
19.09
3rv5B-3pd7A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_A_032A401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 3pd7 DNA TOPOISOMERASE
2-BINDING PROTEIN 1
(Homo
sapiens) 		4 / 6 LYS A 915
SER A 960
VAL A 961
ASP A 953
 None
 1.26A 5hesA-3pd7A:
undetectable		 5hesA-3pd7A:
15.51