SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pdk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4003_1
(SERUM ALBUMIN)		 3pdk PHOSPHOGLUCOSAMINE
MUTASE
(Bacillus
anthracis) 		5 / 9 ILE A 264
LEU A 237
VAL A 256
ALA A 363
LEU A 359
 None
 1.15A 1e7bA-3pdkA:
undetectable		 1e7bA-3pdkA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3003_1
(SERUM ALBUMIN)		 3pdk PHOSPHOGLUCOSAMINE
MUTASE
(Bacillus
anthracis) 		4 / 6 HIS A 175
ILE A 176
ALA A 248
VAL A 349
 None
 0.97A 1hk1A-3pdkA:
undetectable		 1hk1A-3pdkA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_A_VIBA502_1
(THIAMIN
PYROPHOSPHOKINASE)		 3pdk PHOSPHOGLUCOSAMINE
MUTASE
(Bacillus
anthracis) 		4 / 8 SER A 186
SER A 206
ASP A 179
THR A 202
 None
 1.05A 1ig3A-3pdkA:
2.2
1ig3B-3pdkA:
2.4		 1ig3A-3pdkA:
20.99
1ig3B-3pdkA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ1_A_HLTA2001_1
(FERRITIN LIGHT CHAIN)		 3pdk PHOSPHOGLUCOSAMINE
MUTASE
(Bacillus
anthracis) 		4 / 4 LEU A 188
SER A 187
TYR A 191
LEU A 160
 None
 1.32A 1xz1A-3pdkA:
1.7		 1xz1A-3pdkA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3pdk PHOSPHOGLUCOSAMINE
MUTASE
(Bacillus
anthracis) 		4 / 8 LEU A  34
LEU A  60
VAL A  10
GLY A   9
 None
 0.84A 2po5B-3pdkA:
2.0		 2po5B-3pdkA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRH_A_NIOA200_1
(PROTEIN HP0721)		 3pdk PHOSPHOGLUCOSAMINE
MUTASE
(Bacillus
anthracis) 		4 / 7 GLY A 156
THR A  86
MET A  96
LEU A  74
 None
 0.73A 2xrhA-3pdkA:
undetectable		 2xrhA-3pdkA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YHD_A_TESA1920_1
(ANDROGEN RECEPTOR)		 3pdk PHOSPHOGLUCOSAMINE
MUTASE
(Bacillus
anthracis) 		5 / 12 LEU A 343
LEU A 322
GLY A 323
MET A 312
MET A 315
 None
None
None
PO4  A 450 (-4.4A)
None
 1.49A 2yhdA-3pdkA:
undetectable		 2yhdA-3pdkA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_B_REMB350_1
(RENIN)		 3pdk PHOSPHOGLUCOSAMINE
MUTASE
(Bacillus
anthracis) 		5 / 12 ASP A 242
GLY A 243
SER A 218
THR A 219
ASP A 244
 None
 1.22A 3d91B-3pdkA:
undetectable		 3d91B-3pdkA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID801_0
(GLUTAMATE RECEPTOR 2)		 3pdk PHOSPHOGLUCOSAMINE
MUTASE
(Bacillus
anthracis) 		4 / 8 SER A 286
ILE A 330
SER A 282
GLY A 324
 None
 0.93A 3lslA-3pdkA:
2.6
3lslD-3pdkA:
3.0		 3lslA-3pdkA:
20.34
3lslD-3pdkA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3pdk PHOSPHOGLUCOSAMINE
MUTASE
(Bacillus
anthracis) 		5 / 10 ILE A 264
PHE A 239
ALA A 177
LEU A 237
ALA A 238
 None
 1.33A 3lw5B-3pdkA:
undetectable		 3lw5B-3pdkA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_2
(CANDIDAPEPSIN-2)		 3pdk PHOSPHOGLUCOSAMINE
MUTASE
(Bacillus
anthracis) 		4 / 6 THR A 185
SER A 344
ILE A 261
ASP A 179
 None
 1.02A 3q70A-3pdkA:
undetectable		 3q70A-3pdkA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_B_ESLB700_1
(ESTROGEN RECEPTOR)		 3pdk PHOSPHOGLUCOSAMINE
MUTASE
(Bacillus
anthracis) 		5 / 12 LEU A 348
ALA A 345
LEU A 246
ILE A 331
GLY A 339
 None
None
None
None
PO4  A 450 (-4.3A)
 1.04A 3q95B-3pdkA:
undetectable		 3q95B-3pdkA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_A_EVPA1_1
(DNA TOPOISOMERASE
2-BETA)		 3pdk PHOSPHOGLUCOSAMINE
MUTASE
(Bacillus
anthracis) 		4 / 5 GLY A 243
ASP A 242
ARG A 245
MET A 315
 None
 1.11A 3qx3A-3pdkA:
undetectable		 3qx3A-3pdkA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_D_EVPD1_1
(DNA TOPOISOMERASE
2-BETA)		 3pdk PHOSPHOGLUCOSAMINE
MUTASE
(Bacillus
anthracis) 		4 / 5 GLY A 243
ASP A 242
ARG A 245
MET A 315
 None
 1.09A 3qx3B-3pdkA:
undetectable		 3qx3B-3pdkA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NTX_A_AMRA509_1
(ACID-SENSING ION
CHANNEL 1
BASIC PHOSPHOLIPASE
A2 HOMOLOG TX-BETA)		 3pdk PHOSPHOGLUCOSAMINE
MUTASE
(Bacillus
anthracis) 		4 / 6 ASP A 244
ASP A 242
ASN A 102
ARG A  11
 None
 1.09A 4ntxA-3pdkA:
2.4
4ntxC-3pdkA:
undetectable		 4ntxA-3pdkA:
22.49
4ntxC-3pdkA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3pdk PHOSPHOGLUCOSAMINE
MUTASE
(Bacillus
anthracis) 		5 / 11 THR A  35
THR A  38
GLY A 113
ALA A  91
THR A  86
 None
 1.46A 4qvlV-3pdkA:
undetectable
4qvlb-3pdkA:
undetectable		 4qvlV-3pdkA:
23.52
4qvlb-3pdkA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3pdk PHOSPHOGLUCOSAMINE
MUTASE
(Bacillus
anthracis) 		5 / 11 THR A  35
THR A  38
GLY A 113
ALA A  91
THR A  86
 None
 1.46A 4qvlH-3pdkA:
undetectable
4qvlN-3pdkA:
undetectable		 4qvlH-3pdkA:
23.52
4qvlN-3pdkA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3pdk PHOSPHOGLUCOSAMINE
MUTASE
(Bacillus
anthracis) 		5 / 11 THR A  35
THR A  38
GLY A 113
ALA A  91
THR A  86
 None
 1.46A 4qvmH-3pdkA:
undetectable
4qvmN-3pdkA:
undetectable		 4qvmH-3pdkA:
23.52
4qvmN-3pdkA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3pdk PHOSPHOGLUCOSAMINE
MUTASE
(Bacillus
anthracis) 		5 / 11 THR A  35
THR A  38
GLY A 113
ALA A  91
THR A  86
 None
 1.47A 4qvwV-3pdkA:
undetectable
4qvwb-3pdkA:
undetectable		 4qvwV-3pdkA:
23.52
4qvwb-3pdkA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3pdk PHOSPHOGLUCOSAMINE
MUTASE
(Bacillus
anthracis) 		5 / 11 THR A  35
THR A  38
GLY A 113
ALA A  91
THR A  86
 None
 1.47A 4qw0V-3pdkA:
undetectable
4qw0b-3pdkA:
undetectable		 4qw0V-3pdkA:
23.52
4qw0b-3pdkA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3pdk PHOSPHOGLUCOSAMINE
MUTASE
(Bacillus
anthracis) 		5 / 11 THR A  35
THR A  38
GLY A 113
ALA A  91
THR A  86
 None
 1.46A 4qw0H-3pdkA:
undetectable
4qw0N-3pdkA:
undetectable		 4qw0H-3pdkA:
23.52
4qw0N-3pdkA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDR_A_ADNA402_1
(FAD:PROTEIN FMN
TRANSFERASE)		 3pdk PHOSPHOGLUCOSAMINE
MUTASE
(Bacillus
anthracis) 		6 / 12 PHE A 112
GLY A  81
ILE A  44
ILE A  45
THR A  86
VAL A  43
 None
 1.28A 4xdrA-3pdkA:
2.5		 4xdrA-3pdkA:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3pdk PHOSPHOGLUCOSAMINE
MUTASE
(Bacillus
anthracis) 		5 / 11 THR A  35
THR A  38
GLY A 113
ALA A  91
THR A  86
 None
 1.47A 5d0xH-3pdkA:
undetectable
5d0xN-3pdkA:
undetectable		 5d0xH-3pdkA:
23.52
5d0xN-3pdkA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_B_PFLB510_1
(PROTON-GATED ION
CHANNEL)		 3pdk PHOSPHOGLUCOSAMINE
MUTASE
(Bacillus
anthracis) 		4 / 6 ILE A 235
ALA A 345
LEU A 348
ILE A 261
 None
 0.78A 5mvmB-3pdkA:
undetectable
5mvmC-3pdkA:
undetectable		 5mvmB-3pdkA:
11.59
5mvmC-3pdkA:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 3pdk PHOSPHOGLUCOSAMINE
MUTASE
(Bacillus
anthracis) 		5 / 10 ILE A 235
ALA A 345
LEU A 348
ILE A 261
ILE A 255
 None
 0.96A 5mvmD-3pdkA:
undetectable
5mvmE-3pdkA:
undetectable		 5mvmD-3pdkA:
11.59
5mvmE-3pdkA:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRF_D_EVPD101_1
()		 3pdk PHOSPHOGLUCOSAMINE
MUTASE
(Bacillus
anthracis) 		4 / 5 GLY A 243
ASP A 242
ARG A 245
MET A 315
 None
 1.13A 5zrfB-3pdkA:
undetectable		 5zrfB-3pdkA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRF_F_EVPF1301_1
()		 3pdk PHOSPHOGLUCOSAMINE
MUTASE
(Bacillus
anthracis) 		4 / 4 GLY A 243
ASP A 242
ARG A 245
MET A 315
 None
 1.14A 5zrfA-3pdkA:
undetectable		 5zrfA-3pdkA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DEB_B_MTXB303_1
(BIFUNCTIONAL PROTEIN
FOLD)		 3pdk PHOSPHOGLUCOSAMINE
MUTASE
(Bacillus
anthracis) 		4 / 5 TYR A 162
GLN A 165
GLY A 341
ILE A 336
 None
 1.49A 6debB-3pdkA:
3.3		 6debB-3pdkA:
10.41