SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pe0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3pe0 PLECTIN
(Homo
sapiens) 		4 / 6 ARG A 814
GLY A 810
ALA A 812
HIS A 807
 None
 0.90A 1wmqA-3pe0A:
undetectable		 1wmqA-3pe0A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3pe0 PLECTIN
(Homo
sapiens) 		4 / 6 ARG A 814
GLY A 810
ALA A 812
HIS A 807
 None
 0.91A 1wmqB-3pe0A:
undetectable		 1wmqB-3pe0A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3pe0 PLECTIN
(Homo
sapiens) 		4 / 6 ARG A 814
GLY A 810
ALA A 812
HIS A 807
 None
 0.92A 1wpuA-3pe0A:
undetectable		 1wpuA-3pe0A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3pe0 PLECTIN
(Homo
sapiens) 		4 / 6 ARG A 814
GLY A 810
ALA A 812
HIS A 807
 None
 0.91A 1wpuB-3pe0A:
undetectable		 1wpuB-3pe0A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3pe0 PLECTIN
(Homo
sapiens) 		4 / 6 ARG A 814
GLY A 810
ALA A 812
HIS A 807
 None
 0.92A 1wrqA-3pe0A:
undetectable		 1wrqA-3pe0A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3pe0 PLECTIN
(Homo
sapiens) 		4 / 6 ARG A 814
GLY A 810
ALA A 812
HIS A 807
 None
 0.92A 1wrqB-3pe0A:
undetectable		 1wrqB-3pe0A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F33_A_PFLA2001_1
(FERRITIN LIGHT CHAIN)		 3pe0 PLECTIN
(Homo
sapiens) 		4 / 6 SER A 684
TYR A 685
LEU A 688
LEU A 745
 None
 0.65A 3f33A-3pe0A:
4.3		 3f33A-3pe0A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_B_ACTB804_0
(UNCHARACTERIZED
PROTEIN)		 3pe0 PLECTIN
(Homo
sapiens) 		4 / 4 HIS A 807
VAL A 896
LEU A 811
ALA A 761
 None
 1.17A 6d8pB-3pe0A:
undetectable		 6d8pB-3pe0A:
16.60